6TQ1
N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 5-(1-(1,3-dimethoxypropan-2-yl)-5-morpholino-1H-benzo[d]imidazol-2-yl)-1,3-dimethylpyridin-2(1H)-one
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFrqpvDavklglpDYHkiIkqpMdmgtIkrrlenny..Ywaasecmqdfnt.MftNCyiY |
| Chain | Residue | Details |
| AAA | ALA96-TYR155 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:37731000, ECO:0007744|PDB:8SB6 |
| Chain | Residue | Details |
| AAA | ASP112 | |
| CCC | TYR155 | |
| CCC | ASN156 | |
| CCC | LYS157 | |
| AAA | TYR155 | |
| AAA | ASN156 | |
| AAA | LYS157 | |
| BBB | ASP112 | |
| BBB | TYR155 | |
| BBB | ASN156 | |
| BBB | LYS157 | |
| CCC | ASP112 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20048151, ECO:0007744|PDB:2DVQ, ECO:0007744|PDB:2DVS |
| Chain | Residue | Details |
| AAA | ASP160 | |
| AAA | ASP161 | |
| BBB | ASP160 | |
| BBB | ASP161 | |
| CCC | ASP160 | |
| CCC | ASP161 |
