Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7JTH

Cryo-EM structure of unliganded octameric prenyltransferase domain of Phomopsis amygdali fusicoccadiene synthase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004311	molecular_function	farnesyltranstransferase activity
A	0004659	molecular_function	prenyltransferase activity
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016829	molecular_function	lyase activity
A	0042181	biological_process	ketone biosynthetic process
A	0043386	biological_process	mycotoxin biosynthetic process
A	0046165	biological_process	alcohol biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0004311	molecular_function	farnesyltranstransferase activity
B	0004659	molecular_function	prenyltransferase activity
B	0008299	biological_process	isoprenoid biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016829	molecular_function	lyase activity
B	0042181	biological_process	ketone biosynthetic process
B	0043386	biological_process	mycotoxin biosynthetic process
B	0046165	biological_process	alcohol biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0004311	molecular_function	farnesyltranstransferase activity
C	0004659	molecular_function	prenyltransferase activity
C	0008299	biological_process	isoprenoid biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016829	molecular_function	lyase activity
C	0042181	biological_process	ketone biosynthetic process
C	0043386	biological_process	mycotoxin biosynthetic process
C	0046165	biological_process	alcohol biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0004311	molecular_function	farnesyltranstransferase activity
D	0004659	molecular_function	prenyltransferase activity
D	0008299	biological_process	isoprenoid biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016829	molecular_function	lyase activity
D	0042181	biological_process	ketone biosynthetic process
D	0043386	biological_process	mycotoxin biosynthetic process
D	0046165	biological_process	alcohol biosynthetic process
D	0046872	molecular_function	metal ion binding
E	0004311	molecular_function	farnesyltranstransferase activity
E	0004659	molecular_function	prenyltransferase activity
E	0008299	biological_process	isoprenoid biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016829	molecular_function	lyase activity
E	0042181	biological_process	ketone biosynthetic process
E	0043386	biological_process	mycotoxin biosynthetic process
E	0046165	biological_process	alcohol biosynthetic process
E	0046872	molecular_function	metal ion binding
F	0004311	molecular_function	farnesyltranstransferase activity
F	0004659	molecular_function	prenyltransferase activity
F	0008299	biological_process	isoprenoid biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016829	molecular_function	lyase activity
F	0042181	biological_process	ketone biosynthetic process
F	0043386	biological_process	mycotoxin biosynthetic process
F	0046165	biological_process	alcohol biosynthetic process
F	0046872	molecular_function	metal ion binding
G	0004311	molecular_function	farnesyltranstransferase activity
G	0004659	molecular_function	prenyltransferase activity
G	0008299	biological_process	isoprenoid biosynthetic process
G	0016740	molecular_function	transferase activity
G	0016829	molecular_function	lyase activity
G	0042181	biological_process	ketone biosynthetic process
G	0043386	biological_process	mycotoxin biosynthetic process
G	0046165	biological_process	alcohol biosynthetic process
G	0046872	molecular_function	metal ion binding
H	0004311	molecular_function	farnesyltranstransferase activity
H	0004659	molecular_function	prenyltransferase activity
H	0008299	biological_process	isoprenoid biosynthetic process
H	0016740	molecular_function	transferase activity
H	0016829	molecular_function	lyase activity
H	0042181	biological_process	ketone biosynthetic process
H	0043386	biological_process	mycotoxin biosynthetic process
H	0046165	biological_process	alcohol biosynthetic process
H	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00444
Number of Residues	13
Details	POLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. LGrcFQIrDDYqN

Chain	Residue	Details
A	LEU597-ASN609

site_id	PS00723
Number of Residues	15
Details	POLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LLlDDfq..DnsplRRG

Chain	Residue	Details
A	LEU471-GLY485

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	BINDING: BINDING => ECO:0000269\|PubMed:26734760, ECO:0007744\|PDB:5ER8

Chain	Residue	Details
C	SER236
C	ARG325
D	ASP92
D	ASP96
D	ARG188
D	ASN232
D	SER236
D	ARG325
E	ASP92
E	ASP96
E	ARG188
E	ASN232
E	SER236
E	ARG325
F	ASP92
F	ASP96
F	ARG188
F	ASN232
F	SER236
F	ARG325
G	ASP92
G	ASP96
G	ARG188
G	ASN232
G	SER236
G	ARG325
H	ASP92
H	ASP96
H	ARG188
H	ASN232
H	SER236
H	ARG325
A	ARG188
A	ASN232
A	SER236
A	ARG325
B	ASP92
B	ASP96
B	ARG188
B	ASN232
B	SER236
B	ARG325
C	ASP92
C	ASP96
C	ARG188
C	ASN232
A	ASP92
A	ASP96

site_id	SWS_FT_FI2
Number of Residues	104
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:Q12051

Chain	Residue	Details
B	ASP474
B	ASP478
B	ARG483
B	ARG484
B	LYS561
B	THR562
B	GLN602
B	ASN609
B	LYS619
B	LYS629
C	LYS435
C	ARG438
C	HIS467
C	ASP474
C	ASP478
C	ARG483
C	ARG484
C	LYS561
C	THR562
C	GLN602
C	ASN609
C	LYS619
C	LYS629
D	LYS435
D	ARG438
D	HIS467
D	ASP474
D	ASP478
D	ARG483
D	ARG484
D	LYS561
D	THR562
D	GLN602
D	ASN609
D	LYS619
D	LYS629
E	LYS435
E	ARG438
E	HIS467
E	ASP474
E	ASP478
E	ARG483
E	ARG484
E	LYS561
E	THR562
E	GLN602
E	ASN609
E	LYS619
E	LYS629
F	LYS435
F	ARG438
F	HIS467
F	ASP474
F	ASP478
F	ARG483
F	ARG484
F	LYS561
F	THR562
F	GLN602
F	ASN609
F	LYS619
F	LYS629
G	LYS435
G	ARG438
G	HIS467
G	ASP474
G	ASP478
G	ARG483
G	ARG484
G	LYS561
G	THR562
G	GLN602
G	ASN609
G	LYS619
G	LYS629
H	LYS435
H	ARG438
H	HIS467
H	ASP474
H	ASP478
H	ARG483
H	ARG484
H	LYS561
H	THR562
H	GLN602
H	ASN609
H	LYS619
H	LYS629
A	HIS467
A	ASP474
A	ASP478
A	ARG483
A	ARG484
A	LYS561
A	THR562
A	GLN602
A	ASN609
A	LYS619
A	LYS629
B	LYS435
B	ARG438
B	HIS467
A	LYS435
A	ARG438

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)