7W6X

Crystal structure of E. coli RseP in complex with batimastat

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004175	molecular_function	endopeptidase activity
A	0004222	molecular_function	metalloendopeptidase activity
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0008237	molecular_function	metallopeptidase activity
A	0016020	cellular_component	membrane
A	0036460	biological_process	cellular response to cell envelope stress
A	0043856	molecular_function	anti-sigma factor antagonist activity
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00142
Number of Residues	10
Details	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. ITVHEFGHFW

Chain	Residue	Details
A	ILE19-TRP28

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	FME1-VAL21
A	GLY104-VAL124
A	VAL376-PHE396
A	ILE430-LEU450

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site_id	SWS_FT_FI2
Number of Residues	113
Details	TOPO_DOM: Periplasmic => ECO:0000305|PubMed:11750129

Chain	Residue	Details
A	HIS22-ALA103
A	PRO397-ARG429

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site_id	SWS_FT_FI3
Number of Residues	250
Details	TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:11750129

Chain	Residue	Details
A	PRO125-GLY375

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site_id	SWS_FT_FI4
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000305

Chain	Residue	Details
A	GLU23

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site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A	HIS22

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site_id	SWS_FT_FI6
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10095

Chain	Residue	Details
A	HIS26

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