8D9W

beta-Arf1 homodimeric interface within AP-1, Arf1, Nef, MHC-I lattice on narrow tubes

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0001822	biological_process	kidney development
A	0005515	molecular_function	protein binding
A	0005765	cellular_component	lysosomal membrane
A	0005769	cellular_component	early endosome
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0006886	biological_process	intracellular protein transport
A	0007368	biological_process	determination of left/right symmetry
A	0007507	biological_process	heart development
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0016192	biological_process	vesicle-mediated transport
A	0019901	molecular_function	protein kinase binding
A	0030117	cellular_component	membrane coat
A	0030121	cellular_component	AP-1 adaptor complex
A	0030131	cellular_component	clathrin adaptor complex
A	0030276	molecular_function	clathrin binding
A	0030659	cellular_component	cytoplasmic vesicle membrane
A	0030665	cellular_component	clathrin-coated vesicle membrane
A	0031410	cellular_component	cytoplasmic vesicle
A	0032588	cellular_component	trans-Golgi network membrane
A	0043231	cellular_component	intracellular membrane-bounded organelle
A	0060155	biological_process	platelet dense granule organization
A	0110010	biological_process	basolateral protein secretion
A	1903232	biological_process	melanosome assembly
B	0000139	cellular_component	Golgi membrane
B	0001822	biological_process	kidney development
B	0005515	molecular_function	protein binding
B	0005765	cellular_component	lysosomal membrane
B	0005769	cellular_component	early endosome
B	0005794	cellular_component	Golgi apparatus
B	0005829	cellular_component	cytosol
B	0006886	biological_process	intracellular protein transport
B	0007368	biological_process	determination of left/right symmetry
B	0007507	biological_process	heart development
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane
B	0016192	biological_process	vesicle-mediated transport
B	0019901	molecular_function	protein kinase binding
B	0030117	cellular_component	membrane coat
B	0030121	cellular_component	AP-1 adaptor complex
B	0030131	cellular_component	clathrin adaptor complex
B	0030276	molecular_function	clathrin binding
B	0030659	cellular_component	cytoplasmic vesicle membrane
B	0030665	cellular_component	clathrin-coated vesicle membrane
B	0031410	cellular_component	cytoplasmic vesicle
B	0032588	cellular_component	trans-Golgi network membrane
B	0043231	cellular_component	intracellular membrane-bounded organelle
B	0060155	biological_process	platelet dense granule organization
B	0110010	biological_process	basolateral protein secretion
B	1903232	biological_process	melanosome assembly
D	0000139	cellular_component	Golgi membrane
D	0001822	biological_process	kidney development
D	0005515	molecular_function	protein binding
D	0005765	cellular_component	lysosomal membrane
D	0005769	cellular_component	early endosome
D	0005794	cellular_component	Golgi apparatus
D	0005829	cellular_component	cytosol
D	0006886	biological_process	intracellular protein transport
D	0007368	biological_process	determination of left/right symmetry
D	0007507	biological_process	heart development
D	0015031	biological_process	protein transport
D	0016020	cellular_component	membrane
D	0016192	biological_process	vesicle-mediated transport
D	0019901	molecular_function	protein kinase binding
D	0030117	cellular_component	membrane coat
D	0030121	cellular_component	AP-1 adaptor complex
D	0030131	cellular_component	clathrin adaptor complex
D	0030276	molecular_function	clathrin binding
D	0030659	cellular_component	cytoplasmic vesicle membrane
D	0030665	cellular_component	clathrin-coated vesicle membrane
D	0031410	cellular_component	cytoplasmic vesicle
D	0032588	cellular_component	trans-Golgi network membrane
D	0043231	cellular_component	intracellular membrane-bounded organelle
D	0060155	biological_process	platelet dense granule organization
D	0110010	biological_process	basolateral protein secretion
D	1903232	biological_process	melanosome assembly
E	0000139	cellular_component	Golgi membrane
E	0001822	biological_process	kidney development
E	0005515	molecular_function	protein binding
E	0005765	cellular_component	lysosomal membrane
E	0005769	cellular_component	early endosome
E	0005794	cellular_component	Golgi apparatus
E	0005829	cellular_component	cytosol
E	0006886	biological_process	intracellular protein transport
E	0007368	biological_process	determination of left/right symmetry
E	0007507	biological_process	heart development
E	0015031	biological_process	protein transport
E	0016020	cellular_component	membrane
E	0016192	biological_process	vesicle-mediated transport
E	0019901	molecular_function	protein kinase binding
E	0030117	cellular_component	membrane coat
E	0030121	cellular_component	AP-1 adaptor complex
E	0030131	cellular_component	clathrin adaptor complex
E	0030276	molecular_function	clathrin binding
E	0030659	cellular_component	cytoplasmic vesicle membrane
E	0030665	cellular_component	clathrin-coated vesicle membrane
E	0031410	cellular_component	cytoplasmic vesicle
E	0032588	cellular_component	trans-Golgi network membrane
E	0043231	cellular_component	intracellular membrane-bounded organelle
E	0060155	biological_process	platelet dense granule organization
E	0110010	biological_process	basolateral protein secretion
E	1903232	biological_process	melanosome assembly
F	0000139	cellular_component	Golgi membrane
F	0000287	molecular_function	magnesium ion binding
F	0002090	biological_process	regulation of receptor internalization
F	0003723	molecular_function	RNA binding
F	0003924	molecular_function	GTPase activity
F	0005515	molecular_function	protein binding
F	0005525	molecular_function	GTP binding
F	0005794	cellular_component	Golgi apparatus
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0005925	cellular_component	focal adhesion
F	0006878	biological_process	intracellular copper ion homeostasis
F	0006886	biological_process	intracellular protein transport
F	0012505	cellular_component	endomembrane system
F	0014069	cellular_component	postsynaptic density
F	0015031	biological_process	protein transport
F	0016020	cellular_component	membrane
F	0016192	biological_process	vesicle-mediated transport
F	0016787	molecular_function	hydrolase activity
F	0019904	molecular_function	protein domain specific binding
F	0030017	cellular_component	sarcomere
F	0031252	cellular_component	cell leading edge
F	0032991	cellular_component	protein-containing complex
F	0034315	biological_process	regulation of Arp2/3 complex-mediated actin nucleation
F	0043005	cellular_component	neuron projection
F	0045202	cellular_component	synapse
F	0060292	biological_process	long-term synaptic depression
F	0070062	cellular_component	extracellular exosome
F	0097061	biological_process	dendritic spine organization
F	0098586	biological_process	cellular response to virus
F	1990386	biological_process	mitotic cleavage furrow ingression
I	0000139	cellular_component	Golgi membrane
I	0000287	molecular_function	magnesium ion binding
I	0002090	biological_process	regulation of receptor internalization
I	0003723	molecular_function	RNA binding
I	0003924	molecular_function	GTPase activity
I	0005515	molecular_function	protein binding
I	0005525	molecular_function	GTP binding
I	0005794	cellular_component	Golgi apparatus
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0005925	cellular_component	focal adhesion
I	0006878	biological_process	intracellular copper ion homeostasis
I	0006886	biological_process	intracellular protein transport
I	0012505	cellular_component	endomembrane system
I	0014069	cellular_component	postsynaptic density
I	0015031	biological_process	protein transport
I	0016020	cellular_component	membrane
I	0016192	biological_process	vesicle-mediated transport
I	0016787	molecular_function	hydrolase activity
I	0019904	molecular_function	protein domain specific binding
I	0030017	cellular_component	sarcomere
I	0031252	cellular_component	cell leading edge
I	0032991	cellular_component	protein-containing complex
I	0034315	biological_process	regulation of Arp2/3 complex-mediated actin nucleation
I	0043005	cellular_component	neuron projection
I	0045202	cellular_component	synapse
I	0060292	biological_process	long-term synaptic depression
I	0070062	cellular_component	extracellular exosome
I	0097061	biological_process	dendritic spine organization
I	0098586	biological_process	cellular response to virus
I	1990386	biological_process	mitotic cleavage furrow ingression
K	0006886	biological_process	intracellular protein transport
K	0016192	biological_process	vesicle-mediated transport
K	0030117	cellular_component	membrane coat
M	0005515	molecular_function	protein binding
M	0005765	cellular_component	lysosomal membrane
M	0005769	cellular_component	early endosome
M	0005794	cellular_component	Golgi apparatus
M	0005802	cellular_component	trans-Golgi network
M	0005829	cellular_component	cytosol
M	0006886	biological_process	intracellular protein transport
M	0015031	biological_process	protein transport
M	0016020	cellular_component	membrane
M	0016192	biological_process	vesicle-mediated transport
M	0030121	cellular_component	AP-1 adaptor complex
M	0030131	cellular_component	clathrin adaptor complex
M	0030136	cellular_component	clathrin-coated vesicle
M	0030665	cellular_component	clathrin-coated vesicle membrane
M	0031410	cellular_component	cytoplasmic vesicle
M	0032438	biological_process	melanosome organization
M	0032588	cellular_component	trans-Golgi network membrane
M	0035615	molecular_function	clathrin adaptor activity
M	0035646	biological_process	endosome to melanosome transport
M	0043231	cellular_component	intracellular membrane-bounded organelle
M	0045202	cellular_component	synapse
M	0051649	biological_process	establishment of localization in cell
M	0060155	biological_process	platelet dense granule organization
M	1903232	biological_process	melanosome assembly
N	0005102	molecular_function	signaling receptor binding
N	0005515	molecular_function	protein binding
N	0005525	molecular_function	GTP binding
N	0005576	cellular_component	extracellular region
N	0006915	biological_process	apoptotic process
N	0016020	cellular_component	membrane
N	0017124	molecular_function	SH3 domain binding
N	0019049	biological_process	virus-mediated perturbation of host defense response
N	0019058	biological_process	viral life cycle
N	0019901	molecular_function	protein kinase binding
N	0020002	cellular_component	host cell plasma membrane
N	0031996	molecular_function	thioesterase binding
N	0033668	biological_process	symbiont-mediated suppression of host apoptosis
N	0039505	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II
N	0039521	biological_process	suppression by virus of host autophagy
N	0042288	molecular_function	MHC class I protein binding
N	0042609	molecular_function	CD4 receptor binding
N	0044177	cellular_component	host cell Golgi apparatus
N	0044178	cellular_component	host cell Golgi membrane
N	0044423	cellular_component	virion component
N	0045225	biological_process	negative regulation of CD4 production
N	0046776	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I
N	0050848	biological_process	regulation of calcium-mediated signaling
N	0051117	molecular_function	ATPase binding
N	0070206	biological_process	protein trimerization
N	0075528	biological_process	perturbation by virus of host immune response
O	0006886	biological_process	intracellular protein transport
O	0016192	biological_process	vesicle-mediated transport
O	0030117	cellular_component	membrane coat
U	0005102	molecular_function	signaling receptor binding
U	0005515	molecular_function	protein binding
U	0005525	molecular_function	GTP binding
U	0005576	cellular_component	extracellular region
U	0006915	biological_process	apoptotic process
U	0016020	cellular_component	membrane
U	0017124	molecular_function	SH3 domain binding
U	0019049	biological_process	virus-mediated perturbation of host defense response
U	0019058	biological_process	viral life cycle
U	0019901	molecular_function	protein kinase binding
U	0020002	cellular_component	host cell plasma membrane
U	0031996	molecular_function	thioesterase binding
U	0033668	biological_process	symbiont-mediated suppression of host apoptosis
U	0039505	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II
U	0039521	biological_process	suppression by virus of host autophagy
U	0042288	molecular_function	MHC class I protein binding
U	0042609	molecular_function	CD4 receptor binding
U	0044177	cellular_component	host cell Golgi apparatus
U	0044178	cellular_component	host cell Golgi membrane
U	0044423	cellular_component	virion component
U	0045225	biological_process	negative regulation of CD4 production
U	0046776	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I
U	0050848	biological_process	regulation of calcium-mediated signaling
U	0051117	molecular_function	ATPase binding
U	0070206	biological_process	protein trimerization
U	0075528	biological_process	perturbation by virus of host immune response
V	0005102	molecular_function	signaling receptor binding
V	0005515	molecular_function	protein binding
V	0005525	molecular_function	GTP binding
V	0005576	cellular_component	extracellular region
V	0006915	biological_process	apoptotic process
V	0016020	cellular_component	membrane
V	0017124	molecular_function	SH3 domain binding
V	0019049	biological_process	virus-mediated perturbation of host defense response
V	0019058	biological_process	viral life cycle
V	0019901	molecular_function	protein kinase binding
V	0020002	cellular_component	host cell plasma membrane
V	0031996	molecular_function	thioesterase binding
V	0033668	biological_process	symbiont-mediated suppression of host apoptosis
V	0039505	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II
V	0039521	biological_process	suppression by virus of host autophagy
V	0042288	molecular_function	MHC class I protein binding
V	0042609	molecular_function	CD4 receptor binding
V	0044177	cellular_component	host cell Golgi apparatus
V	0044178	cellular_component	host cell Golgi membrane
V	0044423	cellular_component	virion component
V	0045225	biological_process	negative regulation of CD4 production
V	0046776	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I
V	0050848	biological_process	regulation of calcium-mediated signaling
V	0051117	molecular_function	ATPase binding
V	0070206	biological_process	protein trimerization
V	0075528	biological_process	perturbation by virus of host immune response
X	0005515	molecular_function	protein binding
X	0005765	cellular_component	lysosomal membrane
X	0005769	cellular_component	early endosome
X	0005794	cellular_component	Golgi apparatus
X	0005802	cellular_component	trans-Golgi network
X	0005829	cellular_component	cytosol
X	0006886	biological_process	intracellular protein transport
X	0015031	biological_process	protein transport
X	0016020	cellular_component	membrane
X	0016192	biological_process	vesicle-mediated transport
X	0030121	cellular_component	AP-1 adaptor complex
X	0030131	cellular_component	clathrin adaptor complex
X	0030136	cellular_component	clathrin-coated vesicle
X	0030665	cellular_component	clathrin-coated vesicle membrane
X	0031410	cellular_component	cytoplasmic vesicle
X	0032438	biological_process	melanosome organization
X	0032588	cellular_component	trans-Golgi network membrane
X	0035615	molecular_function	clathrin adaptor activity
X	0035646	biological_process	endosome to melanosome transport
X	0043231	cellular_component	intracellular membrane-bounded organelle
X	0045202	cellular_component	synapse
X	0051649	biological_process	establishment of localization in cell
X	0060155	biological_process	platelet dense granule organization
X	1903232	biological_process	melanosome assembly
Y	0006955	biological_process	immune response
Y	0019882	biological_process	antigen processing and presentation
Z	0005515	molecular_function	protein binding
Z	0005765	cellular_component	lysosomal membrane
Z	0005769	cellular_component	early endosome
Z	0005794	cellular_component	Golgi apparatus
Z	0005802	cellular_component	trans-Golgi network
Z	0005829	cellular_component	cytosol
Z	0006886	biological_process	intracellular protein transport
Z	0015031	biological_process	protein transport
Z	0016020	cellular_component	membrane
Z	0016192	biological_process	vesicle-mediated transport
Z	0030121	cellular_component	AP-1 adaptor complex
Z	0030131	cellular_component	clathrin adaptor complex
Z	0030136	cellular_component	clathrin-coated vesicle
Z	0030665	cellular_component	clathrin-coated vesicle membrane
Z	0031410	cellular_component	cytoplasmic vesicle
Z	0032438	biological_process	melanosome organization
Z	0032588	cellular_component	trans-Golgi network membrane
Z	0035615	molecular_function	clathrin adaptor activity
Z	0035646	biological_process	endosome to melanosome transport
Z	0043231	cellular_component	intracellular membrane-bounded organelle
Z	0045202	cellular_component	synapse
Z	0051649	biological_process	establishment of localization in cell
Z	0060155	biological_process	platelet dense granule organization
Z	1903232	biological_process	melanosome assembly
a	0005515	molecular_function	protein binding
a	0005765	cellular_component	lysosomal membrane
a	0005769	cellular_component	early endosome
a	0005794	cellular_component	Golgi apparatus
a	0005802	cellular_component	trans-Golgi network
a	0005829	cellular_component	cytosol
a	0006886	biological_process	intracellular protein transport
a	0015031	biological_process	protein transport
a	0016020	cellular_component	membrane
a	0016192	biological_process	vesicle-mediated transport
a	0030121	cellular_component	AP-1 adaptor complex
a	0030131	cellular_component	clathrin adaptor complex
a	0030136	cellular_component	clathrin-coated vesicle
a	0030665	cellular_component	clathrin-coated vesicle membrane
a	0031410	cellular_component	cytoplasmic vesicle
a	0032438	biological_process	melanosome organization
a	0032588	cellular_component	trans-Golgi network membrane
a	0035615	molecular_function	clathrin adaptor activity
a	0035646	biological_process	endosome to melanosome transport
a	0043231	cellular_component	intracellular membrane-bounded organelle
a	0045202	cellular_component	synapse
a	0051649	biological_process	establishment of localization in cell
a	0060155	biological_process	platelet dense granule organization
a	1903232	biological_process	melanosome assembly
d	0005102	molecular_function	signaling receptor binding
d	0005515	molecular_function	protein binding
d	0005525	molecular_function	GTP binding
d	0005576	cellular_component	extracellular region
d	0006915	biological_process	apoptotic process
d	0016020	cellular_component	membrane
d	0017124	molecular_function	SH3 domain binding
d	0019049	biological_process	virus-mediated perturbation of host defense response
d	0019058	biological_process	viral life cycle
d	0019901	molecular_function	protein kinase binding
d	0020002	cellular_component	host cell plasma membrane
d	0031996	molecular_function	thioesterase binding
d	0033668	biological_process	symbiont-mediated suppression of host apoptosis
d	0039505	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II
d	0039521	biological_process	suppression by virus of host autophagy
d	0042288	molecular_function	MHC class I protein binding
d	0042609	molecular_function	CD4 receptor binding
d	0044177	cellular_component	host cell Golgi apparatus
d	0044178	cellular_component	host cell Golgi membrane
d	0044423	cellular_component	virion component
d	0045225	biological_process	negative regulation of CD4 production
d	0046776	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I
d	0050848	biological_process	regulation of calcium-mediated signaling
d	0051117	molecular_function	ATPase binding
d	0070206	biological_process	protein trimerization
d	0075528	biological_process	perturbation by virus of host immune response
e	0000139	cellular_component	Golgi membrane
e	0005515	molecular_function	protein binding
e	0005765	cellular_component	lysosomal membrane
e	0005769	cellular_component	early endosome
e	0005794	cellular_component	Golgi apparatus
e	0005829	cellular_component	cytosol
e	0005905	cellular_component	clathrin-coated pit
e	0006605	biological_process	protein targeting
e	0006886	biological_process	intracellular protein transport
e	0015031	biological_process	protein transport
e	0016192	biological_process	vesicle-mediated transport
e	0030117	cellular_component	membrane coat
e	0030121	cellular_component	AP-1 adaptor complex
e	0030659	cellular_component	cytoplasmic vesicle membrane
e	0031410	cellular_component	cytoplasmic vesicle
e	0032588	cellular_component	trans-Golgi network membrane
e	0035615	molecular_function	clathrin adaptor activity
e	0043231	cellular_component	intracellular membrane-bounded organelle
e	0060155	biological_process	platelet dense granule organization
e	1903232	biological_process	melanosome assembly
f	0000139	cellular_component	Golgi membrane
f	0005515	molecular_function	protein binding
f	0005765	cellular_component	lysosomal membrane
f	0005769	cellular_component	early endosome
f	0005794	cellular_component	Golgi apparatus
f	0005829	cellular_component	cytosol
f	0005905	cellular_component	clathrin-coated pit
f	0006605	biological_process	protein targeting
f	0006886	biological_process	intracellular protein transport
f	0015031	biological_process	protein transport
f	0016192	biological_process	vesicle-mediated transport
f	0030117	cellular_component	membrane coat
f	0030121	cellular_component	AP-1 adaptor complex
f	0030659	cellular_component	cytoplasmic vesicle membrane
f	0031410	cellular_component	cytoplasmic vesicle
f	0032588	cellular_component	trans-Golgi network membrane
f	0035615	molecular_function	clathrin adaptor activity
f	0043231	cellular_component	intracellular membrane-bounded organelle
f	0060155	biological_process	platelet dense granule organization
f	1903232	biological_process	melanosome assembly
j	0006955	biological_process	immune response
j	0019882	biological_process	antigen processing and presentation

Functional Information from PROSITE/UniProt

site_id	PS00989
Number of Residues	11
Details	CLAT_ADAPTOR_S Clathrin adaptor complexes small chain signature. LVYKryasLYF

Chain	Residue	Details
e	LEU57-PHE67

---

site_id	PS00990
Number of Residues	21
Details	CLAT_ADAPTOR_M_1 Clathrin adaptor complexes medium chain signature 1. VSWRse.GikYrkNeVFLDVIE

Chain	Residue	Details
M	VAL157-GLU177

---

site_id	PS00991
Number of Residues	15
Details	CLAT_ADAPTOR_M_2 Clathrin adaptor complexes medium chain signature 2. IsFIPPdGeFeLmsY

Chain	Residue	Details
M	ILE253-TYR267

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:7990966, ECO:0007744|PDB:1HUR

Chain	Residue	Details
F	GLY24
I	GLY24
Z	SER2
a	SER2
j	SER348
j	GLY354
j	SER355
j	SER357

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:14690595, ECO:0000269|PubMed:15308674, ECO:0000269|PubMed:7990966, ECO:0000269|Ref.34, ECO:0007744|PDB:1HUR, ECO:0007744|PDB:1RE0, ECO:0007744|PDB:1U81, ECO:0007744|PDB:3O47

Chain	Residue	Details
F	ASN126
I	ASN126
X	THR152
X	THR154
Z	THR152
Z	THR154
a	THR152
a	THR154

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:15308674, ECO:0000269|PubMed:7990966, ECO:0000269|Ref.34, ECO:0007744|PDB:1HUR, ECO:0007744|PDB:1RE0, ECO:0007744|PDB:3O47

Chain	Residue	Details
F	ALA160
I	ALA160
Z	THR223
a	THR223

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: N-acetylglycine; alternate => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895

Chain	Residue	Details
F	GLY2
I	GLY2

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	LIPID: N-myristoyl glycine; alternate => ECO:0000269|PubMed:20213681, ECO:0000269|PubMed:23535599, ECO:0000269|PubMed:25255805, ECO:0000269|PubMed:25807930

Chain	Residue	Details
F	GLY2
I	GLY2

---