7E2Q

Crystal structure of Mycoplasma pneumoniae Enolase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000015	cellular_component	phosphopyruvate hydratase complex
A	0000287	molecular_function	magnesium ion binding
A	0004634	molecular_function	phosphopyruvate hydratase activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006096	biological_process	glycolytic process
A	0009986	cellular_component	cell surface
A	0016829	molecular_function	lyase activity
A	0046872	molecular_function	metal ion binding
B	0000015	cellular_component	phosphopyruvate hydratase complex
B	0000287	molecular_function	magnesium ion binding
B	0004634	molecular_function	phosphopyruvate hydratase activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006096	biological_process	glycolytic process
B	0009986	cellular_component	cell surface
B	0016829	molecular_function	lyase activity
B	0046872	molecular_function	metal ion binding
C	0000015	cellular_component	phosphopyruvate hydratase complex
C	0000287	molecular_function	magnesium ion binding
C	0004634	molecular_function	phosphopyruvate hydratase activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006096	biological_process	glycolytic process
C	0009986	cellular_component	cell surface
C	0016829	molecular_function	lyase activity
C	0046872	molecular_function	metal ion binding
D	0000015	cellular_component	phosphopyruvate hydratase complex
D	0000287	molecular_function	magnesium ion binding
D	0004634	molecular_function	phosphopyruvate hydratase activity
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006096	biological_process	glycolytic process
D	0009986	cellular_component	cell surface
D	0016829	molecular_function	lyase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 501

Chain	Residue
A	GLY48
A	ALA49
A	LYS362
A	ARG391
A	SER392

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 B 501

Chain	Residue
B	HOH729
B	GLY48
B	LYS362
B	ARG391
B	SER392

---

site_id	AC3
Number of Residues	6
Details	binding site for residue SO4 C 501

Chain	Residue
C	GLY48
C	ALA49
C	LYS362
C	ARG391
C	SER392
C	HOH602

---

site_id	AC4
Number of Residues	5
Details	binding site for residue SO4 D 501

Chain	Residue
D	GLY48
D	ALA49
D	LYS362
D	ARG391
D	SER392

---

Functional Information from PROSITE/UniProt

site_id	PS00164
Number of Residues	14
Details	ENOLASE Enolase signature. ILIKlNQIGTLTET

Chain	Residue	Details
A	ILE359-THR372

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00318

Chain	Residue	Details
A	GLU219
B	GLU219
C	GLU219
D	GLU219

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00318

Chain	Residue	Details
A	LYS362
B	LYS362
C	LYS362
D	LYS362

---

site_id	SWS_FT_FI3
Number of Residues	28
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00318

Chain	Residue	Details
A	HIS169
B	ASP256
B	GLU310
B	ASP337
B	SER389
B	LYS413
C	HIS169
C	GLU178
C	ASP256
C	GLU310
C	ASP337
A	GLU178
C	SER389
C	LYS413
D	HIS169
D	GLU178
D	ASP256
D	GLU310
D	ASP337
D	SER389
D	LYS413
A	ASP256
A	GLU310
A	ASP337
A	SER389
A	LYS413
B	HIS169
B	GLU178

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: covalent; in inhibited form => ECO:0000255|HAMAP-Rule:MF_00318

Chain	Residue	Details
A	LYS362
B	LYS362
C	LYS362
D	LYS362

---