6RUZ

NADH-dependent Coenzyme A Disulfide Reductase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016491	molecular_function	oxidoreductase activity
A	0050660	molecular_function	flavin adenine dinucleotide binding
B	0000166	molecular_function	nucleotide binding
B	0016491	molecular_function	oxidoreductase activity
B	0050660	molecular_function	flavin adenine dinucleotide binding
C	0000166	molecular_function	nucleotide binding
C	0016491	molecular_function	oxidoreductase activity
C	0050660	molecular_function	flavin adenine dinucleotide binding
D	0000166	molecular_function	nucleotide binding
D	0016491	molecular_function	oxidoreductase activity
D	0050660	molecular_function	flavin adenine dinucleotide binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	33
Details	binding site for residue FAD A 501

Chain	Residue
A	VAL8
A	ALA43
A	CYS44
A	HIS79
A	GLU80
A	VAL81
A	ALA112
A	THR113
A	GLY114
A	ALA115
A	LEU133
A	GLY9
A	ARG134
A	TYR159
A	GLY280
A	ASP281
A	PRO297
A	LEU298
A	GLY299
A	ASP300
A	ALA302
A	COA502
A	VAL11
A	HOH609
B	TYR424
B	ALA425
B	PRO426
A	ALA12
A	GLY13
A	TYR33
A	GLU34
A	LYS35
A	TYR41

---

site_id	AC2
Number of Residues	17
Details	binding site for residue COA A 502

Chain	Residue
A	VAL11
A	ALA12
A	ALA15
A	ALA19
A	LYS20
A	ARG23
A	SER40
A	TYR41
A	CYS44
A	ARG63
A	GLY299
A	ASN303
A	ARG307
A	FAD501
B	GLN359
B	GLN441
B	ALA442

---

site_id	AC3
Number of Residues	32
Details	binding site for residue FAD B 501

Chain	Residue
A	TYR424
A	ALA425
A	PRO426
B	VAL8
B	GLY9
B	VAL11
B	ALA12
B	GLY13
B	TYR33
B	GLU34
B	LYS35
B	TYR41
B	ALA43
B	CYS44
B	HIS79
B	VAL81
B	ALA112
B	THR113
B	GLY114
B	ALA115
B	LEU133
B	ARG134
B	TYR159
B	GLY280
B	ASP281
B	PRO297
B	LEU298
B	GLY299
B	ASP300
B	ALA302
B	COA502
B	HOH612

---

site_id	AC4
Number of Residues	32
Details	binding site for residue FAD C 501

Chain	Residue
C	ARG134
C	TYR159
C	ALA279
C	GLY280
C	ASP281
C	PRO297
C	LEU298
C	GLY299
C	ASP300
C	ALA302
C	COA502
C	HOH608
D	TYR424
D	ALA425
D	PRO426
C	VAL8
C	GLY9
C	VAL11
C	ALA12
C	GLY13
C	TYR33
C	GLU34
C	LYS35
C	ALA43
C	CYS44
C	HIS79
C	VAL81
C	ALA112
C	THR113
C	GLY114
C	ALA115
C	LEU133

---

site_id	AC5
Number of Residues	31
Details	binding site for residue FAD D 501

Chain	Residue
C	TYR424
C	ALA425
D	VAL8
D	GLY9
D	VAL11
D	ALA12
D	GLY13
D	TYR33
D	GLU34
D	LYS35
D	ALA43
D	CYS44
D	HIS79
D	GLU80
D	VAL81
D	ALA112
D	THR113
D	GLY114
D	ALA115
D	LEU133
D	ARG134
D	TYR159
D	ALA279
D	GLY280
D	ASP281
D	PRO297
D	LEU298
D	GLY299
D	ASP300
D	ALA302
D	COA502

---

site_id	AC6
Number of Residues	23
Details	binding site for Di-peptide COA B 502 and CYS B 44

Chain	Residue
A	GLN359
A	TYR424
A	PRO426
A	VAL431
A	GLN441
A	ALA442
B	VAL11
B	ALA12
B	ALA15
B	LYS20
B	ARG23
B	SER40
B	TYR41
B	GLY42
B	ALA43
B	GLY45
B	LEU46
B	PRO47
B	ARG63
B	GLY299
B	ASN303
B	ARG307
B	FAD501

---

site_id	AC7
Number of Residues	25
Details	binding site for Di-peptide COA C 502 and CYS C 44

Chain	Residue
C	VAL11
C	ALA12
C	ALA15
C	SER16
C	ALA19
C	LYS20
C	ARG23
C	SER40
C	TYR41
C	GLY42
C	ALA43
C	GLY45
C	LEU46
C	PRO47
C	ARG63
C	GLY299
C	ASN303
C	ARG307
C	FAD501
D	GLN359
D	TYR424
D	VAL431
D	ILE437
D	GLN441
D	ALA442

---

site_id	AC8
Number of Residues	25
Details	binding site for Di-peptide COA D 502 and CYS D 44

Chain	Residue
C	GLN359
C	TYR424
C	PRO426
C	VAL431
C	ILE437
C	GLN441
C	ALA442
D	VAL11
D	ALA15
D	ALA19
D	LYS20
D	ARG23
D	SER40
D	TYR41
D	GLY42
D	ALA43
D	GLY45
D	LEU46
D	PRO47
D	ALA62
D	ARG63
D	GLY299
D	ASN303
D	ARG307
D	FAD501

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