6Q1L
Crystal structure of oxidized iodotyrosine deiodinase (IYD) bound to FMN and 3-iodo-L-tyrosine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006570 | biological_process | tyrosine metabolic process |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042403 | biological_process | thyroid hormone metabolic process |
| A | 0072545 | molecular_function | L-tyrosine binding |
| A | 0140616 | molecular_function | iodotyrosine deiodinase activity |
| B | 0006570 | biological_process | tyrosine metabolic process |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042403 | biological_process | thyroid hormone metabolic process |
| B | 0072545 | molecular_function | L-tyrosine binding |
| B | 0140616 | molecular_function | iodotyrosine deiodinase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0007744|PDB:6PZ0, ECO:0007744|PDB:6Q1B, ECO:0007744|PDB:6Q1L, ECO:0007744|PDB:6TYK |
| Chain | Residue | Details |
| B | ARG11 | |
| B | PRO38 | |
| B | SER39 | |
| B | ARG176 | |
| A | ARG11 | |
| A | PRO38 | |
| A | SER39 | |
| A | ARG176 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:34748729, ECO:0007744|PDB:6PZ0, ECO:0007744|PDB:6TYK |
| Chain | Residue | Details |
| A | TYR72 | |
| A | LYS92 | |
| B | MET41 | |
| B | GLU68 | |
| B | TYR72 | |
| B | LYS92 | |
| A | MET41 | |
| A | GLU68 |
