7KWS
Cj1441 with NAD+ and UDP-glucose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000271 | biological_process | polysaccharide biosynthetic process |
| A | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| A | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0045227 | biological_process | capsule polysaccharide biosynthetic process |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000271 | biological_process | polysaccharide biosynthetic process |
| B | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| B | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0045227 | biological_process | capsule polysaccharide biosynthetic process |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | binding site for residue UPG A 401 |
| Chain | Residue |
| A | GLU143 |
| A | ASN245 |
| A | ASN246 |
| A | SER248 |
| A | TYR251 |
| A | GLY252 |
| A | CYS255 |
| A | MET308 |
| A | ARG371 |
| A | NAD402 |
| A | HOH522 |
| A | PHE144 |
| A | HOH528 |
| A | HOH535 |
| A | HOH538 |
| A | HOH539 |
| B | ARG239 |
| A | LEU145 |
| A | ARG146 |
| A | GLU147 |
| A | LYS199 |
| A | ASN203 |
| A | VAL210 |
| A | TYR244 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | binding site for residue NAD A 402 |
| Chain | Residue |
| A | VAL6 |
| A | GLY7 |
| A | GLY9 |
| A | TYR10 |
| A | VAL11 |
| A | ASP31 |
| A | ILE32 |
| A | LYS36 |
| A | ALA82 |
| A | THR83 |
| A | PRO84 |
| A | THR85 |
| A | THR120 |
| A | GLU143 |
| A | LEU145 |
| A | GLU147 |
| A | TYR254 |
| A | CYS255 |
| A | LYS258 |
| A | ARG316 |
| A | UPG401 |
| A | HOH513 |
| A | HOH514 |
| A | HOH515 |
| A | HOH533 |
| A | HOH554 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | binding site for residue UPG B 401 |
| Chain | Residue |
| A | ARG239 |
| B | GLU143 |
| B | PHE144 |
| B | LEU145 |
| B | ARG146 |
| B | GLU147 |
| B | LYS199 |
| B | ASN203 |
| B | VAL210 |
| B | TYR244 |
| B | ASN245 |
| B | ASN246 |
| B | SER248 |
| B | TYR251 |
| B | GLY252 |
| B | CYS255 |
| B | LEU256 |
| B | MET308 |
| B | LYS309 |
| B | ARG371 |
| B | NAD402 |
| B | HOH518 |
| B | HOH529 |
| B | HOH545 |
| B | HOH565 |
| site_id | AC4 |
| Number of Residues | 26 |
| Details | binding site for residue NAD B 402 |
| Chain | Residue |
| B | HOH553 |
| B | HOH557 |
| B | VAL6 |
| B | GLY7 |
| B | GLY9 |
| B | TYR10 |
| B | VAL11 |
| B | ASP31 |
| B | ILE32 |
| B | ASP33 |
| B | LYS36 |
| B | ALA82 |
| B | THR83 |
| B | PRO84 |
| B | THR85 |
| B | THR120 |
| B | GLU143 |
| B | LEU145 |
| B | GLU147 |
| B | TYR254 |
| B | CYS255 |
| B | ARG316 |
| B | UPG401 |
| B | HOH513 |
| B | HOH531 |
| B | HOH538 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|PIRSR:PIRSR500134-1, ECO:0000305|PubMed:33621065 |
| Chain | Residue | Details |
| A | CYS255 | |
| B | CYS255 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33621065, ECO:0007744|PDB:7KWS |
| Chain | Residue | Details |
| A | VAL11 | |
| A | LYS199 | |
| A | ASN203 | |
| A | TYR244 | |
| A | GLY252 | |
| A | TYR254 | |
| A | LYS309 | |
| B | VAL11 | |
| B | GLU143 | |
| B | LYS199 | |
| B | ASN203 | |
| B | TYR244 | |
| B | GLY252 | |
| B | TYR254 | |
| B | LYS309 | |
| A | GLU143 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | BINDING: BINDING => ECO:0000255|PIRSR:PIRSR500134-3, ECO:0000269|PubMed:33621065, ECO:0007744|PDB:7KWS |
| Chain | Residue | Details |
| A | ASP31 | |
| A | LYS36 | |
| A | THR85 | |
| B | LYS258 | |
| B | ARG316 | |
| A | THR120 | |
| A | GLU147 | |
| A | LYS258 | |
| A | ARG316 | |
| B | ASP31 | |
| B | LYS36 | |
| B | THR85 | |
| B | THR120 | |
| B | GLU147 |
