Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7A24

Assembly intermediate of the plant mitochondrial complex I

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005747	cellular_component	mitochondrial respiratory chain complex I
A	0005886	cellular_component	plasma membrane
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0010181	molecular_function	FMN binding
A	0016491	molecular_function	oxidoreductase activity
A	0045271	cellular_component	respiratory chain complex I
A	0046872	molecular_function	metal ion binding
A	0051287	molecular_function	NAD binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0055085	biological_process	transmembrane transport
A	0070469	cellular_component	respirasome
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005747	cellular_component	mitochondrial respiratory chain complex I
B	0005829	cellular_component	cytosol
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0008270	molecular_function	zinc ion binding
B	0016491	molecular_function	oxidoreductase activity
B	0045271	cellular_component	respiratory chain complex I
B	0046872	molecular_function	metal ion binding
B	0051537	molecular_function	2 iron, 2 sulfur cluster binding
B	0055085	biological_process	transmembrane transport
B	0070469	cellular_component	respirasome
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005747	cellular_component	mitochondrial respiratory chain complex I
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0009507	cellular_component	chloroplast
C	0009536	cellular_component	plastid
C	0009853	biological_process	photorespiration
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
C	0031966	cellular_component	mitochondrial membrane
C	0042773	biological_process	ATP synthesis coupled electron transport
C	0045271	cellular_component	respiratory chain complex I
C	0046872	molecular_function	metal ion binding
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
C	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0055085	biological_process	transmembrane transport
C	0070469	cellular_component	respirasome
D	0005634	cellular_component	nucleus
D	0005739	cellular_component	mitochondrion
D	0005747	cellular_component	mitochondrial respiratory chain complex I
D	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
D	0046872	molecular_function	metal ion binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
D	0055085	biological_process	transmembrane transport
D	0070469	cellular_component	respirasome
E	0005739	cellular_component	mitochondrion
E	0005747	cellular_component	mitochondrial respiratory chain complex I
E	0005886	cellular_component	plasma membrane
E	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
E	0008270	molecular_function	zinc ion binding
E	0016491	molecular_function	oxidoreductase activity
E	0046872	molecular_function	metal ion binding
E	0048038	molecular_function	quinone binding
E	0051536	molecular_function	iron-sulfur cluster binding
E	0051539	molecular_function	4 iron, 4 sulfur cluster binding
E	0055085	biological_process	transmembrane transport
E	0070469	cellular_component	respirasome
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005747	cellular_component	mitochondrial respiratory chain complex I
F	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
F	0016491	molecular_function	oxidoreductase activity
F	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
F	0055085	biological_process	transmembrane transport
F	0070469	cellular_component	respirasome
G	0005739	cellular_component	mitochondrion
G	0005747	cellular_component	mitochondrial respiratory chain complex I
G	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
G	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
G	0016491	molecular_function	oxidoreductase activity
G	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
G	0048038	molecular_function	quinone binding
G	0051287	molecular_function	NAD binding
G	0055085	biological_process	transmembrane transport
G	0070469	cellular_component	respirasome
H	0003954	molecular_function	NADH dehydrogenase activity
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005747	cellular_component	mitochondrial respiratory chain complex I
H	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
H	0009060	biological_process	aerobic respiration
H	0016020	cellular_component	membrane
H	0055085	biological_process	transmembrane transport
H	0070469	cellular_component	respirasome
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
I	0009536	cellular_component	plastid
I	0042773	biological_process	ATP synthesis coupled electron transport
I	0055085	biological_process	transmembrane transport
I	0070469	cellular_component	respirasome
J	0005739	cellular_component	mitochondrion
J	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
J	0016020	cellular_component	membrane
J	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
J	0030964	cellular_component	NADH dehydrogenase complex
J	0031966	cellular_component	mitochondrial membrane
J	0055085	biological_process	transmembrane transport
J	0070469	cellular_component	respirasome
K	0005739	cellular_component	mitochondrion
K	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
K	0016020	cellular_component	membrane
K	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
K	0030964	cellular_component	NADH dehydrogenase complex
K	0031966	cellular_component	mitochondrial membrane
K	0042773	biological_process	ATP synthesis coupled electron transport
K	0055085	biological_process	transmembrane transport
K	0070469	cellular_component	respirasome
N	0005739	cellular_component	mitochondrion
N	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N	0016020	cellular_component	membrane
N	0031966	cellular_component	mitochondrial membrane
N	0055085	biological_process	transmembrane transport
N	0070469	cellular_component	respirasome
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0005747	cellular_component	mitochondrial respiratory chain complex I
O	0006970	biological_process	response to osmotic stress
O	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
O	0009536	cellular_component	plastid
O	0009631	biological_process	cold acclimation
O	0022900	biological_process	electron transport chain
O	0050897	molecular_function	cobalt ion binding
O	0055085	biological_process	transmembrane transport
O	0070469	cellular_component	respirasome
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0005747	cellular_component	mitochondrial respiratory chain complex I
P	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
P	0070469	cellular_component	respirasome
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005747	cellular_component	mitochondrial respiratory chain complex I
Q	0009536	cellular_component	plastid
Q	0070469	cellular_component	respirasome
R	0005515	molecular_function	protein binding
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0005747	cellular_component	mitochondrial respiratory chain complex I
R	0009536	cellular_component	plastid
R	0009853	biological_process	photorespiration
R	0022904	biological_process	respiratory electron transport chain
R	0031966	cellular_component	mitochondrial membrane
R	0045271	cellular_component	respiratory chain complex I
R	0070469	cellular_component	respirasome
S	0005739	cellular_component	mitochondrion
S	0005886	cellular_component	plasma membrane
T	0005739	cellular_component	mitochondrion
T	0005747	cellular_component	mitochondrial respiratory chain complex I
T	0005759	cellular_component	mitochondrial matrix
T	0070469	cellular_component	respirasome
U	0005739	cellular_component	mitochondrion
U	0005743	cellular_component	mitochondrial inner membrane
U	0005747	cellular_component	mitochondrial respiratory chain complex I
U	0005829	cellular_component	cytosol
U	0016020	cellular_component	membrane
U	0032981	biological_process	mitochondrial respiratory chain complex I assembly
U	0050897	molecular_function	cobalt ion binding
U	0070469	cellular_component	respirasome
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0005747	cellular_component	mitochondrial respiratory chain complex I
V	0070469	cellular_component	respirasome
W	0005739	cellular_component	mitochondrion
W	0005829	cellular_component	cytosol
X	0005739	cellular_component	mitochondrion
X	0005743	cellular_component	mitochondrial inner membrane
X	0005747	cellular_component	mitochondrial respiratory chain complex I
X	0005829	cellular_component	cytosol
X	0070469	cellular_component	respirasome
Y	0005739	cellular_component	mitochondrion
Y	0005747	cellular_component	mitochondrial respiratory chain complex I
Y	0005758	cellular_component	mitochondrial intermembrane space
Y	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
Y	0009536	cellular_component	plastid
Y	0070469	cellular_component	respirasome
Z	0005576	cellular_component	extracellular region
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0005747	cellular_component	mitochondrial respiratory chain complex I
Z	0009793	biological_process	embryo development ending in seed dormancy
Z	0009853	biological_process	photorespiration
Z	0031966	cellular_component	mitochondrial membrane
Z	0045271	cellular_component	respiratory chain complex I
Z	0070469	cellular_component	respirasome
c	0005739	cellular_component	mitochondrion
c	0005747	cellular_component	mitochondrial respiratory chain complex I
c	0005829	cellular_component	cytosol
c	0009853	biological_process	photorespiration
c	0031966	cellular_component	mitochondrial membrane
c	0045271	cellular_component	respiratory chain complex I
i	0000325	cellular_component	plant-type vacuole
i	0005739	cellular_component	mitochondrion
i	0005747	cellular_component	mitochondrial respiratory chain complex I
i	0005829	cellular_component	cytosol
j	0005739	cellular_component	mitochondrion
j	0005743	cellular_component	mitochondrial inner membrane
j	0005747	cellular_component	mitochondrial respiratory chain complex I
j	0005758	cellular_component	mitochondrial intermembrane space
j	0005829	cellular_component	cytosol
j	0070469	cellular_component	respirasome
k	0000036	molecular_function	acyl carrier activity
k	0005515	molecular_function	protein binding
k	0005739	cellular_component	mitochondrion
k	0005747	cellular_component	mitochondrial respiratory chain complex I
k	0005759	cellular_component	mitochondrial matrix
k	0005829	cellular_component	cytosol
k	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
k	0006633	biological_process	fatty acid biosynthetic process
k	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
k	0055085	biological_process	transmembrane transport
k	0070469	cellular_component	respirasome
n	0000325	cellular_component	plant-type vacuole
n	0005507	molecular_function	copper ion binding
n	0005730	cellular_component	nucleolus
n	0005739	cellular_component	mitochondrion
n	0005747	cellular_component	mitochondrial respiratory chain complex I
n	0005777	cellular_component	peroxisome
n	0009853	biological_process	photorespiration
n	0031966	cellular_component	mitochondrial membrane
n	0045271	cellular_component	respiratory chain complex I
o	0005515	molecular_function	protein binding
o	0005739	cellular_component	mitochondrion
o	0016020	cellular_component	membrane
o	0031966	cellular_component	mitochondrial membrane
o	0046872	molecular_function	metal ion binding
p	0004089	molecular_function	carbonate dehydratase activity
p	0005634	cellular_component	nucleus
p	0005739	cellular_component	mitochondrion
p	0005747	cellular_component	mitochondrial respiratory chain complex I
p	0009853	biological_process	photorespiration
p	0016020	cellular_component	membrane
p	0016829	molecular_function	lyase activity
p	0031966	cellular_component	mitochondrial membrane
p	0045271	cellular_component	respiratory chain complex I
p	0046872	molecular_function	metal ion binding
p	0070207	biological_process	protein homotrimerization
q	0004089	molecular_function	carbonate dehydratase activity
q	0005634	cellular_component	nucleus
q	0005739	cellular_component	mitochondrion
q	0005747	cellular_component	mitochondrial respiratory chain complex I
q	0009853	biological_process	photorespiration
q	0016020	cellular_component	membrane
q	0016829	molecular_function	lyase activity
q	0031966	cellular_component	mitochondrial membrane
q	0045271	cellular_component	respiratory chain complex I
q	0046872	molecular_function	metal ion binding
q	0070207	biological_process	protein homotrimerization
z	0003885	molecular_function	D-arabinono-1,4-lactone oxidase activity
z	0005739	cellular_component	mitochondrion
z	0016020	cellular_component	membrane
z	0016491	molecular_function	oxidoreductase activity
z	0016633	molecular_function	galactonolactone dehydrogenase activity
z	0016899	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
z	0019853	biological_process	L-ascorbic acid biosynthetic process
z	0031966	cellular_component	mitochondrial membrane
z	0050660	molecular_function	flavin adenine dinucleotide binding
z	0071949	molecular_function	FAD binding
z	0080049	molecular_function	L-gulono-1,4-lactone dehydrogenase activity

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDTVEIVMAI

Chain	Residue	Details
k	ASP74-ILE89

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP

Chain	Residue	Details
D	CYS123-PRO134
D	CYS162-PRO173

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
G	LEU47-LYS58

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREvwDMFgvsfinHpdlRrIL

Chain	Residue	Details
F	GLU112-LEU133

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYhsrlsiaGnCRmC

Chain	Residue	Details
C	PRO103-CYS120

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
C	CYS170-GLN182

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCVrF

Chain	Residue	Details
C	ARG217-PHE227

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALLES

Chain	Residue	Details
A	GLY223-SER238

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
A	GLU400-GLY411

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpLaDGLKLIlKE

Chain	Residue	Details
H	GLY47-GLU62

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLPEAEaeLVa.G

Chain	Residue	Details
H	PRO202-GLY215

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DglFSvgemeCMGcCvnAP

Chain	Residue	Details
B	ASP161-PRO179

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
E	GLY174-PRO190

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
z	TYR68-PHE84
p	HIS130
p	HIS135
p	ASN209
I	PHE411-VAL431
I	LEU467-PHE487
q	GLN101
q	HIS107
q	HIS130
q	HIS135
q	ASN209
p	ARG86
p	GLN101
p	HIS107

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU01184

Chain	Residue	Details
C	HIS166
C	CYS170
C	CYS173
C	CYS179

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)