Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | GLU75 |
| A | ASN77 |
| A | VAL80 |
| A | GLU85 |
| A | HOH409 |
| A | HOH480 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue F66 A 302 |
| Chain | Residue |
| A | GLN197 |
| A | SER200 |
| A | SER207 |
| A | VAL214 |
| A | SER215 |
| A | TRP216 |
| A | GLY217 |
| A | GLY219 |
| A | CYS220 |
| A | HOH532 |
| A | HOH577 |
| A | HOH644 |
| A | ASP194 |
| A | SER195 |
| A | CYS196 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 303 |
| Chain | Residue |
| A | VAL81 |
| A | SER101 |
| A | ASN102 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 304 |
| Chain | Residue |
| A | LYS172 |
| A | PRO176 |
| A | GLY177 |
| A | HOH401 |
| A | HOH517 |
| A | HOH653 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue DMS A 305 |
| Chain | Residue |
| A | ARG72 |
| A | ILE78 |
| A | ASN79 |
| A | VAL81 |
| A | PHE87 |
| A | VAL95 |
| A | HIS96 |
| A | HOH480 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL59-CYS64 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP194-VAL205 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS63 | |
| A | ASP107 | |
| A | SER200 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | VAL80 | |
| A | GLU85 | |
| A | ASP194 | |
| A | GLN197 | |
| A | SER200 | |
| A | GLU75 | |
| A | ASN77 | |
