8CDD

PfRH5-PfCyRPA-PfRIPR complex from Plasmodium falciparum bound to antibody Cy.003

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005886	cellular_component	plasma membrane
A	0016020	cellular_component	membrane
A	0020002	cellular_component	host cell plasma membrane
A	0020009	cellular_component	microneme
A	0031410	cellular_component	cytoplasmic vesicle
A	0032991	cellular_component	protein-containing complex
A	0033644	cellular_component	host cell membrane
A	0034494	cellular_component	microneme lumen
A	0043655	cellular_component	host extracellular space
A	0044409	biological_process	symbiont entry into host
B	0004308	molecular_function	exo-alpha-sialidase activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005886	cellular_component	plasma membrane
B	0020002	cellular_component	host cell plasma membrane
B	0020009	cellular_component	microneme
B	0031410	cellular_component	cytoplasmic vesicle
B	0032991	cellular_component	protein-containing complex
B	0034494	cellular_component	microneme lumen
B	0043655	cellular_component	host extracellular space
B	0044409	biological_process	symbiont entry into host
B	0045177	cellular_component	apical part of cell
B	0046658	cellular_component	obsolete anchored component of plasma membrane
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005923	cellular_component	bicellular tight junction
C	0008201	molecular_function	heparin binding
C	0016020	cellular_component	membrane
C	0020002	cellular_component	host cell plasma membrane
C	0020008	cellular_component	rhoptry
C	0031410	cellular_component	cytoplasmic vesicle
C	0032991	cellular_component	protein-containing complex
C	0033644	cellular_component	host cell membrane
C	0034591	cellular_component	rhoptry lumen
C	0043655	cellular_component	host extracellular space
C	0044409	biological_process	symbiont entry into host
C	0044650	biological_process	adhesion of symbiont to host cell
C	0045177	cellular_component	apical part of cell
C	0046789	molecular_function	host cell surface receptor binding

Functional Information from PROSITE/UniProt

site_id	PS01186
Number of Residues	16
Details	EGF_2 EGF-like domain signature 2. CfCdnPYiskygnklC

Chain	Residue	Details
A	CYS659-CYS674
A	CYS701-CYS714

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
D	TYR210-HIS216
E	TYR226-HIS232

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Cleavage => ECO:0000269|PubMed:28186186

Chain	Residue	Details
C	LYS140
A	GLN646
A	GLN964
A	GLN1021
B	ASN322
B	ASN338
A	ASN303
A	GLN334
A	GLN480
A	GLN498
A	GLN506
A	GLN526

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
C	ASN38
C	ASN297

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:25296023, ECO:0007744|PDB:4WAT

Chain	Residue	Details
C	ASN214

---