7DCU
Crystal structure of HSF2 DNA-binding domain in complex with 3-site HSE DNA (21 bp)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0043565 | molecular_function | sequence-specific DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0043565 | molecular_function | sequence-specific DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0043565 | molecular_function | sequence-specific DNA binding |
Functional Information from PROSITE/UniProt
| site_id | PS00434 |
| Number of Residues | 25 |
| Details | HSF_DOMAIN HSF-type DNA-binding domain signature. LpkyFKHnNmASFVRQLNmYgFRKV |
| Chain | Residue | Details |
| A | LEU49-VAL73 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 315 |
| Details | DNA_BIND: DNA_BIND => ECO:0000250 |
| Chain | Residue | Details |
| A | VAL7-SER112 | |
| B | VAL7-SER112 | |
| C | VAL7-SER112 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS82 | |
| B | LYS82 | |
| C | LYS82 |
