8C8H

Cryo EM structure of the vaccinia complete RNA polymerase complex lacking the capping enzyme

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0001055	molecular_function	RNA polymerase II activity
A	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
A	0006366	biological_process	transcription by RNA polymerase II
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0039695	biological_process	DNA-templated viral transcription
A	0044423	cellular_component	virion component
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0001054	molecular_function	RNA polymerase I activity
B	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
B	0006360	biological_process	transcription by RNA polymerase I
B	0016779	molecular_function	nucleotidyltransferase activity
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0044423	cellular_component	virion component
B	0046872	molecular_function	metal ion binding
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0034062	molecular_function	5'-3' RNA polymerase activity
C	0044423	cellular_component	virion component
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0034062	molecular_function	5'-3' RNA polymerase activity
E	0039695	biological_process	DNA-templated viral transcription
E	0044423	cellular_component	virion component
F	0000428	cellular_component	DNA-directed RNA polymerase complex
F	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
F	0016779	molecular_function	nucleotidyltransferase activity
F	0034062	molecular_function	5'-3' RNA polymerase activity
F	0044423	cellular_component	virion component
G	0000428	cellular_component	DNA-directed RNA polymerase complex
G	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
G	0016779	molecular_function	nucleotidyltransferase activity
G	0034062	molecular_function	5'-3' RNA polymerase activity
G	0044423	cellular_component	virion component
I	0006353	biological_process	DNA-templated transcription termination
I	0006355	biological_process	regulation of DNA-templated transcription
I	0039695	biological_process	DNA-templated viral transcription
I	0044423	cellular_component	virion component
J	0000428	cellular_component	DNA-directed RNA polymerase complex
J	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
J	0016779	molecular_function	nucleotidyltransferase activity
J	0034062	molecular_function	5'-3' RNA polymerase activity
J	0044423	cellular_component	virion component
K	0003677	molecular_function	DNA binding
K	0044423	cellular_component	virion component
Q	0044423	cellular_component	virion component
R	0044423	cellular_component	virion component
S	0000428	cellular_component	DNA-directed RNA polymerase complex
S	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
S	0016779	molecular_function	nucleotidyltransferase activity
S	0030430	cellular_component	host cell cytoplasm
S	0034062	molecular_function	5'-3' RNA polymerase activity
S	0039695	biological_process	DNA-templated viral transcription
S	0044423	cellular_component	virion component
S	0046872	molecular_function	metal ion binding
Y	0003677	molecular_function	DNA binding
Y	0005524	molecular_function	ATP binding
Y	0006338	biological_process	chromatin remodeling
Y	0016787	molecular_function	hydrolase activity
Y	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
Y	0044423	cellular_component	virion component

Functional Information from PROSITE/UniProt

site_id	PS00466
Number of Residues	36
Details	ZF_TFIIS_1 Zinc finger TFIIS-type signature. CpnCksrnttpmmIQTRAaDEPplvrhaCrd...CkqhF

Chain	Residue	Details
S	CYS159-PHE194

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site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKFTTrTSQKGT

Chain	Residue	Details
B	GLY880-THR892

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	ZN_FING: TFIIS-type => ECO:0000255|PROSITE-ProRule:PRU00472

Chain	Residue	Details
S	TYR155-LYS195

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00472

Chain	Residue	Details
S	CYS159
S	CYS162
S	CYS187
S	CYS190

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