8FU7
Structure of Covid Spike variant deltaN135 in fully closed form
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0016020 | cellular_component | membrane |
A | 0019031 | cellular_component | viral envelope |
A | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
A | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
A | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
A | 0055036 | cellular_component | virion membrane |
A | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
B | 0016020 | cellular_component | membrane |
B | 0019031 | cellular_component | viral envelope |
B | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
B | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
B | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
B | 0055036 | cellular_component | virion membrane |
B | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
C | 0016020 | cellular_component | membrane |
C | 0019031 | cellular_component | viral envelope |
C | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
C | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
C | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
C | 0055036 | cellular_component | virion membrane |
C | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | SITE: Cleavage; by host furin => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32142651, ECO:0000269|PubMed:32362314, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
Chain | Residue | Details |
A | ALA685 | |
B | ALA685 | |
C | ALA685 |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
Chain | Residue | Details |
A | ALA815 | |
B | ALA815 | |
C | ALA815 |
site_id | SWS_FT_FI3 |
Number of Residues | 9 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN17 | |
A | ALA1158 | |
A | VAL1173 | |
B | ASN17 | |
B | ALA1158 | |
B | VAL1173 | |
C | ASN17 | |
C | ALA1158 | |
C | VAL1173 |
site_id | SWS_FT_FI4 |
Number of Residues | 15 |
Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN61 | |
B | PRO1074 | |
C | ASN61 | |
C | ASN122 | |
C | LYS717 | |
C | PHE801 | |
C | PRO1074 | |
A | ASN122 | |
A | LYS717 | |
A | PHE801 | |
A | PRO1074 | |
B | ASN61 | |
B | ASN122 | |
B | LYS717 | |
B | PHE801 |
site_id | SWS_FT_FI5 |
Number of Residues | 9 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ASN74 | |
A | ARG149 | |
B | ASN74 | |
B | ARG149 | |
C | ASN74 | |
C | ARG149 |
site_id | SWS_FT_FI6 |
Number of Residues | 21 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | PRO165 | |
B | PHE331 | |
B | SER343 | |
B | THR616 | |
B | SER657 | |
B | ILE1098 | |
C | PRO165 | |
C | GLU282 | |
C | PHE331 | |
C | SER343 | |
C | THR616 | |
A | GLU282 | |
C | SER657 | |
C | ILE1098 | |
A | PHE331 | |
A | SER343 | |
A | THR616 | |
A | SER657 | |
A | ILE1098 | |
B | PRO165 | |
B | GLU282 |
site_id | SWS_FT_FI7 |
Number of Residues | 6 |
Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | ALA234 | |
A | GLU709 | |
B | ALA234 | |
B | GLU709 | |
C | ALA234 | |
C | GLU709 |
site_id | SWS_FT_FI8 |
Number of Residues | 3 |
Details | CARBOHYD: O-linked (GalNAc) threonine; by host => ECO:0000269|PubMed:32363391 |
Chain | Residue | Details |
A | GLY323 | |
B | GLY323 | |
C | GLY323 |
site_id | SWS_FT_FI9 |
Number of Residues | 3 |
Details | CARBOHYD: O-linked (HexNAc...) serine; by host => ECO:0000269|PubMed:32363391 |
Chain | Residue | Details |
A | VAL325 | |
B | VAL325 | |
C | VAL325 |
site_id | SWS_FT_FI10 |
Number of Residues | 3 |
Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | GLU603 | |
B | GLU603 | |
C | GLU603 |
site_id | SWS_FT_FI11 |
Number of Residues | 6 |
Details | CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269|PubMed:34732583 |
Chain | Residue | Details |
A | ILE676 | |
A | ALA678 | |
B | ILE676 | |
B | ALA678 | |
C | ILE676 | |
C | ALA678 |
site_id | SWS_FT_FI12 |
Number of Residues | 3 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
Chain | Residue | Details |
A | GLU1134 | |
B | GLU1134 | |
C | GLU1134 |