Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006570 | biological_process | tyrosine metabolic process |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042403 | biological_process | thyroid hormone metabolic process |
| A | 0072545 | molecular_function | L-tyrosine binding |
| A | 0140616 | molecular_function | iodotyrosine deiodinase activity |
| B | 0006570 | biological_process | tyrosine metabolic process |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042403 | biological_process | thyroid hormone metabolic process |
| B | 0072545 | molecular_function | L-tyrosine binding |
| B | 0140616 | molecular_function | iodotyrosine deiodinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue FMN A 301 |
| Chain | Residue |
| A | LYS12 |
| A | LYS173 |
| A | TYR174 |
| A | ARG176 |
| A | IYR302 |
| A | CL303 |
| A | HOH425 |
| A | HOH436 |
| A | HOH437 |
| A | HOH440 |
| B | PRO38 |
| A | THR13 |
| B | SER39 |
| B | GLY40 |
| B | TYR112 |
| B | SER116 |
| A | ARG15 |
| A | TRP82 |
| A | PHE88 |
| A | VAL136 |
| A | PRO137 |
| A | TYR138 |
| A | THR139 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue IYR A 302 |
| Chain | Residue |
| A | GLU68 |
| A | TYR72 |
| A | TRP82 |
| A | LEU83 |
| A | LYS92 |
| A | TYR138 |
| A | THR139 |
| A | FMN301 |
| A | HOH493 |
| B | GLY40 |
| B | MET41 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 303 |
| Chain | Residue |
| A | ARG11 |
| A | THR13 |
| A | PRO137 |
| A | FMN301 |
| B | PRO38 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 304 |
| Chain | Residue |
| A | ARG157 |
| A | HOH457 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 305 |
| Chain | Residue |
| A | ARG15 |
| A | ARG16 |
| A | PRO170 |
| A | LYS171 |
| A | HOH584 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 306 |
| Chain | Residue |
| A | TRP82 |
| A | LYS86 |
| B | ASN42 |
| B | ASN177 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 307 |
| Chain | Residue |
| A | GLU54 |
| A | GLY58 |
| A | HOH469 |
| A | HOH477 |
| site_id | AC8 |
| Number of Residues | 23 |
| Details | binding site for residue FMN B 301 |
| Chain | Residue |
| A | PRO38 |
| A | SER39 |
| A | GLY40 |
| A | TYR112 |
| A | SER116 |
| B | LYS12 |
| B | THR13 |
| B | ARG15 |
| B | TRP82 |
| B | PHE88 |
| B | VAL136 |
| B | PRO137 |
| B | TYR138 |
| B | THR139 |
| B | LYS173 |
| B | TYR174 |
| B | ARG176 |
| B | IYR302 |
| B | CL303 |
| B | HOH422 |
| B | HOH426 |
| B | HOH440 |
| B | HOH470 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | binding site for residue IYR B 302 |
| Chain | Residue |
| A | GLY40 |
| A | MET41 |
| B | GLU68 |
| B | TYR72 |
| B | LEU83 |
| B | LYS92 |
| B | TYR138 |
| B | THR139 |
| B | FMN301 |
| B | HOH460 |
| B | HOH471 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 303 |
| Chain | Residue |
| A | PRO38 |
| B | ARG11 |
| B | THR13 |
| B | PRO137 |
| B | FMN301 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 304 |
| Chain | Residue |
| A | ASN42 |
| A | ASN177 |
| B | TRP82 |
| B | LYS86 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue IYR B 305 |
| Chain | Residue |
| A | HOH497 |
| B | GLU73 |
| B | ASN74 |
| B | ARG114 |
| B | GLU115 |
| B | HOH430 |
| A | ARG114 |
| A | GLU115 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | ARG11 | |
| B | PRO38 | |
| B | SER39 | |
| B | ARG176 | |
| A | ARG11 | |
| A | PRO38 | |
| A | SER39 | |
| A | ARG176 | |
| Chain | Residue | Details |
| A | TYR72 | |
| A | LYS92 | |
| B | MET41 | |
| B | GLU68 | |
| B | TYR72 | |
| B | LYS92 | |
| A | MET41 | |
| A | GLU68 | |
