7X5D
Crystal Structure of the K316C mutant of Human Lamin A/C Coil 2 (residues 244-340)
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | SITE: Heptad change of phase |
| Chain | Residue | Details |
| A | THR266 | |
| A | GLU330 | |
| B | THR266 | |
| B | GLU330 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Stutter => ECO:0000305 |
| Chain | Residue | Details |
| A | ASP325 | |
| B | ASP325 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P48678 |
| Chain | Residue | Details |
| A | LYS260 | |
| B | LYS260 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS270 | |
| A | LYS311 | |
| B | LYS270 | |
| B | LYS311 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| A | SER277 | |
| B | SER277 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by ATR => ECO:0000269|PubMed:37832547 |
| Chain | Residue | Details |
| A | SER282 | |
| B | SER282 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER301 | |
| B | SER301 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER307 | |
| B | SER307 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS260 | |
| A | LYS270 | |
| B | LYS260 | |
| B | LYS270 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS311 | |
| B | LYS311 |
