7R3D

CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT N151G, L259V COMPLEXED WITH FE, NADH, AND GLYCEROL (Absence of Nicotinamide ring)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0000166	molecular_function	nucleotide binding
AAA	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
AAA	0005829	cellular_component	cytosol
AAA	0006004	biological_process	fucose metabolic process
AAA	0008198	molecular_function	ferrous iron binding
AAA	0008912	molecular_function	lactaldehyde reductase activity
AAA	0016491	molecular_function	oxidoreductase activity
AAA	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
AAA	0019301	biological_process	rhamnose catabolic process
AAA	0019317	biological_process	fucose catabolic process
AAA	0042355	biological_process	L-fucose catabolic process
AAA	0042803	molecular_function	protein homodimerization activity
AAA	0042846	biological_process	glycol catabolic process
AAA	0046872	molecular_function	metal ion binding
AAA	0051143	biological_process	propanediol metabolic process
AAA	0052660	molecular_function	R-lactaldehyde reductase activity
AAA	0052661	molecular_function	S-lactaldehyde reductase activity
BBB	0000166	molecular_function	nucleotide binding
BBB	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
BBB	0005829	cellular_component	cytosol
BBB	0006004	biological_process	fucose metabolic process
BBB	0008198	molecular_function	ferrous iron binding
BBB	0008912	molecular_function	lactaldehyde reductase activity
BBB	0016491	molecular_function	oxidoreductase activity
BBB	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
BBB	0019301	biological_process	rhamnose catabolic process
BBB	0019317	biological_process	fucose catabolic process
BBB	0042355	biological_process	L-fucose catabolic process
BBB	0042803	molecular_function	protein homodimerization activity
BBB	0042846	biological_process	glycol catabolic process
BBB	0046872	molecular_function	metal ion binding
BBB	0051143	biological_process	propanediol metabolic process
BBB	0052660	molecular_function	R-lactaldehyde reductase activity
BBB	0052661	molecular_function	S-lactaldehyde reductase activity

Functional Information from PROSITE/UniProt

site_id	PS00060
Number of Residues	21
Details	ADH_IRON_2 Iron-containing alcohol dehydrogenases signature 2. GlVHgmAHpLGAfynTpHGvA

Chain	Residue	Details
AAA	GLY260-ALA280

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site_id	PS00913
Number of Residues	29
Details	ADH_IRON_1 Iron-containing alcohol dehydrogenases signature 1. AFiDadmmdgmPpalkAaTgvDALthaiE

Chain	Residue	Details
AAA	ALA175-GLU203

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0007744|PDB:2BI4, ECO:0007744|PDB:2BL4, ECO:0007744|PDB:5BR4

Chain	Residue	Details
AAA	ASP39
BBB	LYS162
BBB	MET181
BBB	HIS277
AAA	GLY98
AAA	THR140
AAA	LYS162
AAA	MET181
AAA	HIS277
BBB	ASP39
BBB	GLY98
BBB	THR140

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0007744|PDB:2BI4, ECO:0007744|PDB:2BL4

Chain	Residue	Details
AAA	ASN71
BBB	ASN71
AAA	ASP342
BBB	ASP342

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
AAA	GLY151
BBB	GLY151

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site_id	SWS_FT_FI4
Number of Residues	6
Details	BINDING: BINDING => ECO:0007744|PDB:1RRM, ECO:0007744|PDB:2BI4, ECO:0007744|PDB:2BL4, ECO:0007744|PDB:5BR4

Chain	Residue	Details
AAA	ASP196
AAA	HIS200
AAA	HIS263
BBB	ASP196
BBB	HIS200
BBB	HIS263

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site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0007744|PDB:2BL4, ECO:0007744|PDB:5BR4

Chain	Residue	Details
AAA	THR149
BBB	THR149

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