7OG1

AP2 clathrin adaptor core in complex with cargo peptide and FCHO2

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0005794	cellular_component	Golgi apparatus
AAA	0006886	biological_process	intracellular protein transport
AAA	0016192	biological_process	vesicle-mediated transport
AAA	0030117	cellular_component	membrane coat
AAA	0030121	cellular_component	AP-1 adaptor complex
BBB	0006886	biological_process	intracellular protein transport
BBB	0015031	biological_process	protein transport
BBB	0016192	biological_process	vesicle-mediated transport
BBB	0030117	cellular_component	membrane coat
BBB	0030276	molecular_function	clathrin binding
CCC	0006886	biological_process	intracellular protein transport
CCC	0016192	biological_process	vesicle-mediated transport
CCC	0030131	cellular_component	clathrin adaptor complex
MMM	0006886	biological_process	intracellular protein transport
MMM	0016192	biological_process	vesicle-mediated transport
MMM	0030131	cellular_component	clathrin adaptor complex
SSS	0005515	molecular_function	protein binding
SSS	0005737	cellular_component	cytoplasm
SSS	0005886	cellular_component	plasma membrane
SSS	0005905	cellular_component	clathrin-coated pit
SSS	0006886	biological_process	intracellular protein transport
SSS	0006897	biological_process	endocytosis
SSS	0009898	cellular_component	cytoplasmic side of plasma membrane
SSS	0015031	biological_process	protein transport
SSS	0016192	biological_process	vesicle-mediated transport
SSS	0030117	cellular_component	membrane coat
SSS	0030122	cellular_component	AP-2 adaptor complex
SSS	0035615	molecular_function	clathrin adaptor activity
SSS	0043231	cellular_component	intracellular membrane-bounded organelle
SSS	0045202	cellular_component	synapse
SSS	0048488	biological_process	synaptic vesicle endocytosis
SSS	0071944	cellular_component	cell periphery
SSS	0072583	biological_process	clathrin-dependent endocytosis
SSS	0098794	cellular_component	postsynapse
SSS	0098884	biological_process	postsynaptic neurotransmitter receptor internalization
SSS	0098894	cellular_component	extrinsic component of presynaptic endocytic zone membrane
SSS	0098978	cellular_component	glutamatergic synapse

Functional Information from PROSITE/UniProt

site_id	PS00989
Number of Residues	11
Details	CLAT_ADAPTOR_S Clathrin adaptor complexes small chain signature. IIYRryagLYF

Chain	Residue	Details
SSS	ILE57-PHE67

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site_id	PS00990
Number of Residues	21
Details	CLAT_ADAPTOR_M_1 Clathrin adaptor complexes medium chain signature 1. IGWRre.GikYrrNeLFLDVLE

Chain	Residue	Details
MMM	ILE159-GLU179

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site_id	PS00991
Number of Residues	15
Details	CLAT_ADAPTOR_M_2 Clathrin adaptor complexes medium chain signature 2. IsFIPPdGeFeLmrY

Chain	Residue	Details
MMM	ILE274-TYR288

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
GGG	THR385
DDD	THR385
MMM	LYS365
CCC	LYS352
CCC	LYS356
CCC	LYS365

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
GGG	SER387
DDD	SER387

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
GGG	SER394
DDD	SER394

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
GGG	SER403
DDD	SER403

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