7VCI

Structure of Xenopus laevis NPC nuclear ring asymmetric unit

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005643	cellular_component	nuclear pore
A	0005829	cellular_component	cytosol
A	0006406	biological_process	mRNA export from nucleus
A	0006606	biological_process	protein import into nucleus
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0017056	molecular_function	structural constituent of nuclear pore
A	0031080	cellular_component	nuclear pore outer ring
A	0031965	cellular_component	nuclear membrane
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0051028	biological_process	mRNA transport
A	0072006	biological_process	nephron development
B	0005829	cellular_component	cytosol
B	0031080	cellular_component	nuclear pore outer ring
C	0000775	cellular_component	chromosome, centromeric region
C	0000776	cellular_component	kinetochore
C	0005198	molecular_function	structural molecule activity
C	0005634	cellular_component	nucleus
C	0005643	cellular_component	nuclear pore
C	0005694	cellular_component	chromosome
C	0005764	cellular_component	lysosome
C	0005765	cellular_component	lysosomal membrane
C	0005829	cellular_component	cytosol
C	0006999	biological_process	nuclear pore organization
C	0007059	biological_process	chromosome segregation
C	0007080	biological_process	mitotic metaphase chromosome alignment
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
C	0031080	cellular_component	nuclear pore outer ring
C	0031669	biological_process	cellular response to nutrient levels
C	0034198	biological_process	cellular response to amino acid starvation
C	0035859	cellular_component	Seh1-associated complex
C	0051028	biological_process	mRNA transport
C	0051301	biological_process	cell division
C	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
C	0061700	cellular_component	GATOR2 complex
C	1904263	biological_process	positive regulation of TORC1 signaling
E	0005829	cellular_component	cytosol
E	0031080	cellular_component	nuclear pore outer ring
G	0005198	molecular_function	structural molecule activity
G	0005643	cellular_component	nuclear pore
G	0005764	cellular_component	lysosome
G	0005765	cellular_component	lysosomal membrane
G	0005829	cellular_component	cytosol
G	0006606	biological_process	protein import into nucleus
G	0015031	biological_process	protein transport
G	0030127	cellular_component	COPII vesicle coat
G	0031080	cellular_component	nuclear pore outer ring
G	0032008	biological_process	positive regulation of TOR signaling
G	0032527	biological_process	protein exit from endoplasmic reticulum
G	0051028	biological_process	mRNA transport
G	0090114	biological_process	COPII-coated vesicle budding
H	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
H	0005634	cellular_component	nucleus
H	0005635	cellular_component	nuclear envelope
H	0005643	cellular_component	nuclear pore
H	0005829	cellular_component	cytosol
H	0006406	biological_process	mRNA export from nucleus
H	0006606	biological_process	protein import into nucleus
H	0015031	biological_process	protein transport
H	0016020	cellular_component	membrane
H	0017056	molecular_function	structural constituent of nuclear pore
H	0031080	cellular_component	nuclear pore outer ring
H	0031965	cellular_component	nuclear membrane
H	0051028	biological_process	mRNA transport
I	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
I	0005634	cellular_component	nucleus
I	0005643	cellular_component	nuclear pore
I	0005829	cellular_component	cytosol
I	0006606	biological_process	protein import into nucleus
I	0016973	biological_process	poly(A)+ mRNA export from nucleus
I	0017056	molecular_function	structural constituent of nuclear pore
I	0031080	cellular_component	nuclear pore outer ring
J	0005634	cellular_component	nucleus
J	0005643	cellular_component	nuclear pore
J	0005829	cellular_component	cytosol
J	0006406	biological_process	mRNA export from nucleus
J	0006606	biological_process	protein import into nucleus
J	0015031	biological_process	protein transport
J	0016020	cellular_component	membrane
J	0017056	molecular_function	structural constituent of nuclear pore
J	0031080	cellular_component	nuclear pore outer ring
J	0031965	cellular_component	nuclear membrane
J	0045893	biological_process	positive regulation of DNA-templated transcription
J	0051028	biological_process	mRNA transport
J	0072006	biological_process	nephron development
K	0005829	cellular_component	cytosol
K	0031080	cellular_component	nuclear pore outer ring
L	0000775	cellular_component	chromosome, centromeric region
L	0000776	cellular_component	kinetochore
L	0005198	molecular_function	structural molecule activity
L	0005634	cellular_component	nucleus
L	0005643	cellular_component	nuclear pore
L	0005694	cellular_component	chromosome
L	0005764	cellular_component	lysosome
L	0005765	cellular_component	lysosomal membrane
L	0005829	cellular_component	cytosol
L	0006999	biological_process	nuclear pore organization
L	0007059	biological_process	chromosome segregation
L	0007080	biological_process	mitotic metaphase chromosome alignment
L	0015031	biological_process	protein transport
L	0016020	cellular_component	membrane
L	0031080	cellular_component	nuclear pore outer ring
L	0031669	biological_process	cellular response to nutrient levels
L	0034198	biological_process	cellular response to amino acid starvation
L	0035859	cellular_component	Seh1-associated complex
L	0051028	biological_process	mRNA transport
L	0051301	biological_process	cell division
L	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
L	0061700	cellular_component	GATOR2 complex
L	1904263	biological_process	positive regulation of TORC1 signaling
N	0005829	cellular_component	cytosol
N	0031080	cellular_component	nuclear pore outer ring
P	0005198	molecular_function	structural molecule activity
P	0005643	cellular_component	nuclear pore
P	0005764	cellular_component	lysosome
P	0005765	cellular_component	lysosomal membrane
P	0005829	cellular_component	cytosol
P	0006606	biological_process	protein import into nucleus
P	0015031	biological_process	protein transport
P	0030127	cellular_component	COPII vesicle coat
P	0031080	cellular_component	nuclear pore outer ring
P	0032008	biological_process	positive regulation of TOR signaling
P	0032527	biological_process	protein exit from endoplasmic reticulum
P	0051028	biological_process	mRNA transport
P	0090114	biological_process	COPII-coated vesicle budding
Q	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
Q	0005634	cellular_component	nucleus
Q	0005635	cellular_component	nuclear envelope
Q	0005643	cellular_component	nuclear pore
Q	0005829	cellular_component	cytosol
Q	0006406	biological_process	mRNA export from nucleus
Q	0006606	biological_process	protein import into nucleus
Q	0015031	biological_process	protein transport
Q	0016020	cellular_component	membrane
Q	0017056	molecular_function	structural constituent of nuclear pore
Q	0031080	cellular_component	nuclear pore outer ring
Q	0031965	cellular_component	nuclear membrane
Q	0051028	biological_process	mRNA transport
R	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
R	0005634	cellular_component	nucleus
R	0005643	cellular_component	nuclear pore
R	0005829	cellular_component	cytosol
R	0006606	biological_process	protein import into nucleus
R	0016973	biological_process	poly(A)+ mRNA export from nucleus
R	0017056	molecular_function	structural constituent of nuclear pore
R	0031080	cellular_component	nuclear pore outer ring
S	0005634	cellular_component	nucleus
S	0005643	cellular_component	nuclear pore
S	0006913	biological_process	nucleocytoplasmic transport
S	0006999	biological_process	nuclear pore organization
S	0017056	molecular_function	structural constituent of nuclear pore
S	0044611	cellular_component	nuclear pore inner ring
T	0003677	molecular_function	DNA binding
T	0005634	cellular_component	nucleus
T	0005643	cellular_component	nuclear pore
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0015031	biological_process	protein transport
T	0051028	biological_process	mRNA transport
U	0005634	cellular_component	nucleus
U	0005643	cellular_component	nuclear pore
U	0005829	cellular_component	cytosol
U	0006606	biological_process	protein import into nucleus
U	0015031	biological_process	protein transport
U	0016020	cellular_component	membrane
U	0016973	biological_process	poly(A)+ mRNA export from nucleus
U	0017056	molecular_function	structural constituent of nuclear pore
U	0031965	cellular_component	nuclear membrane
U	0034399	cellular_component	nuclear periphery
U	0051028	biological_process	mRNA transport
U	0051292	biological_process	nuclear pore complex assembly

Functional Information from PROSITE/UniProt

site_id	PS00616
Number of Residues	15
Details	HIS_ACID_PHOSPHAT_1 Histidine acid phosphatases phosphohistidine signature. LlyAfhIyRHNyRkA

Chain	Residue	Details
D	LEU1082-ALA1096

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site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. VATGgqDgMLCIWDV

Chain	Residue	Details
B	VAL230-VAL244
E	ILE140-LEU154

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	DNA_BIND: A.T hook => ECO:0000269|PubMed:18596237

Chain	Residue	Details
T	SER2329-LYS2341

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