8I8L

Crystal structure of the ternary complex of Phosphopantetheine adenylyltransferase (PPAT) from Enterobacter sp. with Coenzyme-A and Phosphonoacetic acid at 2.23 A resolution.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0009058	biological_process	biosynthetic process
A	0015937	biological_process	coenzyme A biosynthetic process
A	0016779	molecular_function	nucleotidyltransferase activity
B	0003824	molecular_function	catalytic activity
B	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0009058	biological_process	biosynthetic process
B	0015937	biological_process	coenzyme A biosynthetic process
B	0016779	molecular_function	nucleotidyltransferase activity
C	0003824	molecular_function	catalytic activity
C	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0009058	biological_process	biosynthetic process
C	0015937	biological_process	coenzyme A biosynthetic process
C	0016779	molecular_function	nucleotidyltransferase activity
D	0003824	molecular_function	catalytic activity
D	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0009058	biological_process	biosynthetic process
D	0015937	biological_process	coenzyme A biosynthetic process
D	0016779	molecular_function	nucleotidyltransferase activity
E	0003824	molecular_function	catalytic activity
E	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0009058	biological_process	biosynthetic process
E	0015937	biological_process	coenzyme A biosynthetic process
E	0016779	molecular_function	nucleotidyltransferase activity
F	0003824	molecular_function	catalytic activity
F	0004595	molecular_function	pantetheine-phosphate adenylyltransferase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0009058	biological_process	biosynthetic process
F	0015937	biological_process	coenzyme A biosynthetic process
F	0016779	molecular_function	nucleotidyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00151

Chain	Residue	Details
A	THR10
A	HIS18
A	LYS42
A	MET74
A	ARG88
A	GLY89
A	GLU99
A	TRP124
B	THR10
B	HIS18
B	LYS42
B	MET74
B	ARG88
B	GLY89
B	GLU99
B	TRP124
C	THR10
C	HIS18
C	LYS42
C	MET74
C	ARG88
C	GLY89
C	GLU99
C	TRP124
D	THR10
D	HIS18
D	LYS42
D	MET74
D	ARG88
D	GLY89
D	GLU99
D	TRP124
E	THR10
E	HIS18
E	LYS42
E	MET74
E	ARG88
E	GLY89
E	GLU99
E	TRP124
F	THR10
F	HIS18
F	LYS42
F	MET74
F	ARG88
F	GLY89
F	GLU99
F	TRP124

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151

Chain	Residue	Details
A	HIS18
B	HIS18
C	HIS18
D	HIS18
E	HIS18
F	HIS18

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