7ZV9

Crystal structure of FLT3 in complex with a monomeric FLT3 Ligand variant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005125	molecular_function	cytokine activity
A	0016020	cellular_component	membrane
C	0005125	molecular_function	cytokine activity
C	0016020	cellular_component	membrane
E	0005125	molecular_function	cytokine activity
E	0016020	cellular_component	membrane
G	0005125	molecular_function	cytokine activity
G	0016020	cellular_component	membrane
I	0005125	molecular_function	cytokine activity
I	0016020	cellular_component	membrane
K	0005125	molecular_function	cytokine activity
K	0016020	cellular_component	membrane
M	0005125	molecular_function	cytokine activity
M	0016020	cellular_component	membrane
O	0005125	molecular_function	cytokine activity
O	0016020	cellular_component	membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	56
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21389326

Chain	Residue	Details
B	ASN43
D	ASN151
D	ASN306
D	ASN323
D	ASN351
D	ASN354
F	ASN43
F	ASN100
F	ASN152
F	ASN306
F	ASN323
B	ASN100
F	ASN351
F	ASN354
H	ASN43
H	ASN100
H	ASN151
H	ASN306
H	ASN323
H	ASN351
H	ASN354
J	ASN43
B	ASN151
J	ASN100
J	ASN151
J	ASN306
J	ASN323
J	ASN351
J	ASN354
L	ASN43
L	ASN100
L	ASN151
L	ASN306
B	ASN306
L	ASN323
L	ASN351
L	ASN354
N	ASN43
N	ASN100
N	ASN151
N	ASN306
N	ASN323
N	ASN351
N	ASN354
B	ASN323
P	ASN43
P	ASN100
P	ASN151
P	ASN306
P	ASN323
P	ASN351
P	ASN354
B	ASN351
B	ASN354
D	ASN43
D	ASN100

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site_id	SWS_FT_FI2
Number of Residues	16
Details	CARBOHYD: N-linked (GlcNAc...) asparagine

Chain	Residue	Details
B	ASN473
J	ASN502
L	ASN473
L	ASN502
N	ASN473
N	ASN502
P	ASN473
P	ASN502
B	ASN502
D	ASN473
D	ASN502
F	ASN473
F	ASN502
H	ASN473
H	ASN502
J	ASN473

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site_id	SWS_FT_FI3
Number of Residues	8
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
B	ASN541
D	ASN541
F	ASN541
H	ASN541
J	ASN541
L	ASN541
N	ASN541
P	ASN541

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