8I5N
Rat Kir4.1 in complex with PIP2 and Lys05
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 96 |
| Details | TRANSMEM: Helical; Name=M1 => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG65-VAL89 | |
| B | ARG65-VAL89 | |
| C | ARG65-VAL89 | |
| D | ARG65-VAL89 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 128 |
| Details | TOPO_DOM: Extracellular => ECO:0000250 |
| Chain | Residue | Details |
| A | ALA90-THR114 | |
| A | ARG134-LEU142 | |
| B | ALA90-THR114 | |
| B | ARG134-LEU142 | |
| C | ALA90-THR114 | |
| C | ARG134-LEU142 | |
| D | ALA90-THR114 | |
| D | ARG134-LEU142 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 44 |
| Details | INTRAMEM: Helical; Pore-forming; Name=H5 => ECO:0000250 |
| Chain | Residue | Details |
| A | LEU115-GLN126 | |
| B | LEU115-GLN126 | |
| C | LEU115-GLN126 | |
| D | LEU115-GLN126 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 24 |
| Details | INTRAMEM: Pore-forming => ECO:0000250 |
| Chain | Residue | Details |
| A | THR127-PHE133 | |
| B | THR127-PHE133 | |
| C | THR127-PHE133 | |
| D | THR127-PHE133 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 84 |
| Details | TRANSMEM: Helical; Name=M2 => ECO:0000250 |
| Chain | Residue | Details |
| A | ALA143-THR164 | |
| B | ALA143-THR164 | |
| C | ALA143-THR164 | |
| D | ALA143-THR164 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY210 | |
| B | GLY210 | |
| C | GLY210 | |
| D | GLY210 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | SITE: Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesium => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU158 | |
| B | GLU158 | |
| C | GLU158 | |
| D | GLU158 |
