Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7UCJ

Mammalian 80S translation initiation complex with mRNA and Harringtonine

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003735	molecular_function	structural constituent of ribosome
A	0005840	cellular_component	ribosome
A	0006412	biological_process	translation
AA	0003735	molecular_function	structural constituent of ribosome
AA	0005840	cellular_component	ribosome
AA	0006412	biological_process	translation
AA	0015935	cellular_component	small ribosomal subunit
Aa	0003735	molecular_function	structural constituent of ribosome
Aa	0005840	cellular_component	ribosome
Aa	0006412	biological_process	translation
B	0003723	molecular_function	RNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0005634	cellular_component	nucleus
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0022625	cellular_component	cytosolic large ribosomal subunit
B	1990904	cellular_component	ribonucleoprotein complex
BB	0003735	molecular_function	structural constituent of ribosome
BB	0005840	cellular_component	ribosome
BB	0006412	biological_process	translation
Bb	0000028	biological_process	ribosomal small subunit assembly
Bb	0003723	molecular_function	RNA binding
Bb	0003735	molecular_function	structural constituent of ribosome
Bb	0005634	cellular_component	nucleus
Bb	0005730	cellular_component	nucleolus
Bb	0005737	cellular_component	cytoplasm
Bb	0005840	cellular_component	ribosome
Bb	0006412	biological_process	translation
Bb	0022626	cellular_component	cytosolic ribosome
Bb	0022627	cellular_component	cytosolic small ribosomal subunit
Bb	0046872	molecular_function	metal ion binding
Bb	1990904	cellular_component	ribonucleoprotein complex
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0022625	cellular_component	cytosolic large ribosomal subunit
C	1990904	cellular_component	ribonucleoprotein complex
CC	0003723	molecular_function	RNA binding
CC	0003735	molecular_function	structural constituent of ribosome
CC	0005840	cellular_component	ribosome
CC	0006412	biological_process	translation
CC	0015935	cellular_component	small ribosomal subunit
Cc	0000028	biological_process	ribosomal small subunit assembly
Cc	0002181	biological_process	cytoplasmic translation
Cc	0003735	molecular_function	structural constituent of ribosome
Cc	0005634	cellular_component	nucleus
Cc	0005730	cellular_component	nucleolus
Cc	0005737	cellular_component	cytoplasm
Cc	0005783	cellular_component	endoplasmic reticulum
Cc	0005791	cellular_component	rough endoplasmic reticulum
Cc	0005829	cellular_component	cytosol
Cc	0005840	cellular_component	ribosome
Cc	0006364	biological_process	rRNA processing
Cc	0006412	biological_process	translation
Cc	0022626	cellular_component	cytosolic ribosome
Cc	0022627	cellular_component	cytosolic small ribosomal subunit
Cc	0030490	biological_process	maturation of SSU-rRNA
Cc	0032040	cellular_component	small-subunit processome
Cc	0042254	biological_process	ribosome biogenesis
Cc	0042274	biological_process	ribosomal small subunit biogenesis
Cc	0045202	cellular_component	synapse
Cc	1990904	cellular_component	ribonucleoprotein complex
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0008097	molecular_function	5S rRNA binding
DD	0003677	molecular_function	DNA binding
DD	0003723	molecular_function	RNA binding
DD	0003735	molecular_function	structural constituent of ribosome
DD	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
DD	0005634	cellular_component	nucleus
DD	0005730	cellular_component	nucleolus
DD	0005737	cellular_component	cytoplasm
DD	0005739	cellular_component	mitochondrion
DD	0005743	cellular_component	mitochondrial inner membrane
DD	0005819	cellular_component	spindle
DD	0005840	cellular_component	ribosome
DD	0005856	cellular_component	cytoskeleton
DD	0006281	biological_process	DNA repair
DD	0006412	biological_process	translation
DD	0006417	biological_process	regulation of translation
DD	0006915	biological_process	apoptotic process
DD	0015935	cellular_component	small ribosomal subunit
DD	0016829	molecular_function	lyase activity
DD	0022626	cellular_component	cytosolic ribosome
DD	0022627	cellular_component	cytosolic small ribosomal subunit
DD	0031334	biological_process	positive regulation of protein-containing complex assembly
DD	0045202	cellular_component	synapse
DD	0051301	biological_process	cell division
DD	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DD	1990904	cellular_component	ribonucleoprotein complex
DD	2001235	biological_process	positive regulation of apoptotic signaling pathway
Dd	0003735	molecular_function	structural constituent of ribosome
Dd	0005737	cellular_component	cytoplasm
Dd	0005783	cellular_component	endoplasmic reticulum
Dd	0005791	cellular_component	rough endoplasmic reticulum
Dd	0005829	cellular_component	cytosol
Dd	0005840	cellular_component	ribosome
Dd	0006412	biological_process	translation
Dd	0008270	molecular_function	zinc ion binding
Dd	0022626	cellular_component	cytosolic ribosome
Dd	0022627	cellular_component	cytosolic small ribosomal subunit
Dd	0046872	molecular_function	metal ion binding
Dd	1990904	cellular_component	ribonucleoprotein complex
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
EE	0003723	molecular_function	RNA binding
EE	0003735	molecular_function	structural constituent of ribosome
EE	0005840	cellular_component	ribosome
EE	0006412	biological_process	translation
EE	0019843	molecular_function	rRNA binding
EE	0022627	cellular_component	cytosolic small ribosomal subunit
EE	1990904	cellular_component	ribonucleoprotein complex
Ee	0003735	molecular_function	structural constituent of ribosome
Ee	0005840	cellular_component	ribosome
Ee	0006412	biological_process	translation
F	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F	0003735	molecular_function	structural constituent of ribosome
F	0022625	cellular_component	cytosolic large ribosomal subunit
FF	0000028	biological_process	ribosomal small subunit assembly
FF	0003723	molecular_function	RNA binding
FF	0003729	molecular_function	mRNA binding
FF	0003735	molecular_function	structural constituent of ribosome
FF	0005634	cellular_component	nucleus
FF	0005730	cellular_component	nucleolus
FF	0005737	cellular_component	cytoplasm
FF	0005840	cellular_component	ribosome
FF	0006412	biological_process	translation
FF	0015935	cellular_component	small ribosomal subunit
FF	0019843	molecular_function	rRNA binding
FF	0022626	cellular_component	cytosolic ribosome
FF	0022627	cellular_component	cytosolic small ribosomal subunit
FF	1990904	cellular_component	ribonucleoprotein complex
G	0042254	biological_process	ribosome biogenesis
G	1990904	cellular_component	ribonucleoprotein complex
GG	0003735	molecular_function	structural constituent of ribosome
GG	0005840	cellular_component	ribosome
GG	0006412	biological_process	translation
Gg	0001891	cellular_component	phagocytic cup
Gg	0001934	biological_process	positive regulation of protein phosphorylation
Gg	0005080	molecular_function	protein kinase C binding
Gg	0005634	cellular_component	nucleus
Gg	0005737	cellular_component	cytoplasm
Gg	0005829	cellular_component	cytosol
Gg	0005840	cellular_component	ribosome
Gg	0005886	cellular_component	plasma membrane
Gg	0006417	biological_process	regulation of translation
Gg	0006915	biological_process	apoptotic process
Gg	0007369	biological_process	gastrulation
Gg	0030425	cellular_component	dendrite
Gg	0042995	cellular_component	cell projection
Gg	0043022	molecular_function	ribosome binding
Gg	0043204	cellular_component	perikaryon
Gg	0045182	molecular_function	translation regulator activity
Gg	0048471	cellular_component	perinuclear region of cytoplasm
Gg	0048511	biological_process	rhythmic process
Gg	0072344	biological_process	rescue of stalled ribosome
Gg	1990904	cellular_component	ribonucleoprotein complex
H	0002181	biological_process	cytoplasmic translation
H	0003735	molecular_function	structural constituent of ribosome
H	0005737	cellular_component	cytoplasm
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0019843	molecular_function	rRNA binding
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	1990904	cellular_component	ribonucleoprotein complex
HH	0003735	molecular_function	structural constituent of ribosome
HH	0005840	cellular_component	ribosome
HH	0006412	biological_process	translation
I	0003735	molecular_function	structural constituent of ribosome
I	0005737	cellular_component	cytoplasm
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0006417	biological_process	regulation of translation
I	0022625	cellular_component	cytosolic large ribosomal subunit
I	1990904	cellular_component	ribonucleoprotein complex
II	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
II	0003735	molecular_function	structural constituent of ribosome
II	0005634	cellular_component	nucleus
II	0005730	cellular_component	nucleolus
II	0005737	cellular_component	cytoplasm
II	0005840	cellular_component	ribosome
II	0006412	biological_process	translation
II	0016020	cellular_component	membrane
II	0022626	cellular_component	cytosolic ribosome
II	0022627	cellular_component	cytosolic small ribosomal subunit
II	1990904	cellular_component	ribonucleoprotein complex
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005634	cellular_component	nucleus
J	0005730	cellular_component	nucleolus
J	0005737	cellular_component	cytoplasm
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0019843	molecular_function	rRNA binding
J	0022625	cellular_component	cytosolic large ribosomal subunit
J	1990904	cellular_component	ribonucleoprotein complex
JJ	0003723	molecular_function	RNA binding
JJ	0003735	molecular_function	structural constituent of ribosome
JJ	0005634	cellular_component	nucleus
JJ	0005730	cellular_component	nucleolus
JJ	0005737	cellular_component	cytoplasm
JJ	0005840	cellular_component	ribosome
JJ	0006412	biological_process	translation
JJ	0015935	cellular_component	small ribosomal subunit
JJ	0019843	molecular_function	rRNA binding
JJ	0022626	cellular_component	cytosolic ribosome
JJ	0022627	cellular_component	cytosolic small ribosomal subunit
JJ	0042274	biological_process	ribosomal small subunit biogenesis
JJ	1990904	cellular_component	ribonucleoprotein complex
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
LL	0003735	molecular_function	structural constituent of ribosome
LL	0005634	cellular_component	nucleus
LL	0005730	cellular_component	nucleolus
LL	0005737	cellular_component	cytoplasm
LL	0005840	cellular_component	ribosome
LL	0006412	biological_process	translation
LL	0019843	molecular_function	rRNA binding
LL	0022626	cellular_component	cytosolic ribosome
LL	0022627	cellular_component	cytosolic small ribosomal subunit
LL	1990904	cellular_component	ribonucleoprotein complex
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
N	0002181	biological_process	cytoplasmic translation
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005737	cellular_component	cytoplasm
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	1990904	cellular_component	ribonucleoprotein complex
NN	0003735	molecular_function	structural constituent of ribosome
NN	0005634	cellular_component	nucleus
NN	0005730	cellular_component	nucleolus
NN	0005737	cellular_component	cytoplasm
NN	0005840	cellular_component	ribosome
NN	0006412	biological_process	translation
NN	0022626	cellular_component	cytosolic ribosome
NN	0022627	cellular_component	cytosolic small ribosomal subunit
NN	0070181	molecular_function	small ribosomal subunit rRNA binding
NN	1990904	cellular_component	ribonucleoprotein complex
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0015934	cellular_component	large ribosomal subunit
OO	0003735	molecular_function	structural constituent of ribosome
OO	0005840	cellular_component	ribosome
OO	0006412	biological_process	translation
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0015934	cellular_component	large ribosomal subunit
PP	0003723	molecular_function	RNA binding
PP	0003735	molecular_function	structural constituent of ribosome
PP	0005840	cellular_component	ribosome
PP	0006412	biological_process	translation
PP	0015935	cellular_component	small ribosomal subunit
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
QQ	0003735	molecular_function	structural constituent of ribosome
QQ	0005840	cellular_component	ribosome
QQ	0006412	biological_process	translation
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005737	cellular_component	cytoplasm
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0022625	cellular_component	cytosolic large ribosomal subunit
R	1990904	cellular_component	ribonucleoprotein complex
RR	0003735	molecular_function	structural constituent of ribosome
RR	0005634	cellular_component	nucleus
RR	0005730	cellular_component	nucleolus
RR	0005737	cellular_component	cytoplasm
RR	0005840	cellular_component	ribosome
RR	0006412	biological_process	translation
RR	0022626	cellular_component	cytosolic ribosome
RR	1990904	cellular_component	ribonucleoprotein complex
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
SS	0003676	molecular_function	nucleic acid binding
SS	0003723	molecular_function	RNA binding
SS	0003735	molecular_function	structural constituent of ribosome
SS	0005737	cellular_component	cytoplasm
SS	0005829	cellular_component	cytosol
SS	0005840	cellular_component	ribosome
SS	0006412	biological_process	translation
SS	0015935	cellular_component	small ribosomal subunit
SS	0019843	molecular_function	rRNA binding
SS	0022626	cellular_component	cytosolic ribosome
SS	1990904	cellular_component	ribonucleoprotein complex
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005783	cellular_component	endoplasmic reticulum
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0022625	cellular_component	cytosolic large ribosomal subunit
T	1990904	cellular_component	ribonucleoprotein complex
TT	0003735	molecular_function	structural constituent of ribosome
TT	0005840	cellular_component	ribosome
TT	0006412	biological_process	translation
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
UU	0003723	molecular_function	RNA binding
UU	0003735	molecular_function	structural constituent of ribosome
UU	0005840	cellular_component	ribosome
UU	0006412	biological_process	translation
UU	0015935	cellular_component	small ribosomal subunit
V	0000122	biological_process	negative regulation of transcription by RNA polymerase II
V	0001223	molecular_function	transcription coactivator binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005654	cellular_component	nucleoplasm
V	0005730	cellular_component	nucleolus
V	0005737	cellular_component	cytoplasm
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0008284	biological_process	positive regulation of cell population proliferation
V	0010628	biological_process	positive regulation of gene expression
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	0022626	cellular_component	cytosolic ribosome
V	0031625	molecular_function	ubiquitin protein ligase binding
V	0032986	biological_process	protein-DNA complex disassembly
V	0032991	cellular_component	protein-containing complex
V	0045202	cellular_component	synapse
V	0050821	biological_process	protein stabilization
V	0070180	molecular_function	large ribosomal subunit rRNA binding
V	0070314	biological_process	G1 to G0 transition
V	0072717	biological_process	cellular response to actinomycin D
V	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
V	1903450	biological_process	regulation of G1 to G0 transition
V	1990904	cellular_component	ribonucleoprotein complex
V	1990948	molecular_function	ubiquitin ligase inhibitor activity
V	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
VV	0003735	molecular_function	structural constituent of ribosome
VV	0005840	cellular_component	ribosome
VV	0006412	biological_process	translation
WW	0003735	molecular_function	structural constituent of ribosome
WW	0005634	cellular_component	nucleus
WW	0005730	cellular_component	nucleolus
WW	0005737	cellular_component	cytoplasm
WW	0005840	cellular_component	ribosome
WW	0006412	biological_process	translation
WW	0022626	cellular_component	cytosolic ribosome
WW	0022627	cellular_component	cytosolic small ribosomal subunit
WW	1990904	cellular_component	ribonucleoprotein complex
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0019843	molecular_function	rRNA binding
XX	0003735	molecular_function	structural constituent of ribosome
XX	0005634	cellular_component	nucleus
XX	0005730	cellular_component	nucleolus
XX	0005737	cellular_component	cytoplasm
XX	0005783	cellular_component	endoplasmic reticulum
XX	0005791	cellular_component	rough endoplasmic reticulum
XX	0005829	cellular_component	cytosol
XX	0005840	cellular_component	ribosome
XX	0006412	biological_process	translation
XX	0015935	cellular_component	small ribosomal subunit
XX	0022626	cellular_component	cytosolic ribosome
XX	0022627	cellular_component	cytosolic small ribosomal subunit
XX	1990904	cellular_component	ribonucleoprotein complex
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005654	cellular_component	nucleoplasm
Y	0005730	cellular_component	nucleolus
Y	0005737	cellular_component	cytoplasm
Y	0005840	cellular_component	ribosome
Y	0006364	biological_process	rRNA processing
Y	0006412	biological_process	translation
Y	0006977	biological_process	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
Y	0015934	cellular_component	large ribosomal subunit
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	0022626	cellular_component	cytosolic ribosome
Y	0034644	biological_process	cellular response to UV
Y	0042273	biological_process	ribosomal large subunit biogenesis
Y	0045202	cellular_component	synapse
Y	0045727	biological_process	positive regulation of translation
Y	0048027	molecular_function	mRNA 5'-UTR binding
Y	0071479	biological_process	cellular response to ionizing radiation
Y	0071480	biological_process	cellular response to gamma radiation
Y	1902164	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
Y	1902167	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Y	1904803	biological_process	regulation of translation involved in cellular response to UV
Y	1990904	cellular_component	ribonucleoprotein complex
YY	0003735	molecular_function	structural constituent of ribosome
YY	0005840	cellular_component	ribosome
YY	0006412	biological_process	translation
YY	1990904	cellular_component	ribonucleoprotein complex
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005654	cellular_component	nucleoplasm
Z	0005730	cellular_component	nucleolus
Z	0005737	cellular_component	cytoplasm
Z	0005783	cellular_component	endoplasmic reticulum
Z	0005791	cellular_component	rough endoplasmic reticulum
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0006364	biological_process	rRNA processing
Z	0006412	biological_process	translation
Z	0022625	cellular_component	cytosolic large ribosomal subunit
Z	0022626	cellular_component	cytosolic ribosome
Z	1990904	cellular_component	ribonucleoprotein complex
a	0003735	molecular_function	structural constituent of ribosome
a	0005737	cellular_component	cytoplasm
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
a	0015934	cellular_component	large ribosomal subunit
a	0022625	cellular_component	cytosolic large ribosomal subunit
a	1990904	cellular_component	ribonucleoprotein complex
b	0003735	molecular_function	structural constituent of ribosome
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
c	0003723	molecular_function	RNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
e	0003735	molecular_function	structural constituent of ribosome
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
f	0000049	molecular_function	tRNA binding
f	0002181	biological_process	cytoplasmic translation
f	0003735	molecular_function	structural constituent of ribosome
f	0005737	cellular_component	cytoplasm
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	0022625	cellular_component	cytosolic large ribosomal subunit
f	0042273	biological_process	ribosomal large subunit biogenesis
f	1990904	cellular_component	ribonucleoprotein complex
g	0003735	molecular_function	structural constituent of ribosome
g	0005737	cellular_component	cytoplasm
g	0005783	cellular_component	endoplasmic reticulum
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0022625	cellular_component	cytosolic large ribosomal subunit
g	1990904	cellular_component	ribonucleoprotein complex
h	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
h	0003729	molecular_function	mRNA binding
h	0003735	molecular_function	structural constituent of ribosome
h	0005737	cellular_component	cytoplasm
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
h	0022625	cellular_component	cytosolic large ribosomal subunit
h	1990904	cellular_component	ribonucleoprotein complex
i	0003735	molecular_function	structural constituent of ribosome
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
j	0003735	molecular_function	structural constituent of ribosome
j	0005840	cellular_component	ribosome
j	0006412	biological_process	translation
k	0003735	molecular_function	structural constituent of ribosome
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
l	0003735	molecular_function	structural constituent of ribosome
l	0005840	cellular_component	ribosome
l	0006412	biological_process	translation
l	0022625	cellular_component	cytosolic large ribosomal subunit
l	1990904	cellular_component	ribonucleoprotein complex
m	0003735	molecular_function	structural constituent of ribosome
m	0005840	cellular_component	ribosome
m	0006412	biological_process	translation
n	0003735	molecular_function	structural constituent of ribosome
n	0005737	cellular_component	cytoplasm
n	0005840	cellular_component	ribosome
n	0006412	biological_process	translation
n	1990904	cellular_component	ribonucleoprotein complex
o	0003735	molecular_function	structural constituent of ribosome
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
p	0003735	molecular_function	structural constituent of ribosome
p	0005737	cellular_component	cytoplasm
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
p	0046872	molecular_function	metal ion binding
p	1990904	cellular_component	ribonucleoprotein complex
r	0003735	molecular_function	structural constituent of ribosome
r	0005737	cellular_component	cytoplasm
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation
r	0022625	cellular_component	cytosolic large ribosomal subunit
r	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI

Chain	Residue	Details
V	ALA79-ILE105

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV

Chain	Residue	Details
X	LYS134-VAL149

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR

Chain	Residue	Details
l	LYS30-ARG46

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsMMmhgrnnGKKlmtvrIVkhA

Chain	Residue	Details
FF	GLU70-ALA96

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GfiVLTTSaGIMdheeAR

Chain	Residue	Details
WW	GLY100-ARG117

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPiPSD

Chain	Residue	Details
OO	LEU116-ASP138

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
XX	LYS60-ARG67

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgEcRPLS

Chain	Residue	Details
LL	GLY123-SER135

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLGEFsiT

Chain	Residue	Details
PP	ASN98-THR122

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT

Chain	Residue	Details
J	LEU40-THR56

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQiyAirqSiSKAL

Chain	Residue	Details
QQ	GLY74-LEU92

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT

Chain	Residue	Details
UU	ALA43-THR58

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
NN	VAL98-TYR128

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL

Chain	Residue	Details
P	ARG126-LEU150

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE

Chain	Residue	Details
A	PRO197-GLU208

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR

Chain	Residue	Details
B	PHE211-ARG234

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIkgvG

Chain	Residue	Details
a	LYS110-GLY141

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP

Chain	Residue	Details
R	GLN7-PRO26

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR

Chain	Residue	Details
Dd	ARG22-ARG44

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRVAaPkhWmLdK

Chain	Residue	Details
EE	HIS8-LYS22

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGmIYDSldyakknE

Chain	Residue	Details
YY	PHE64-GLU86

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG

Chain	Residue	Details
DD	ALA147-GLY183

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM

Chain	Residue	Details
GG	ILE52-MET63

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV

Chain	Residue	Details
h	LYS43-VAL57

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG

Chain	Residue	Details
e	PHE20-GLY40

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvAIGDyn.GhVGlGvkcsk.EVat.AI

Chain	Residue	Details
CC	GLY119-ILE151

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRrVLQaLE

Chain	Residue	Details
TT	PRO89-GLU108

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVFKlglAkSihhARvLI

Chain	Residue	Details
JJ	LEU106-ILE130

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLrQifNgTfvklnkasinMLriVepYI

Chain	Residue	Details
F	VAL107-ILE139

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ

Chain	Residue	Details
SS	ARG121-GLN134

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL

Chain	Residue	Details
Gg	ALA78-LEU92
Gg	ILE120-THR134
Gg	ILE165-LEU179
Gg	CYS207-LEU221

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV

Chain	Residue	Details
C	GLY15-VAL22

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK

Chain	Residue	Details
H	GLN163-LYS184

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqsLKmiRqGkaKlVIL

Chain	Residue	Details
c	SER24-LEU48

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH

Chain	Residue	Details
RR	ILE41-HIS56

site_id	PS00733
Number of Residues	8
Details	RIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH

Chain	Residue	Details
Aa	TYR73-HIS80

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG

Chain	Residue	Details
O	VAL84-GLY107

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH

Chain	Residue	Details
C	ASN116-HIS142

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. RLvRELEKKFSgKH

Chain	Residue	Details
HH	ARG78-HIS91

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
Cc	GLU60-LEU68

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VlKFLAAGTHLG

Chain	Residue	Details
AA	VAL15-GLY26

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLVVtDpraDhqpLtEasyvNLP

Chain	Residue	Details
AA	PRO119-PRO143

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLsIiDpG

Chain	Residue	Details
c	GLU80-GLY100

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
VV	LEU11-ALA19

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGykIyPGhGrrYaRtD

Chain	Residue	Details
W	PHE8-ASP25

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG

Chain	Residue	Details
j	GLY4-GLY23

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciLkGKarLG

Chain	Residue	Details
G	CYS227-GLY244

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG

Chain	Residue	Details
L	ARG71-GLY85

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP

Chain	Residue	Details
f	GLY72-PRO93

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM

Chain	Residue	Details
Q	LYS49-MET66

site_id	PS01107
Number of Residues	12
Details	RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF

Chain	Residue	Details
Z	GLY125-PHE136

site_id	PS01108
Number of Residues	19
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV

Chain	Residue	Details
Y	ASP52-VAL70

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG

Chain	Residue	Details
d	VAL62-GLY76

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TaSnKtrlsRTPGN

Chain	Residue	Details
g	THR15-ASN28

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgCykittvFShAqtvvlCvgCStvLcqPtG

Chain	Residue	Details
Bb	LYS36-GLY68

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K

Chain	Residue	Details
E	ASN185-LYS203

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG

Chain	Residue	Details
T	GLY37-GLY62

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLRleC

Chain	Residue	Details
o	LYS61-CYS72

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK

Chain	Residue	Details
i	PRO52-LYS62

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVfEvSLaDL

Chain	Residue	Details
BB	LEU62-LEU74

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RrkTGGkrkpy.HkKrKyELG

Chain	Residue	Details
II	ARG11-GLY30

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG

Chain	Residue	Details
N	ASP46-GLY69

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPqGtvARV

Chain	Residue	Details
I	ALA108-VAL129

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P39023

Chain	Residue	Details
B	SER13
B	SER304
Gg	THR96
Gg	THR277
DD	LEU204

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:P27659

Chain	Residue	Details
B	LYS136
B	LYS373
Bb	CYS56
Bb	CYS59

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Tele-methylhistidine => ECO:0000250\|UniProtKB:P39023

Chain	Residue	Details
B	HIS245
ZZ	TYR65
OO	ASP46
OO	GLY89

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000250\|UniProtKB:P27659

Chain	Residue	Details
B	LYS286
SS	LYS94
SS	LYS106

site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000250\|UniProtKB:P39023

Chain	Residue	Details
B	LYS294
B	LYS366
Gg	SER279

site_id	SWS_FT_FI6
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250\|UniProtKB:P39023

Chain	Residue	Details
B	LYS39
NN	LYS43
B	LYS224
B	LYS226
B	LYS386
B	LYS393

site_id	SWS_FT_FI7
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0000250\|UniProtKB:P39023

Chain	Residue	Details
B	LYS286
B	LYS366

site_id	SWS_FT_FI8
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate => ECO:0000250\|UniProtKB:P39023

Chain	Residue	Details
B	LYS294

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)