7QUI
Crystal structure of the N-terminal domain of Siglec-8 in complex with sulfonamide sialoside analogue
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27357658, ECO:0007744|PDB:2N7B |
| Chain | Residue | Details |
| B | TYR23 | |
| B | ARG72 | |
| B | ARG125 | |
| B | SER134 | |
| A | TYR23 | |
| A | ARG72 | |
| A | ARG125 | |
| A | SER134 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Indispensable role in 6'-sulfo sialyl-Lewis X => ECO:0000269|PubMed:27357658 |
| Chain | Residue | Details |
| B | ARG125 | |
| A | ARG125 |
