6T1U
Cytochrome P450 reductase from Candida tropicalis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003958 | molecular_function | NADPH-hemoprotein reductase activity |
| A | 0003959 | molecular_function | NADPH dehydrogenase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005741 | cellular_component | mitochondrial outer membrane |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006696 | biological_process | ergosterol biosynthetic process |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016126 | biological_process | sterol biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003958 | molecular_function | NADPH-hemoprotein reductase activity |
| B | 0003959 | molecular_function | NADPH dehydrogenase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005741 | cellular_component | mitochondrial outer membrane |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005789 | cellular_component | endoplasmic reticulum membrane |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006696 | biological_process | ergosterol biosynthetic process |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016126 | biological_process | sterol biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | binding site for residue FAD A 700 |
| Chain | Residue |
| A | TYR118 |
| A | TYR440 |
| A | SER441 |
| A | THR456 |
| A | ALA457 |
| A | VAL458 |
| A | GLU460 |
| A | VAL470 |
| A | THR471 |
| A | GLY472 |
| A | VAL473 |
| A | HIS303 |
| A | VAL474 |
| A | THR475 |
| A | ASP677 |
| A | TRP679 |
| A | FMN701 |
| A | HOH835 |
| A | HOH862 |
| A | HOH874 |
| A | HOH877 |
| A | HOH878 |
| A | GLY363 |
| A | HOH961 |
| A | HOH1009 |
| A | HOH1018 |
| A | HOH1021 |
| A | HOH1086 |
| A | HOH1119 |
| A | HOH1144 |
| A | PRO364 |
| A | LYS404 |
| A | PHE405 |
| A | ASN406 |
| A | ARG438 |
| A | TYR439 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | binding site for residue FMN A 701 |
| Chain | Residue |
| A | SER65 |
| A | GLN66 |
| A | THR67 |
| A | GLY68 |
| A | THR69 |
| A | ALA70 |
| A | ALA116 |
| A | THR117 |
| A | TYR118 |
| A | GLY119 |
| A | GLY121 |
| A | LEU151 |
| A | GLY152 |
| A | ASN153 |
| A | TYR156 |
| A | PHE158 |
| A | PHE159 |
| A | ASN160 |
| A | ASP186 |
| A | LEU191 |
| A | VAL678 |
| A | FAD700 |
| A | HOH910 |
| A | HOH945 |
| A | HOH946 |
| A | HOH1032 |
| site_id | AC3 |
| Number of Residues | 36 |
| Details | binding site for residue FAD B 700 |
| Chain | Residue |
| B | HIS303 |
| B | GLY363 |
| B | PRO364 |
| B | LYS404 |
| B | PHE405 |
| B | ASN406 |
| B | ARG438 |
| B | TYR439 |
| B | TYR440 |
| B | SER441 |
| B | THR456 |
| B | ALA457 |
| B | VAL458 |
| B | GLU460 |
| B | VAL470 |
| B | THR471 |
| B | GLY472 |
| B | VAL473 |
| B | VAL474 |
| B | THR475 |
| B | ASP677 |
| B | TRP679 |
| B | FMN701 |
| B | HOH821 |
| B | HOH853 |
| B | HOH871 |
| B | HOH884 |
| B | HOH889 |
| B | HOH921 |
| B | HOH945 |
| B | HOH996 |
| B | HOH1054 |
| B | HOH1145 |
| B | HOH1148 |
| B | HOH1153 |
| B | HOH1186 |
| site_id | AC4 |
| Number of Residues | 25 |
| Details | binding site for residue FMN B 701 |
| Chain | Residue |
| B | GLN66 |
| B | THR67 |
| B | GLY68 |
| B | THR69 |
| B | ALA70 |
| B | ALA116 |
| B | THR117 |
| B | TYR118 |
| B | GLY119 |
| B | GLY121 |
| B | LEU151 |
| B | GLY152 |
| B | ASN153 |
| B | TYR156 |
| B | PHE158 |
| B | PHE159 |
| B | ASN160 |
| B | ASP186 |
| B | LEU191 |
| B | FAD700 |
| B | HOH863 |
| B | HOH880 |
| B | HOH1069 |
| B | HOH1071 |
| B | SER65 |
