8HD3
Farnesoid X Receptor Agonists_FXR fused with a HD3 peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0032052 | molecular_function | bile acid binding |
| A | 0038183 | biological_process | bile acid signaling pathway |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0032052 | molecular_function | bile acid binding |
| B | 0038183 | biological_process | bile acid signaling pathway |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0007744|PDB:6HL1 |
| Chain | Residue | Details |
| A | ARG345 | |
| A | TYR375 | |
| A | TYR383 | |
| A | HIS461 | |
| B | ARG345 | |
| B | TYR375 | |
| B | TYR383 | |
| B | HIS461 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by PKC/PRKCZ => ECO:0000305|PubMed:18668687 |
| Chain | Residue | Details |
| A | THR456 | |
| B | THR456 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000305|PubMed:23546875 |
| Chain | Residue | Details |
| A | LYS289 | |
| B | LYS289 |
