7L1F
SARS-CoV-2 RdRp in complex with 4 Remdesivir monophosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0039694 | biological_process | viral RNA genome replication |
| C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| C | 0008242 | molecular_function | omega peptidase activity |
| C | 0016740 | molecular_function | transferase activity |
| D | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| D | 0008242 | molecular_function | omega peptidase activity |
| D | 0016740 | molecular_function | transferase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00213 |
| Number of Residues | 12 |
| Details | LIPOCALIN Lipocalin signature. GTS..KFYGGWHNM |
| Chain | Residue | Details |
| A | GLY590-MET601 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01293 |
| Chain | Residue | Details |
| A | SER759 | |
| A | ASP760 | |
| A | ASP761 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33232691, ECO:0007744|PDB:7CYQ |
| Chain | Residue | Details |
| A | ASN209 | |
| A | ASP218 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01344, ECO:0000269|PubMed:32358203, ECO:0000269|PubMed:32526208, ECO:0000269|PubMed:33232691, ECO:0007744|PDB:7CYQ |
| Chain | Residue | Details |
| A | HIS295 | |
| A | CYS301 | |
| A | CYS306 | |
| A | CYS310 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01293, ECO:0000269|PubMed:32358203, ECO:0000269|PubMed:32526208, ECO:0000269|PubMed:33232691, ECO:0007744|PDB:7CYQ |
| Chain | Residue | Details |
| A | CYS487 | |
| A | HIS642 | |
| A | CYS646 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01293, ECO:0000269|PubMed:32358203, ECO:0000269|PubMed:32526208, ECO:0000269|PubMed:33232691 |
| Chain | Residue | Details |
| A | CYS645 |
