Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7JR1

Crystal structure of the R64F mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Bovine Trypsin

Functional Information from GO Data
ChainGOidnamespacecontents
A0004175molecular_functionendopeptidase activity
A0004252molecular_functionserine-type endopeptidase activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006508biological_processproteolysis
A0007586biological_processdigestion
A0008236molecular_functionserine-type peptidase activity
A0046872molecular_functionmetal ion binding
A0097180cellular_componentserine protease inhibitor complex
A0097655molecular_functionserpin family protein binding
B0004175molecular_functionendopeptidase activity
B0004252molecular_functionserine-type endopeptidase activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0006508biological_processproteolysis
B0007586biological_processdigestion
B0008236molecular_functionserine-type peptidase activity
B0046872molecular_functionmetal ion binding
B0097180cellular_componentserine protease inhibitor complex
B0097655molecular_functionserpin family protein binding
C0004175molecular_functionendopeptidase activity
C0004252molecular_functionserine-type endopeptidase activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0006508biological_processproteolysis
C0007586biological_processdigestion
C0008236molecular_functionserine-type peptidase activity
C0046872molecular_functionmetal ion binding
C0097180cellular_componentserine protease inhibitor complex
C0097655molecular_functionserpin family protein binding
D0004175molecular_functionendopeptidase activity
D0004252molecular_functionserine-type endopeptidase activity
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0006508biological_processproteolysis
D0007586biological_processdigestion
D0008236molecular_functionserine-type peptidase activity
D0046872molecular_functionmetal ion binding
D0097180cellular_componentserine protease inhibitor complex
D0097655molecular_functionserpin family protein binding
E0004175molecular_functionendopeptidase activity
E0004252molecular_functionserine-type endopeptidase activity
E0005515molecular_functionprotein binding
E0005576cellular_componentextracellular region
E0005615cellular_componentextracellular space
E0006508biological_processproteolysis
E0007586biological_processdigestion
E0008236molecular_functionserine-type peptidase activity
E0046872molecular_functionmetal ion binding
E0097180cellular_componentserine protease inhibitor complex
E0097655molecular_functionserpin family protein binding
F0004175molecular_functionendopeptidase activity
F0004252molecular_functionserine-type endopeptidase activity
F0005515molecular_functionprotein binding
F0005576cellular_componentextracellular region
F0005615cellular_componentextracellular space
F0006508biological_processproteolysis
F0007586biological_processdigestion
F0008236molecular_functionserine-type peptidase activity
F0046872molecular_functionmetal ion binding
F0097180cellular_componentserine protease inhibitor complex
F0097655molecular_functionserpin family protein binding
G0004866molecular_functionendopeptidase inhibitor activity
G0004867molecular_functionserine-type endopeptidase inhibitor activity
G0005576cellular_componentextracellular region
H0004866molecular_functionendopeptidase inhibitor activity
H0004867molecular_functionserine-type endopeptidase inhibitor activity
H0005576cellular_componentextracellular region
I0004866molecular_functionendopeptidase inhibitor activity
I0004867molecular_functionserine-type endopeptidase inhibitor activity
I0005576cellular_componentextracellular region
J0004866molecular_functionendopeptidase inhibitor activity
J0004867molecular_functionserine-type endopeptidase inhibitor activity
J0005576cellular_componentextracellular region
K0004866molecular_functionendopeptidase inhibitor activity
K0004867molecular_functionserine-type endopeptidase inhibitor activity
K0005576cellular_componentextracellular region
L0004866molecular_functionendopeptidase inhibitor activity
L0004867molecular_functionserine-type endopeptidase inhibitor activity
L0005576cellular_componentextracellular region
Functional Information from PROSITE/UniProt
site_idPS00134
Number of Residues6
DetailsTRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC
ChainResidueDetails
AVAL53-CYS58

site_idPS00135
Number of Residues12
DetailsTRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV
ChainResidueDetails
AASP189-VAL200

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues18
DetailsACT_SITE: Charge relay system
ChainResidueDetails
AHIS57
DHIS57
DASP102
DSER195
EHIS57
EASP102
ESER195
FHIS57
FASP102
FSER195
AASP102
ASER195
BHIS57
BASP102
BSER195
CHIS57
CASP102
CSER195

site_idSWS_FT_FI2
Number of Residues42
DetailsBINDING:
ChainResidueDetails
AGLU70
BVAL75
BGLU80
BASP189
BGLN192
BSER195
CGLU70
CASN72
CVAL75
CGLU80
CASP189
AASN72
CGLN192
CSER195
DGLU70
DASN72
DVAL75
DGLU80
DASP189
DGLN192
DSER195
EGLU70
AVAL75
EASN72
EVAL75
EGLU80
EASP189
EGLN192
ESER195
FGLU70
FASN72
FVAL75
FGLU80
AGLU80
FASP189
FGLN192
FSER195
AASP189
AGLN192
ASER195
BGLU70
BASN72

220113

PDB entries from 2024-05-22

PDB statisticsPDBj update infoContact PDBjnumon