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7PKO

CryoEM structure of Rotavirus NSP2

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003723molecular_functionRNA binding
A0004550molecular_functionnucleoside diphosphate kinase activity
A0005524molecular_functionATP binding
A0016787molecular_functionhydrolase activity
A0016817molecular_functionhydrolase activity, acting on acid anhydrides
A0017111molecular_functionribonucleoside triphosphate phosphatase activity
A0019079biological_processviral genome replication
A0030430cellular_componenthost cell cytoplasm
A0046872molecular_functionmetal ion binding
B0000166molecular_functionnucleotide binding
B0003723molecular_functionRNA binding
B0004550molecular_functionnucleoside diphosphate kinase activity
B0005524molecular_functionATP binding
B0016787molecular_functionhydrolase activity
B0016817molecular_functionhydrolase activity, acting on acid anhydrides
B0017111molecular_functionribonucleoside triphosphate phosphatase activity
B0019079biological_processviral genome replication
B0030430cellular_componenthost cell cytoplasm
B0046872molecular_functionmetal ion binding
C0000166molecular_functionnucleotide binding
C0003723molecular_functionRNA binding
C0004550molecular_functionnucleoside diphosphate kinase activity
C0005524molecular_functionATP binding
C0016787molecular_functionhydrolase activity
C0016817molecular_functionhydrolase activity, acting on acid anhydrides
C0017111molecular_functionribonucleoside triphosphate phosphatase activity
C0019079biological_processviral genome replication
C0030430cellular_componenthost cell cytoplasm
C0046872molecular_functionmetal ion binding
D0000166molecular_functionnucleotide binding
D0003723molecular_functionRNA binding
D0004550molecular_functionnucleoside diphosphate kinase activity
D0005524molecular_functionATP binding
D0016787molecular_functionhydrolase activity
D0016817molecular_functionhydrolase activity, acting on acid anhydrides
D0017111molecular_functionribonucleoside triphosphate phosphatase activity
D0019079biological_processviral genome replication
D0030430cellular_componenthost cell cytoplasm
D0046872molecular_functionmetal ion binding
E0000166molecular_functionnucleotide binding
E0003723molecular_functionRNA binding
E0004550molecular_functionnucleoside diphosphate kinase activity
E0005524molecular_functionATP binding
E0016787molecular_functionhydrolase activity
E0016817molecular_functionhydrolase activity, acting on acid anhydrides
E0017111molecular_functionribonucleoside triphosphate phosphatase activity
E0019079biological_processviral genome replication
E0030430cellular_componenthost cell cytoplasm
E0046872molecular_functionmetal ion binding
F0000166molecular_functionnucleotide binding
F0003723molecular_functionRNA binding
F0004550molecular_functionnucleoside diphosphate kinase activity
F0005524molecular_functionATP binding
F0016787molecular_functionhydrolase activity
F0016817molecular_functionhydrolase activity, acting on acid anhydrides
F0017111molecular_functionribonucleoside triphosphate phosphatase activity
F0019079biological_processviral genome replication
F0030430cellular_componenthost cell cytoplasm
F0046872molecular_functionmetal ion binding
G0000166molecular_functionnucleotide binding
G0003723molecular_functionRNA binding
G0004550molecular_functionnucleoside diphosphate kinase activity
G0005524molecular_functionATP binding
G0016787molecular_functionhydrolase activity
G0016817molecular_functionhydrolase activity, acting on acid anhydrides
G0017111molecular_functionribonucleoside triphosphate phosphatase activity
G0019079biological_processviral genome replication
G0030430cellular_componenthost cell cytoplasm
G0046872molecular_functionmetal ion binding
U0000166molecular_functionnucleotide binding
U0003723molecular_functionRNA binding
U0004550molecular_functionnucleoside diphosphate kinase activity
U0005524molecular_functionATP binding
U0016787molecular_functionhydrolase activity
U0016817molecular_functionhydrolase activity, acting on acid anhydrides
U0017111molecular_functionribonucleoside triphosphate phosphatase activity
U0019079biological_processviral genome replication
U0030430cellular_componenthost cell cytoplasm
U0046872molecular_functionmetal ion binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsACT_SITE: For NTPase and RTPase activities => ECO:0000255|HAMAP-Rule:MF_04089
ChainResidueDetails
AHIS225
BHIS225
CHIS225
DHIS225
EHIS225
FHIS225
GHIS225
UHIS225

site_idSWS_FT_FI2
Number of Residues32
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04089
ChainResidueDetails
CSER107
CLYS188
CHIS221
CARG227
DSER107
DLYS188
DHIS221
DARG227
ESER107
ELYS188
EHIS221
EARG227
FSER107
FLYS188
FHIS221
FARG227
GSER107
GLYS188
GHIS221
GARG227
USER107
ULYS188
UHIS221
UARG227
ASER107
ALYS188
AHIS221
AARG227
BSER107
BLYS188
BHIS221
BARG227

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PDB entries from 2024-06-12

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