6P4C

HyHEL10 Fab carrying four heavy chain mutations (HyHEL10-4x): L4F, Y33H, S56N, and Y58F

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0005615	cellular_component	extracellular space
L	0006955	biological_process	immune response

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue CL L 301

Chain	Residue
L	VAL13
L	THR14
L	ASN17

---

site_id	AC2
Number of Residues	3
Details	binding site for residue CL L 302

Chain	Residue
L	LEU181
L	THR182
L	GLU185

---

site_id	AC3
Number of Residues	5
Details	binding site for residue CL L 303

Chain	Residue
L	SER191
L	THR193
L	LYS149
L	ASP151
L	GLY152

---

site_id	AC4
Number of Residues	3
Details	binding site for residue CL H 301

Chain	Residue
H	ASP27
H	THR86
H	THR87

---

site_id	AC5
Number of Residues	4
Details	binding site for residue CL H 302

Chain	Residue
H	TYR145
H	GLU148
H	PRO149
H	VAL150

---

site_id	AC6
Number of Residues	3
Details	binding site for residue CL H 303

Chain	Residue
H	ASN155
H	SER156
H	ASN196

---

site_id	AC7
Number of Residues	1
Details	binding site for residue CL H 304

Chain	Residue
H	GLY26

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

---