6USR
Telomerase Reverse Transcriptase ternary complex, TERT:DNA:dGpCpp
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000781 | cellular_component | chromosome, telomeric region |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003721 | molecular_function | telomerase RNA reverse transcriptase activity |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005694 | cellular_component | chromosome |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| A | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 602 |
| Chain | Residue |
| A | ASP251 |
| A | ILE252 |
| A | ASP343 |
| A | G2P604 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 603 |
| Chain | Residue |
| A | HOH714 |
| E | DA15 |
| A | ASP251 |
| A | ASP343 |
| A | ASP344 |
| A | G2P604 |
| A | K605 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue G2P A 604 |
| Chain | Residue |
| A | LYS189 |
| A | ARG194 |
| A | ASP251 |
| A | ILE252 |
| A | ARG253 |
| A | ASP254 |
| A | ALA255 |
| A | TYR256 |
| A | GLN308 |
| A | GLY309 |
| A | ASP343 |
| A | MG602 |
| A | MG603 |
| A | K605 |
| A | HOH702 |
| A | HOH704 |
| E | DA15 |
| F | C1 |
| F | U2 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue K A 605 |
| Chain | Residue |
| A | LYS189 |
| A | MG603 |
| A | G2P604 |
| A | HOH726 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue MG F 101 |
| Chain | Residue |
| F | DC11 |
