6O7H

Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004519	molecular_function	endonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0016740	molecular_function	transferase activity
A	0042802	molecular_function	identical protein binding
A	0051607	biological_process	defense response to virus
B	0003723	molecular_function	RNA binding
B	0051607	biological_process	defense response to virus
C	0003723	molecular_function	RNA binding
C	0004519	molecular_function	endonuclease activity
C	0051607	biological_process	defense response to virus
D	0003723	molecular_function	RNA binding
D	0004519	molecular_function	endonuclease activity
D	0051607	biological_process	defense response to virus
E	0003723	molecular_function	RNA binding
E	0005515	molecular_function	protein binding
E	0051607	biological_process	defense response to virus
F	0003723	molecular_function	RNA binding
F	0051607	biological_process	defense response to virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 801

Chain	Residue
A	CYS389
A	CYS392
A	CYS413
A	CYS416

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN C 301

Chain	Residue
C	HIS111
C	CYS113
C	CYS122
C	CYS125

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site_id	AC3
Number of Residues	4
Details	binding site for residue ZN D 301

Chain	Residue
D	CYS113
D	CYS122
D	CYS125
D	HIS111

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site_id	AC4
Number of Residues	5
Details	binding site for residue G H 101

Chain	Residue
A	ASP628
A	ARG630
C	ASN106
E	PHE145
H	C35

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