6NPM
Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0003700 | molecular_function | DNA-binding transcription factor activity |
A | 0006275 | biological_process | regulation of DNA replication |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
A | 0042025 | cellular_component | host cell nucleus |
A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
B | 0003677 | molecular_function | DNA binding |
B | 0003700 | molecular_function | DNA-binding transcription factor activity |
B | 0006275 | biological_process | regulation of DNA replication |
B | 0006355 | biological_process | regulation of DNA-templated transcription |
B | 0042025 | cellular_component | host cell nucleus |
B | 0045893 | biological_process | positive regulation of DNA-templated transcription |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 14 |
Details | binding site for residue KVD B 701 |
Chain | Residue |
B | ASN480 |
B | THR590 |
B | HOH819 |
B | HOH831 |
B | HOH833 |
B | HOH915 |
B | ILE481 |
B | GLY484 |
B | SER516 |
B | ASN519 |
B | LEU520 |
B | LEU582 |
B | THR585 |
B | LYS586 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: For site-specific DNA endonuclease activity => ECO:0000269|PubMed:33482082 |
Chain | Residue | Details |
A | TYR518 | |
B | TYR518 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: covalent => ECO:0000269|PubMed:33482082 |
Chain | Residue | Details |
A | TYR518 | |
B | TYR518 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | SITE: Interaction dimer-dimer => ECO:0000269|PubMed:31142669 |
Chain | Residue | Details |
A | ARG491 | |
B | ARG491 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | SITE: Interaction dimer-dimer. Required for episome maintenance and generation of immortalized B cells in the host => ECO:0000269|PubMed:31142669, ECO:0000269|PubMed:33482082 |
Chain | Residue | Details |
A | TYR518 | |
B | TYR518 |