Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7DD9

Cryo-EM structure of the Ams1 and Nbr1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000328	cellular_component	fungal-type vacuole lumen
A	0000329	cellular_component	fungal-type vacuole membrane
A	0004559	molecular_function	alpha-mannosidase activity
A	0004571	molecular_function	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005773	cellular_component	vacuole
A	0005829	cellular_component	cytosol
A	0006013	biological_process	mannose metabolic process
A	0006974	biological_process	DNA damage response
A	0008270	molecular_function	zinc ion binding
A	0008643	biological_process	carbohydrate transport
A	0009313	biological_process	oligosaccharide catabolic process
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0034219	biological_process	carbohydrate transmembrane transport
A	0034289	biological_process	detection of maltose stimulus
A	0042597	cellular_component	periplasmic space
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0046872	molecular_function	metal ion binding
A	0052767	molecular_function	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
A	0052768	molecular_function	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0060326	biological_process	cell chemotaxis
A	0071702	biological_process	organic substance transport
A	1901982	molecular_function	maltose binding
A	1990060	cellular_component	maltose transport complex
C	0000328	cellular_component	fungal-type vacuole lumen
C	0000329	cellular_component	fungal-type vacuole membrane
C	0004559	molecular_function	alpha-mannosidase activity
C	0004571	molecular_function	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005773	cellular_component	vacuole
C	0005829	cellular_component	cytosol
C	0006013	biological_process	mannose metabolic process
C	0006974	biological_process	DNA damage response
C	0008270	molecular_function	zinc ion binding
C	0008643	biological_process	carbohydrate transport
C	0009313	biological_process	oligosaccharide catabolic process
C	0015768	biological_process	maltose transport
C	0016020	cellular_component	membrane
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0034219	biological_process	carbohydrate transmembrane transport
C	0034289	biological_process	detection of maltose stimulus
C	0042597	cellular_component	periplasmic space
C	0042956	biological_process	maltodextrin transmembrane transport
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0046872	molecular_function	metal ion binding
C	0052767	molecular_function	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
C	0052768	molecular_function	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0055085	biological_process	transmembrane transport
C	0060326	biological_process	cell chemotaxis
C	0071702	biological_process	organic substance transport
C	1901982	molecular_function	maltose binding
C	1990060	cellular_component	maltose transport complex
E	0000328	cellular_component	fungal-type vacuole lumen
E	0000329	cellular_component	fungal-type vacuole membrane
E	0004559	molecular_function	alpha-mannosidase activity
E	0004571	molecular_function	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005773	cellular_component	vacuole
E	0005829	cellular_component	cytosol
E	0006013	biological_process	mannose metabolic process
E	0006974	biological_process	DNA damage response
E	0008270	molecular_function	zinc ion binding
E	0008643	biological_process	carbohydrate transport
E	0009313	biological_process	oligosaccharide catabolic process
E	0015768	biological_process	maltose transport
E	0016020	cellular_component	membrane
E	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
E	0030288	cellular_component	outer membrane-bounded periplasmic space
E	0034219	biological_process	carbohydrate transmembrane transport
E	0034289	biological_process	detection of maltose stimulus
E	0042597	cellular_component	periplasmic space
E	0042956	biological_process	maltodextrin transmembrane transport
E	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
E	0046872	molecular_function	metal ion binding
E	0052767	molecular_function	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
E	0052768	molecular_function	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
E	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
E	0055085	biological_process	transmembrane transport
E	0060326	biological_process	cell chemotaxis
E	0071702	biological_process	organic substance transport
E	1901982	molecular_function	maltose binding
E	1990060	cellular_component	maltose transport complex
G	0000328	cellular_component	fungal-type vacuole lumen
G	0000329	cellular_component	fungal-type vacuole membrane
G	0004559	molecular_function	alpha-mannosidase activity
G	0004571	molecular_function	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005773	cellular_component	vacuole
G	0005829	cellular_component	cytosol
G	0006013	biological_process	mannose metabolic process
G	0006974	biological_process	DNA damage response
G	0008270	molecular_function	zinc ion binding
G	0008643	biological_process	carbohydrate transport
G	0009313	biological_process	oligosaccharide catabolic process
G	0015768	biological_process	maltose transport
G	0016020	cellular_component	membrane
G	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
G	0030288	cellular_component	outer membrane-bounded periplasmic space
G	0034219	biological_process	carbohydrate transmembrane transport
G	0034289	biological_process	detection of maltose stimulus
G	0042597	cellular_component	periplasmic space
G	0042956	biological_process	maltodextrin transmembrane transport
G	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
G	0046872	molecular_function	metal ion binding
G	0052767	molecular_function	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
G	0052768	molecular_function	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
G	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
G	0055085	biological_process	transmembrane transport
G	0060326	biological_process	cell chemotaxis
G	0071702	biological_process	organic substance transport
G	1901982	molecular_function	maltose binding
G	1990060	cellular_component	maltose transport complex

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO3133-ASN3150

site_id	PS01357
Number of Residues	27
Details	ZF_ZZ_1 Zinc finger ZZ-type signature. CntClkiirnd.SFhCtk...CfDFdVCrdC

Chain	Residue	Details
A	CYS2062-CYS2088
A	CYS2136-CYS2162

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000250

Chain	Residue	Details
C	ASP402
E	ASP402
G	ASP402
A	ASP402

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
C	HIS290
C	ASP292
C	ASP402
C	HIS615
E	HIS290
E	ASP292
E	ASP402
E	HIS615
G	HIS290
G	ASP292
G	ASP402
G	HIS615
A	HIS290
A	ASP292
A	ASP402
A	HIS615

site_id	SWS_FT_FI3
Number of Residues	220
Details	ZN_FING: ZZ-type 1 => ECO:0000255\|PROSITE-ProRule:PRU00228

Chain	Residue	Details
A	SER2057-SER2112
C	SER2057-SER2112
E	SER2057-SER2112
G	SER2057-SER2112

site_id	SWS_FT_FI4
Number of Residues	64
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU00228

Chain	Residue	Details
C	CYS2062
C	CYS2065
C	CYS2076
C	CYS2079
C	CYS2085
C	CYS2088
C	HIS2096
C	HIS2102
C	CYS2136
C	CYS2139
C	CYS2150
C	CYS2153
C	CYS2159
C	CYS2162
C	HIS2168
C	HIS2172
E	CYS2062
E	CYS2065
E	CYS2076
E	CYS2079
E	CYS2085
E	CYS2088
E	HIS2096
E	HIS2102
E	CYS2136
E	CYS2139
E	CYS2150
E	CYS2153
E	CYS2159
E	CYS2162
E	HIS2168
E	HIS2172
G	CYS2062
G	CYS2065
G	CYS2076
G	CYS2079
G	CYS2085
G	CYS2088
G	HIS2096
G	HIS2102
G	CYS2136
G	CYS2139
G	CYS2150
G	CYS2153
G	CYS2159
G	CYS2162
G	HIS2168
G	HIS2172
A	CYS2085
A	CYS2088
A	HIS2096
A	HIS2102
A	CYS2136
A	CYS2139
A	CYS2150
A	CYS2153
A	CYS2159
A	CYS2162
A	HIS2168
A	HIS2172
A	CYS2062
A	CYS2065
A	CYS2076
A	CYS2079

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)