7RYT

Crystal structure of Mycobacterium tuberculosis acetylated Homoserine transacetylase with Coenzyme A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004414	molecular_function	homoserine O-acetyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0009058	biological_process	biosynthetic process
A	0009086	biological_process	methionine biosynthetic process
A	0009092	biological_process	homoserine metabolic process
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0003824	molecular_function	catalytic activity
B	0004414	molecular_function	homoserine O-acetyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0009058	biological_process	biosynthetic process
B	0009086	biological_process	methionine biosynthetic process
B	0009092	biological_process	homoserine metabolic process
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0003824	molecular_function	catalytic activity
C	0004414	molecular_function	homoserine O-acetyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0005886	cellular_component	plasma membrane
C	0009058	biological_process	biosynthetic process
C	0009086	biological_process	methionine biosynthetic process
C	0009092	biological_process	homoserine metabolic process
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0003824	molecular_function	catalytic activity
D	0004414	molecular_function	homoserine O-acetyltransferase activity
D	0005737	cellular_component	cytoplasm
D	0005886	cellular_component	plasma membrane
D	0009058	biological_process	biosynthetic process
D	0009086	biological_process	methionine biosynthetic process
D	0009092	biological_process	homoserine metabolic process
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
E	0003824	molecular_function	catalytic activity
E	0004414	molecular_function	homoserine O-acetyltransferase activity
E	0005737	cellular_component	cytoplasm
E	0005886	cellular_component	plasma membrane
E	0009058	biological_process	biosynthetic process
E	0009086	biological_process	methionine biosynthetic process
E	0009092	biological_process	homoserine metabolic process
E	0016746	molecular_function	acyltransferase activity
E	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
F	0003824	molecular_function	catalytic activity
F	0004414	molecular_function	homoserine O-acetyltransferase activity
F	0005737	cellular_component	cytoplasm
F	0005886	cellular_component	plasma membrane
F	0009058	biological_process	biosynthetic process
F	0009086	biological_process	methionine biosynthetic process
F	0009092	biological_process	homoserine metabolic process
F	0016746	molecular_function	acyltransferase activity
F	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_00296

Chain	Residue	Details
A	OAS157
B	OAS157
C	OAS157
D	OAS157
E	OAS157
F	OAS157

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site_id	SWS_FT_FI2
Number of Residues	12
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00296

Chain	Residue	Details
A	ASP320
A	HIS350
B	ASP320
B	HIS350
C	ASP320
C	HIS350
D	ASP320
D	HIS350
E	ASP320
E	HIS350
F	ASP320
F	HIS350

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site_id	SWS_FT_FI3
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00296

Chain	Residue	Details
A	ARG227
A	ASP351
B	ARG227
B	ASP351
C	ARG227
C	ASP351
D	ARG227
D	ASP351
E	ARG227
E	ASP351
F	ARG227
F	ASP351

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