7F51
Crystal structure of Hst2 in complex with 2'-O-Benzoyl ADP Ribose
Functional Information from GO Data
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00236, ECO:0000269|PubMed:20726530 |
Chain | Residue | Details |
A | HIS135 |
site_id | SWS_FT_FI2 |
Number of Residues | 5 |
Details | BINDING: BINDING => ECO:0000269|PubMed:14502267, ECO:0000269|PubMed:15150415 |
Chain | Residue | Details |
A | GLN115 | |
A | GLY223 | |
A | ASN248 | |
A | SER270 | |
A | GLY32 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00236, ECO:0000269|PubMed:14502267, ECO:0000269|PubMed:14604530, ECO:0000269|PubMed:15150415, ECO:0000269|PubMed:17289592 |
Chain | Residue | Details |
A | CYS143 | |
A | CYS146 | |
A | CYS170 | |
A | CYS173 |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 7 |
Details | M-CSA 240 |
Chain | Residue | Details |
A | PRO42 | hydrogen bond acceptor, steric role |
A | ASP43 | hydrogen bond acceptor, hydrogen bond donor, steric role |
A | PHE44 | steric role, van der waals interaction |
A | ARG45 | electrostatic stabiliser, hydrogen bond donor |
A | ASN116 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, increase nucleophilicity |
A | ASP118 | activator, hydrogen bond acceptor |
A | HIS135 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |