6T6P

Crystal structure of Klebsiella pneumoniae FabG2(NADH-dependent) at 1.57 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004316	molecular_function	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
A	0016491	molecular_function	oxidoreductase activity
B	0000166	molecular_function	nucleotide binding
B	0004316	molecular_function	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
B	0016491	molecular_function	oxidoreductase activity
C	0000166	molecular_function	nucleotide binding
C	0004316	molecular_function	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
C	0016491	molecular_function	oxidoreductase activity
D	0000166	molecular_function	nucleotide binding
D	0004316	molecular_function	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
D	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue PO4 A 301

Chain	Residue
A	HIS98
A	LYS99
C	ARG128
C	LYS172
C	LYS173
C	HOH517
D	GOL305

---

site_id	AC2
Number of Residues	5
Details	binding site for residue PO4 A 302

Chain	Residue
A	ALA78
A	GLY80
D	ARG49
A	ARG31
A	GLU77

---

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL A 303

Chain	Residue
A	ARG37
A	CYS60
A	ASN61
A	ILE62
A	HOH451

---

site_id	AC4
Number of Residues	8
Details	binding site for residue GOL A 304

Chain	Residue
A	LYS164
A	ARG168
A	GLY233
A	HOH426
B	LEU144
B	HOH434
C	GLY241
C	VAL243

---

site_id	AC5
Number of Residues	5
Details	binding site for residue GOL A 305

Chain	Residue
A	ALA14
A	HIS40
A	ALA43
A	SER47
A	HOH499

---

site_id	AC6
Number of Residues	7
Details	binding site for residue GOL A 306

Chain	Residue
A	ASN237
A	MET242
A	VAL243
A	LEU244
A	HOH402
A	HOH405
A	HOH408

---

site_id	AC7
Number of Residues	7
Details	binding site for residue GOL A 307

Chain	Residue
A	LYS65
A	HOH435
A	HOH443
B	HIS98
B	LYS99
B	LEU100
B	THR101

---

site_id	AC8
Number of Residues	8
Details	binding site for residue GOL A 308

Chain	Residue
A	HIS98
A	LYS99
A	LEU100
A	THR101
A	HOH407
B	LYS65
B	ILE125
B	HOH449

---

site_id	AC9
Number of Residues	4
Details	binding site for residue PO4 B 301

Chain	Residue
B	ARG31
B	GLU77
B	ALA78
C	ARG49

---

site_id	AD1
Number of Residues	5
Details	binding site for residue GOL B 302

Chain	Residue
B	ALA14
B	HIS40
B	ALA43
B	SER47
B	HOH431

---

site_id	AD2
Number of Residues	8
Details	binding site for residue GOL B 303

Chain	Residue
B	ALA141
B	TRP143
B	ASN237
B	MET242
B	VAL243
B	LEU244
B	HOH404
B	HOH456

---

site_id	AD3
Number of Residues	9
Details	binding site for residue GOL B 304

Chain	Residue
A	LEU144
A	HOH437
B	LYS164
B	ARG168
B	GLY233
B	HOH424
B	HOH527
D	GLY241
D	VAL243

---

site_id	AD4
Number of Residues	7
Details	binding site for residue GOL B 305

Chain	Residue
A	ARG128
B	HIS98
B	LYS99
C	PO4301
D	ARG128
D	LYS172
D	LYS173

---

site_id	AD5
Number of Residues	9
Details	binding site for residue PO4 C 301

Chain	Residue
A	ARG128
A	LYS172
A	LYS173
B	GOL305
C	HIS98
C	LYS99
C	HOH405
C	HOH466
D	ARG128

---

site_id	AD6
Number of Residues	5
Details	binding site for residue GOL C 302

Chain	Residue
C	ALA14
C	HIS40
C	ALA43
C	SER47
C	HOH493

---

site_id	AD7
Number of Residues	9
Details	binding site for residue GOL C 303

Chain	Residue
A	GLY241
A	VAL243
C	LYS164
C	ARG168
C	GLY233
C	HOH429
C	HOH442
C	HOH545
D	LEU144

---

site_id	AD8
Number of Residues	7
Details	binding site for residue GOL C 304

Chain	Residue
C	ALA141
C	ASN237
C	MET242
C	VAL243
C	LEU244
C	HOH412
C	HOH413

---

site_id	AD9
Number of Residues	5
Details	binding site for residue GOL C 305

Chain	Residue
C	ARG37
C	CYS60
C	ASN61
C	ILE62
C	HOH404

---

site_id	AE1
Number of Residues	7
Details	binding site for residue GOL C 306

Chain	Residue
C	HIS98
C	LYS99
C	LEU100
C	HOH425
D	LYS65
D	GLN121
D	ILE125

---

site_id	AE2
Number of Residues	5
Details	binding site for residue GOL D 301

Chain	Residue
D	ALA14
D	HIS40
D	ALA43
D	SER47
D	HOH424

---

site_id	AE3
Number of Residues	8
Details	binding site for residue GOL D 302

Chain	Residue
D	ALA141
D	TRP143
D	ASN237
D	MET242
D	VAL243
D	LEU244
D	HOH401
D	HOH408

---

site_id	AE4
Number of Residues	9
Details	binding site for residue GOL D 303

Chain	Residue
B	GLY241
B	VAL243
C	LEU144
D	LYS164
D	ARG168
D	GLY233
D	HOH431
D	HOH455
D	HOH530

---

site_id	AE5
Number of Residues	4
Details	binding site for residue GOL D 304

Chain	Residue
D	SER59
D	GLN67
D	ALA70
D	GLN74

---

site_id	AE6
Number of Residues	9
Details	binding site for residue GOL D 305

Chain	Residue
A	PO4301
B	ARG128
B	LYS172
B	LYS173
C	ARG128
D	HIS98
D	LYS99
D	HOH454
D	HOH537

---

site_id	AE7
Number of Residues	7
Details	binding site for residue GOL D 306

Chain	Residue
C	LYS65
C	HOH452
D	HIS98
D	LYS99
D	LEU100
D	THR101
D	HOH533

---

Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. AsaswlgnvgQtnYSASKAGVvGMTkTAC

Chain	Residue	Details
A	ALA139-CYS167

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