7AUK
Yeast Diphosphoinositol Polyphosphate Phosphohydrolase DDP1 in complex with 5-InsP7
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000298 | molecular_function | endopolyphosphatase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006798 | biological_process | polyphosphate catabolic process |
| A | 0008486 | molecular_function | diphosphoinositol-polyphosphate diphosphatase activity |
| A | 0015961 | biological_process | diadenosine polyphosphate catabolic process |
| A | 0016462 | molecular_function | pyrophosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0034431 | molecular_function | bis(5'-adenosyl)-hexaphosphatase activity |
| A | 0034432 | molecular_function | bis(5'-adenosyl)-pentaphosphatase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071543 | biological_process | diphosphoinositol polyphosphate metabolic process |
| A | 1901907 | biological_process | diadenosine pentaphosphate catabolic process |
| A | 1901909 | biological_process | diadenosine hexaphosphate catabolic process |
| A | 1901911 | biological_process | adenosine 5'-(hexahydrogen pentaphosphate) catabolic process |
| A | 1990174 | molecular_function | phosphodiesterase decapping endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue I7P A 201 |
| Chain | Residue |
| A | ARG32 |
| A | ARG152 |
| A | ARG171 |
| A | HOH301 |
| A | HOH302 |
| A | HOH303 |
| A | HOH306 |
| A | HOH307 |
| A | HOH313 |
| A | HOH319 |
| A | HOH320 |
| A | SER52 |
| A | HOH324 |
| A | HOH325 |
| A | HOH332 |
| A | HOH333 |
| A | HOH335 |
| A | HOH338 |
| A | SER53 |
| A | ILE60 |
| A | LYS63 |
| A | GLY64 |
| A | GLU84 |
| A | ARG102 |
| A | ARG129 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33893105, ECO:0007744|PDB:7AUQ |
| Chain | Residue | Details |
| A | SER53 | |
| A | LYS63 | |
| A | ARG152 | |
| A | ARG171 | |
| A | GLU173 | |
| A | ARG32 | |
| A | SER52 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33893105, ECO:0007744|PDB:7AUP |
| Chain | Residue | Details |
| A | GLU80 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33893105, ECO:0007744|PDB:7AUL, ECO:0007744|PDB:7AUP |
| Chain | Residue | Details |
| A | GLU84 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33893105, ECO:0007744|PDB:7AUR |
| Chain | Residue | Details |
| A | ASP100 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33893105, ECO:0007744|PDB:7AUK |
| Chain | Residue | Details |
| A | ARG102 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33893105, ECO:0007744|PDB:7AUI |
| Chain | Residue | Details |
| A | ARG129 |
