Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | GLU75 |
| A | ASN77 |
| A | VAL80 |
| A | GLU85 |
| A | HOH417 |
| A | HOH472 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue F5R A 302 |
| Chain | Residue |
| A | SER200 |
| A | TRP216 |
| A | GLY217 |
| A | GLY219 |
| A | GLY227 |
| A | HOH549 |
| A | ASP194 |
| A | SER195 |
| A | CYS196 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 303 |
| Chain | Residue |
| A | ARG72 |
| A | ILE78 |
| A | ASN79 |
| A | PHE87 |
| A | VAL95 |
| A | HIS96 |
| A | HOH472 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 304 |
| Chain | Residue |
| A | PRO129 |
| A | THR130 |
| A | SER131 |
| A | SER150 |
| A | GLY151 |
| A | LYS209 |
| A | GLN211 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 305 |
| Chain | Residue |
| A | TYR45 |
| A | HIS46 |
| A | ILE78 |
| A | ASN79 |
| A | SER93 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 306 |
| Chain | Residue |
| A | ASN100 |
| A | SER101 |
| A | ASN102 |
| A | HOH412 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 307 |
| Chain | Residue |
| A | TYR28 |
| A | CYS30 |
| A | THR34 |
| A | VAL35 |
| A | HOH556 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 308 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 309 |
| Chain | Residue |
| A | CYS233 |
| A | ASN234 |
| A | VAL236 |
| A | SER237 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 310 |
| Chain | Residue |
| A | ASN54 |
| A | SER55 |
| A | LEU119 |
| A | ASP168 |
| A | LYS172 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 311 |
| Chain | Residue |
| A | GLY68 |
| A | SER153 |
| A | TYR154 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 312 |
| Chain | Residue |
| A | ALA32 |
| A | ASN33 |
| A | SER121 |
| A | ARG122 |
| A | PRO176 |
| A | HOH405 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 313 |
| Chain | Residue |
| A | ASN54 |
| A | LEU128 |
| A | SER169 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 314 |
| Chain | Residue |
| A | THR180 |
| A | SER181 |
| A | HOH565 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL59-CYS64 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP194-VAL205 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS63 | |
| A | ASP107 | |
| A | SER200 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | VAL80 | |
| A | GLU85 | |
| A | ASP194 | |
| A | GLN197 | |
| A | SER200 | |
| A | GLU75 | |
| A | ASN77 | |
