7JH4
Crystal structure of NAD(P)H-flavin oxidoreductase (NfoR) from S. aureus complexed with reduced FMN and NAD+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| A | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| B | 0005829 | cellular_component | cytosol |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| B | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| C | 0005829 | cellular_component | cytosol |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| C | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| D | 0005829 | cellular_component | cytosol |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| D | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| E | 0005829 | cellular_component | cytosol |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| E | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | binding site for residue FNR A 301 |
| Chain | Residue |
| A | ARG15 |
| A | GLU166 |
| A | GLY167 |
| A | LYS207 |
| A | ARG209 |
| A | HOH452 |
| A | HOH464 |
| A | HOH471 |
| A | HOH476 |
| A | HOH496 |
| B | PRO43 |
| A | HIS16 |
| B | SER44 |
| B | SER45 |
| B | GLY47 |
| B | GLN143 |
| B | ILE146 |
| B | NAD302 |
| B | HOH441 |
| A | ALA17 |
| A | LYS19 |
| A | GLY71 |
| A | GLN75 |
| A | TYR145 |
| A | PRO164 |
| A | MET165 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | binding site for residue FNR B 301 |
| Chain | Residue |
| A | PRO43 |
| A | SER44 |
| A | SER45 |
| A | GLY47 |
| A | GLN143 |
| A | ILE146 |
| B | ARG15 |
| B | HIS16 |
| B | ALA17 |
| B | LYS19 |
| B | GLY71 |
| B | GLN75 |
| B | TYR145 |
| B | PRO164 |
| B | MET165 |
| B | GLU166 |
| B | GLY167 |
| B | LYS207 |
| B | ARG209 |
| B | HOH433 |
| B | HOH453 |
| B | HOH500 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue NAD B 302 |
| Chain | Residue |
| A | GLY167 |
| A | FNR301 |
| A | HOH496 |
| B | LEU46 |
| B | PHE123 |
| B | HOH502 |
| B | HOH541 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | binding site for residue FNR C 301 |
| Chain | Residue |
| C | ARG15 |
| C | HIS16 |
| C | ALA17 |
| C | LYS19 |
| C | PRO43 |
| C | SER44 |
| C | SER45 |
| C | GLY47 |
| C | GLY71 |
| C | GLN75 |
| C | GLN143 |
| C | TYR145 |
| C | ILE146 |
| C | PRO164 |
| C | MET165 |
| C | GLU166 |
| C | GLY167 |
| C | LYS207 |
| C | ARG209 |
| C | NAD302 |
| C | HOH428 |
| C | HOH464 |
| C | HOH500 |
| C | HOH514 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue NAD C 302 |
| Chain | Residue |
| C | LEU46 |
| C | PHE123 |
| C | GLY167 |
| C | FNR301 |
| C | HOH413 |
| C | HOH431 |
| C | HOH478 |
| site_id | AC6 |
| Number of Residues | 24 |
| Details | binding site for residue FNR D 301 |
| Chain | Residue |
| D | HOH424 |
| D | HOH428 |
| D | HOH449 |
| D | HOH452 |
| D | HOH455 |
| E | PRO43 |
| E | SER44 |
| E | SER45 |
| E | GLY47 |
| E | GLN143 |
| E | ILE146 |
| D | ARG15 |
| D | HIS16 |
| D | ALA17 |
| D | LYS19 |
| D | GLY71 |
| D | GLN75 |
| D | TYR145 |
| D | PRO164 |
| D | MET165 |
| D | GLU166 |
| D | GLY167 |
| D | LYS207 |
| D | ARG209 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | binding site for residue FNR E 301 |
| Chain | Residue |
| D | PRO43 |
| D | SER44 |
| D | SER45 |
| D | LEU46 |
| D | GLY47 |
| D | GLN143 |
| D | ILE146 |
| E | ARG15 |
| E | ALA17 |
| E | LYS19 |
| E | GLY71 |
| E | GLN75 |
| E | TYR145 |
| E | PRO164 |
| E | MET165 |
| E | GLU166 |
| E | GLY167 |
| E | LYS207 |
| E | ARG209 |
| E | HOH437 |
