7LA1

Crystal structure of phosphoglycerate kinase from Mycobacterium avium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004618	molecular_function	phosphoglycerate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006094	biological_process	gluconeogenesis
A	0006096	biological_process	glycolytic process
A	0016301	molecular_function	kinase activity
A	0043531	molecular_function	ADP binding
B	0004618	molecular_function	phosphoglycerate kinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006094	biological_process	gluconeogenesis
B	0006096	biological_process	glycolytic process
B	0016301	molecular_function	kinase activity
B	0043531	molecular_function	ADP binding
C	0004618	molecular_function	phosphoglycerate kinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006094	biological_process	gluconeogenesis
C	0006096	biological_process	glycolytic process
C	0016301	molecular_function	kinase activity
C	0043531	molecular_function	ADP binding
D	0004618	molecular_function	phosphoglycerate kinase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006094	biological_process	gluconeogenesis
D	0006096	biological_process	glycolytic process
D	0016301	molecular_function	kinase activity
D	0043531	molecular_function	ADP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue EDO A 501

Chain	Residue
A	LYS133
A	ASP134
A	ASP135
A	HOH625
A	HOH631
A	HOH633
A	HOH651
A	HOH701

---

site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 502

Chain	Residue
A	SER210
A	GLY233
A	GLY234
A	HOH658
A	HOH905
A	GLY209

---

site_id	AC3
Number of Residues	8
Details	binding site for residue EDO A 503

Chain	Residue
A	ARG69
A	PRO70
A	ARG125
A	ASP127
A	ALA128
A	THR131
A	HOH753
A	HOH906

---

site_id	AC4
Number of Residues	6
Details	binding site for residue EDO A 504

Chain	Residue
A	ALA350
A	THR353
A	GLY354
A	SER378
A	GLY379
A	HOH790

---

site_id	AC5
Number of Residues	8
Details	binding site for residue EDO B 501

Chain	Residue
A	ASN26
A	ARG43
B	LEU29
B	ASP30
B	SER31
B	ASP32
B	HOH687
B	HOH795

---

site_id	AC6
Number of Residues	7
Details	binding site for residue EDO B 502

Chain	Residue
B	TRP326
B	ASN327
B	GLY328
B	GLY362
B	ALA367
B	VAL370
B	HOH823

---

site_id	AC7
Number of Residues	6
Details	binding site for residue EDO B 503

Chain	Residue
B	SER319
B	ALA321
B	GLU322
B	LYS355
B	HOH742
B	HOH878

---

site_id	AC8
Number of Residues	9
Details	binding site for residue EDO B 504

Chain	Residue
A	HOH629
B	GLY68
B	ARG69
B	LEU78
B	HOH601
B	HOH658
B	HOH794
B	HOH871
B	HOH888

---

site_id	AC9
Number of Residues	5
Details	binding site for residue EDO B 505

Chain	Residue
A	HOH840
B	LEU148
B	HOH616
B	HOH660
B	HOH764

---

site_id	AD1
Number of Residues	5
Details	binding site for residue EDO C 501

Chain	Residue
C	GLN96
C	ARG109
C	GLY112
C	LEU113
C	HOH790

---

site_id	AD2
Number of Residues	8
Details	binding site for residue EDO C 502

Chain	Residue
B	ARG261
B	ARG262
B	ASP265
C	PRO74
C	ASP100
C	VAL101
C	HOH733
C	HOH889

---

site_id	AD3
Number of Residues	5
Details	binding site for residue EDO C 503

Chain	Residue
C	LYS166
C	TYR171
C	PRO400
C	GLU403
C	HOH837

---

site_id	AD4
Number of Residues	4
Details	binding site for residue EDO C 504

Chain	Residue
C	ALA296
C	PRO298
C	HOH672
C	HOH764

---

site_id	AD5
Number of Residues	4
Details	binding site for residue EDO C 505

Chain	Residue
C	LEU176
C	PRO410
C	THR411
C	HOH858

---

site_id	AD6
Number of Residues	5
Details	binding site for residue EDO C 506

Chain	Residue
C	GLY18
C	ALA110
C	LEU148
C	VAL149
C	HOH779

---

site_id	AD7
Number of Residues	8
Details	binding site for residue EDO D 501

Chain	Residue
D	VAL332
D	HOH712
D	HOH750
D	GLY209
D	SER210
D	GLY233
D	GLY234
D	GLY331

---

Functional Information from PROSITE/UniProt

site_id	PS00111
Number of Residues	11
Details	PGLYCERATE_KINASE Phosphoglycerate kinase signature. GVLVRsDlNVP

Chain	Residue	Details
A	GLY18-PRO28

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00145

Chain	Residue	Details
A	ASP24
B	ASP24
B	ARG43
B	HIS66
B	ARG125
B	ARG165
B	LYS215
B	GLY303
B	GLU334
B	GLY363
C	ASP24
A	ARG43
C	ARG43
C	HIS66
C	ARG125
C	ARG165
C	LYS215
C	GLY303
C	GLU334
C	GLY363
D	ASP24
D	ARG43
A	HIS66
D	HIS66
D	ARG125
D	ARG165
D	LYS215
D	GLY303
D	GLU334
D	GLY363
A	ARG125
A	ARG165
A	LYS215
A	GLY303
A	GLU334
A	GLY363

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