7W1E

Crystal structure of Klebsiella pneumoniae K1 capsule-specific polysaccharide lyase in complex with products

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016829	molecular_function	lyase activity
A	0046718	biological_process	symbiont entry into host cell
A	0098015	cellular_component	virus tail
A	0098671	biological_process	adhesion receptor-mediated virion attachment to host cell
A	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
A	0098996	biological_process	symbiont entry into host cell via disruption of host cell glycocalyx
B	0016829	molecular_function	lyase activity
B	0046718	biological_process	symbiont entry into host cell
B	0098015	cellular_component	virus tail
B	0098671	biological_process	adhesion receptor-mediated virion attachment to host cell
B	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
B	0098996	biological_process	symbiont entry into host cell via disruption of host cell glycocalyx
C	0016829	molecular_function	lyase activity
C	0046718	biological_process	symbiont entry into host cell
C	0098015	cellular_component	virus tail
C	0098671	biological_process	adhesion receptor-mediated virion attachment to host cell
C	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
C	0098996	biological_process	symbiont entry into host cell via disruption of host cell glycocalyx
D	0016829	molecular_function	lyase activity
D	0046718	biological_process	symbiont entry into host cell
D	0098015	cellular_component	virus tail
D	0098671	biological_process	adhesion receptor-mediated virion attachment to host cell
D	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
D	0098996	biological_process	symbiont entry into host cell via disruption of host cell glycocalyx
E	0016829	molecular_function	lyase activity
E	0046718	biological_process	symbiont entry into host cell
E	0098015	cellular_component	virus tail
E	0098671	biological_process	adhesion receptor-mediated virion attachment to host cell
E	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
E	0098996	biological_process	symbiont entry into host cell via disruption of host cell glycocalyx
F	0016829	molecular_function	lyase activity
F	0046718	biological_process	symbiont entry into host cell
F	0098015	cellular_component	virus tail
F	0098671	biological_process	adhesion receptor-mediated virion attachment to host cell
F	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
F	0098996	biological_process	symbiont entry into host cell via disruption of host cell glycocalyx

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	BINDING: BINDING => ECO:0000269|PubMed:35130876

Chain	Residue	Details
A	GLN130
A	LYS177
A	ASN217
A	LYS291
A	GLU314
A	ASN339
A	TRP340
A	ARG378
B	GLN130
B	LYS177
B	ASN217
B	LYS291
B	GLU314
B	ASN339
B	TRP340
B	ARG378
C	GLN130
C	LYS177
C	ASN217
C	LYS291
C	GLU314
C	ASN339
C	TRP340
C	ARG378
D	GLN130
D	LYS177
D	ASN217
D	LYS291
D	GLU314
D	ASN339
D	TRP340
D	ARG378
E	GLN130
E	LYS177
E	ASN217
E	LYS291
E	GLU314
E	ASN339
E	TRP340
E	ARG378
F	GLN130
F	LYS177
F	ASN217
F	LYS291
F	GLU314
F	ASN339
F	TRP340
F	ARG378

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	SITE: Important for catalysis => ECO:0000269|PubMed:35130876

Chain	Residue	Details
A	TYR311
A	HIS373
A	ARG397
B	TYR311
B	HIS373
B	ARG397
C	TYR311
C	HIS373
C	ARG397
D	TYR311
D	HIS373
D	ARG397
E	TYR311
E	HIS373
E	ARG397
F	TYR311
F	HIS373
F	ARG397

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	SITE: Important for the adsorption and infectivity of phage => ECO:0000269|PubMed:35130876

Chain	Residue	Details
A	ARG472
B	ARG472
C	ARG472
D	ARG472
E	ARG472
F	ARG472

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