7BZJ
The Discovery of Benzhydrol-Oxaborole Hybrid Derivatives as Leucyl-tRNA Synthetase Inhibitors
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0002161 | molecular_function | aminoacyl-tRNA editing activity |
A | 0004823 | molecular_function | leucine-tRNA ligase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
A | 0006429 | biological_process | leucyl-tRNA aminoacylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | binding site for residue FGX A 501 |
Chain | Residue |
A | PHE246 |
A | MET338 |
A | HIS343 |
A | ASP344 |
A | THR373 |
A | LYS389 |
A | HOH606 |
A | HOH617 |
A | HOH643 |
A | HOH660 |
A | HOH686 |
A | THR247 |
A | HOH690 |
A | HOH696 |
A | HOH701 |
A | THR248 |
A | ARG249 |
A | TYR327 |
A | VAL328 |
A | LEU329 |
A | TYR332 |
A | VAL337 |