7L0G
Monobody 12VC1 Bound to HRAS(G12C)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0007165 | biological_process | signal transduction |
| A | 0016020 | cellular_component | membrane |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0007165 | biological_process | signal transduction |
| B | 0016020 | cellular_component | membrane |
| E | 0003924 | molecular_function | GTPase activity |
| E | 0005525 | molecular_function | GTP binding |
| E | 0007165 | biological_process | signal transduction |
| E | 0016020 | cellular_component | membrane |
| G | 0003924 | molecular_function | GTPase activity |
| G | 0005525 | molecular_function | GTP binding |
| G | 0007165 | biological_process | signal transduction |
| G | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16698776 |
| Chain | Residue | Details |
| A | GLY13 | |
| B | SER145 | |
| E | GLY13 | |
| E | VAL29 | |
| E | ALA59 | |
| E | ASN116 | |
| E | SER145 | |
| G | GLY13 | |
| G | VAL29 | |
| G | ALA59 | |
| G | ASN116 | |
| A | VAL29 | |
| G | SER145 | |
| A | ALA59 | |
| A | ASN116 | |
| A | SER145 | |
| B | GLY13 | |
| B | VAL29 | |
| B | ALA59 | |
| B | ASN116 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N-acetylmethionine; in GTPase HRas; alternate => ECO:0000269|Ref.12 |
| Chain | Residue | Details |
| A | MET1 | |
| B | MET1 | |
| E | MET1 | |
| G | MET1 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: N-acetylthreonine; in GTPase HRas, N-terminally processed => ECO:0000269|Ref.12 |
| Chain | Residue | Details |
| A | THR2 | |
| B | THR2 | |
| E | THR2 | |
| G | THR2 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: S-nitrosocysteine => ECO:0000269|PubMed:9020151 |
| Chain | Residue | Details |
| A | CYS118 | |
| B | CYS118 | |
| E | CYS118 | |
| G | CYS118 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CARBOHYD: (Microbial infection) O-linked (Glc) threonine; by P.sordellii toxin TcsL => ECO:0000269|PubMed:19744486, ECO:0000269|PubMed:8626575, ECO:0000269|PubMed:8626586, ECO:0000269|PubMed:9632667 |
| Chain | Residue | Details |
| A | THR35 | |
| B | THR35 | |
| E | THR35 | |
| G | THR35 |
