7E13
Caprylic acid targets a serine hydroxymethyltransferase to kill horseweed
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| A | 0019264 | biological_process | glycine biosynthetic process from serine |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0035999 | biological_process | tetrahydrofolate interconversion |
| B | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| B | 0019264 | biological_process | glycine biosynthetic process from serine |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0035999 | biological_process | tetrahydrofolate interconversion |
| C | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| C | 0019264 | biological_process | glycine biosynthetic process from serine |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0035999 | biological_process | tetrahydrofolate interconversion |
| D | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
| D | 0019264 | biological_process | glycine biosynthetic process from serine |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0035999 | biological_process | tetrahydrofolate interconversion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue PLP A 601 |
| Chain | Residue |
| A | SER144 |
| A | THR279 |
| A | HIS281 |
| A | LYS282 |
| B | TYR98 |
| B | GLY326 |
| B | GLY327 |
| A | GLY145 |
| A | SER146 |
| A | HIS173 |
| A | SER175 |
| A | SER228 |
| A | ASP253 |
| A | ALA255 |
| A | HIS256 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue PLP B 601 |
| Chain | Residue |
| A | TYR98 |
| A | GLY326 |
| A | GLY327 |
| B | SER144 |
| B | GLY145 |
| B | SER146 |
| B | HIS173 |
| B | ALA227 |
| B | SER228 |
| B | ASP253 |
| B | ALA255 |
| B | HIS256 |
| B | THR279 |
| B | HIS281 |
| B | LYS282 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue PLP C 601 |
| Chain | Residue |
| C | SER144 |
| C | GLY145 |
| C | SER146 |
| C | HIS173 |
| C | ALA227 |
| C | SER228 |
| C | ASP253 |
| C | ALA255 |
| C | HIS256 |
| C | THR279 |
| C | HIS281 |
| C | LYS282 |
| D | TYR98 |
| D | GLY326 |
| D | GLY327 |
Functional Information from PROSITE/UniProt
| site_id | PS00096 |
| Number of Residues | 17 |
| Details | SHMT Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. DVvTTTTHKSLrGPRGA |
| Chain | Residue | Details |
| A | ASP274-ALA290 |
