7JGB

Cryo-EM structure of bedaquiline-free Mycobacterium smegmatis ATP synthase FO region

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0005886	cellular_component	plasma membrane
1	0006754	biological_process	ATP biosynthetic process
1	0008289	molecular_function	lipid binding
1	0015078	molecular_function	proton transmembrane transporter activity
1	0015986	biological_process	proton motive force-driven ATP synthesis
1	0016787	molecular_function	hydrolase activity
1	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
1	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
1	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
1	1902600	biological_process	proton transmembrane transport
2	0005886	cellular_component	plasma membrane
2	0006754	biological_process	ATP biosynthetic process
2	0008289	molecular_function	lipid binding
2	0015078	molecular_function	proton transmembrane transporter activity
2	0015986	biological_process	proton motive force-driven ATP synthesis
2	0016787	molecular_function	hydrolase activity
2	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
2	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
2	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
2	1902600	biological_process	proton transmembrane transport
3	0005886	cellular_component	plasma membrane
3	0006754	biological_process	ATP biosynthetic process
3	0008289	molecular_function	lipid binding
3	0015078	molecular_function	proton transmembrane transporter activity
3	0015986	biological_process	proton motive force-driven ATP synthesis
3	0016787	molecular_function	hydrolase activity
3	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
3	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
3	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
3	1902600	biological_process	proton transmembrane transport
4	0005886	cellular_component	plasma membrane
4	0006754	biological_process	ATP biosynthetic process
4	0008289	molecular_function	lipid binding
4	0015078	molecular_function	proton transmembrane transporter activity
4	0015986	biological_process	proton motive force-driven ATP synthesis
4	0016787	molecular_function	hydrolase activity
4	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
4	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
4	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
4	1902600	biological_process	proton transmembrane transport
5	0005886	cellular_component	plasma membrane
5	0006754	biological_process	ATP biosynthetic process
5	0008289	molecular_function	lipid binding
5	0015078	molecular_function	proton transmembrane transporter activity
5	0015986	biological_process	proton motive force-driven ATP synthesis
5	0016787	molecular_function	hydrolase activity
5	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
5	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
5	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
5	1902600	biological_process	proton transmembrane transport
6	0005886	cellular_component	plasma membrane
6	0006754	biological_process	ATP biosynthetic process
6	0008289	molecular_function	lipid binding
6	0015078	molecular_function	proton transmembrane transporter activity
6	0015986	biological_process	proton motive force-driven ATP synthesis
6	0016787	molecular_function	hydrolase activity
6	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
6	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
6	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
6	1902600	biological_process	proton transmembrane transport
7	0005886	cellular_component	plasma membrane
7	0006754	biological_process	ATP biosynthetic process
7	0008289	molecular_function	lipid binding
7	0015078	molecular_function	proton transmembrane transporter activity
7	0015986	biological_process	proton motive force-driven ATP synthesis
7	0016787	molecular_function	hydrolase activity
7	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
7	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
7	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
7	1902600	biological_process	proton transmembrane transport
8	0005886	cellular_component	plasma membrane
8	0006754	biological_process	ATP biosynthetic process
8	0008289	molecular_function	lipid binding
8	0015078	molecular_function	proton transmembrane transporter activity
8	0015986	biological_process	proton motive force-driven ATP synthesis
8	0016787	molecular_function	hydrolase activity
8	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
8	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
8	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
8	1902600	biological_process	proton transmembrane transport
9	0005886	cellular_component	plasma membrane
9	0006754	biological_process	ATP biosynthetic process
9	0008289	molecular_function	lipid binding
9	0015078	molecular_function	proton transmembrane transporter activity
9	0015986	biological_process	proton motive force-driven ATP synthesis
9	0016787	molecular_function	hydrolase activity
9	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
9	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
9	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
9	1902600	biological_process	proton transmembrane transport
a	0005886	cellular_component	plasma membrane
a	0006754	biological_process	ATP biosynthetic process
a	0015078	molecular_function	proton transmembrane transporter activity
a	0015986	biological_process	proton motive force-driven ATP synthesis
a	0016787	molecular_function	hydrolase activity
a	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
a	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
a	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
a	1902600	biological_process	proton transmembrane transport
b	0005886	cellular_component	plasma membrane
b	0006754	biological_process	ATP biosynthetic process
b	0015078	molecular_function	proton transmembrane transporter activity
b	0015986	biological_process	proton motive force-driven ATP synthesis
b	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
b	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
b	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
b	1902600	biological_process	proton transmembrane transport
d	0003824	molecular_function	catalytic activity
d	0005886	cellular_component	plasma membrane
d	0006754	biological_process	ATP biosynthetic process
d	0009772	biological_process	photosynthetic electron transport in photosystem II
d	0009773	biological_process	photosynthetic electron transport in photosystem I
d	0015078	molecular_function	proton transmembrane transporter activity
d	0015986	biological_process	proton motive force-driven ATP synthesis
d	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
d	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
d	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
d	1902600	biological_process	proton transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00605
Number of Residues	22
Details	ATPASE_C ATP synthase c subunit signature. ARQPeaqgrLfTpfFItvgLvE

Chain	Residue	Details
1	ALA44-GLU65

---

site_id	PS00449
Number of Residues	10
Details	ATPASE_A ATP synthase a subunit signature. SLALRLFGNI

Chain	Residue	Details
a	SER184-ILE193

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_01398

Chain	Residue	Details
b	LEU25-ILE45

---