Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8CA7

Omadacycline and spectinomycin bound to the 30S ribosomal subunit head

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000028	biological_process	ribosomal small subunit assembly
C	0002181	biological_process	cytoplasmic translation
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
C	0003729	molecular_function	mRNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0019843	molecular_function	rRNA binding
C	0022627	cellular_component	cytosolic small ribosomal subunit
C	1990904	cellular_component	ribonucleoprotein complex
E	0000028	biological_process	ribosomal small subunit assembly
E	0002181	biological_process	cytoplasmic translation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0015935	cellular_component	small ribosomal subunit
E	0019843	molecular_function	rRNA binding
E	0022627	cellular_component	cytosolic small ribosomal subunit
E	0043229	cellular_component	intracellular organelle
E	0046677	biological_process	response to antibiotic
E	1990145	biological_process	maintenance of translational fidelity
E	1990904	cellular_component	ribonucleoprotein complex
G	0000028	biological_process	ribosomal small subunit assembly
G	0000049	molecular_function	tRNA binding
G	0002181	biological_process	cytoplasmic translation
G	0003723	molecular_function	RNA binding
G	0003729	molecular_function	mRNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0015935	cellular_component	small ribosomal subunit
G	0016020	cellular_component	membrane
G	0017148	biological_process	negative regulation of translation
G	0019843	molecular_function	rRNA binding
G	0022627	cellular_component	cytosolic small ribosomal subunit
G	1990904	cellular_component	ribonucleoprotein complex
I	0000049	molecular_function	tRNA binding
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0022627	cellular_component	cytosolic small ribosomal subunit
I	0043232	cellular_component	intracellular non-membrane-bounded organelle
I	1990904	cellular_component	ribonucleoprotein complex
J	0000049	molecular_function	tRNA binding
J	0001072	molecular_function	transcription antitermination factor activity, RNA binding
J	0002181	biological_process	cytoplasmic translation
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0008023	cellular_component	transcription elongation factor complex
J	0015935	cellular_component	small ribosomal subunit
J	0022627	cellular_component	cytosolic small ribosomal subunit
J	0031564	biological_process	transcription antitermination
J	0032784	biological_process	regulation of DNA-templated transcription elongation
J	0042254	biological_process	ribosome biogenesis
J	1990904	cellular_component	ribonucleoprotein complex
M	0000049	molecular_function	tRNA binding
M	0002181	biological_process	cytoplasmic translation
M	0003676	molecular_function	nucleic acid binding
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0015935	cellular_component	small ribosomal subunit
M	0019843	molecular_function	rRNA binding
M	0022627	cellular_component	cytosolic small ribosomal subunit
M	1990904	cellular_component	ribonucleoprotein complex
N	0000028	biological_process	ribosomal small subunit assembly
N	0000049	molecular_function	tRNA binding
N	0002181	biological_process	cytoplasmic translation
N	0003735	molecular_function	structural constituent of ribosome
N	0005737	cellular_component	cytoplasm
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0015935	cellular_component	small ribosomal subunit
N	0019843	molecular_function	rRNA binding
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	0043229	cellular_component	intracellular organelle
N	1990904	cellular_component	ribonucleoprotein complex
S	0000028	biological_process	ribosomal small subunit assembly
S	0000049	molecular_function	tRNA binding
S	0002181	biological_process	cytoplasmic translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015935	cellular_component	small ribosomal subunit
S	0019843	molecular_function	rRNA binding
S	0022627	cellular_component	cytosolic small ribosomal subunit
S	0043229	cellular_component	intracellular organelle
S	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00548
Number of Residues	35
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewyreGrVplHt..LradIDyntseahTtyGviG

Chain	Residue	Details
C	ALA163-GLY197

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRifsFtAltVVGDgn.GrVGfGygkar.EVpa.AI

Chain	Residue	Details
E	GLY28-ILE60

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGisGQagAirhGiTRAL

Chain	Residue	Details
I	GLY69-LEU87

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGRqhvpvfVtdemVGhkLGEFapT

Chain	Residue	Details
S	ASN53-THR77

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. SeLlakFVnilmvdGKKstaesIVysA

Chain	Residue	Details
G	SER20-ALA46

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkrtGAqvrGPIpLPT

Chain	Residue	Details
J	ALA29-THR44

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CrqtgrphgflrkFGLSRiKVR

Chain	Residue	Details
N	ARG63-ARG85

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. PdhkhavialTsiYGVGKTRSkAILaAAG

Chain	Residue	Details
M	PRO10-GLY38

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ

Chain	Residue	Details
M	ARG87-GLN100

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0000269\|PubMed:363452

Chain	Residue	Details
E	ALA2

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)