6MS8

Crystal Structure of Chalcone Isomerase from Medicago Truncatula Complexed with (2S) Naringenin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009813	biological_process	flavonoid biosynthetic process
A	0016853	molecular_function	isomerase activity
A	0016872	molecular_function	intramolecular lyase activity
A	0045430	molecular_function	chalcone isomerase activity
B	0009813	biological_process	flavonoid biosynthetic process
B	0016853	molecular_function	isomerase activity
B	0016872	molecular_function	intramolecular lyase activity
B	0045430	molecular_function	chalcone isomerase activity
C	0009813	biological_process	flavonoid biosynthetic process
C	0016853	molecular_function	isomerase activity
C	0016872	molecular_function	intramolecular lyase activity
C	0045430	molecular_function	chalcone isomerase activity
D	0009813	biological_process	flavonoid biosynthetic process
D	0016853	molecular_function	isomerase activity
D	0016872	molecular_function	intramolecular lyase activity
D	0045430	molecular_function	chalcone isomerase activity
E	0009813	biological_process	flavonoid biosynthetic process
E	0016853	molecular_function	isomerase activity
E	0016872	molecular_function	intramolecular lyase activity
E	0045430	molecular_function	chalcone isomerase activity
F	0009813	biological_process	flavonoid biosynthetic process
F	0016853	molecular_function	isomerase activity
F	0016872	molecular_function	intramolecular lyase activity
F	0045430	molecular_function	chalcone isomerase activity
G	0009813	biological_process	flavonoid biosynthetic process
G	0016853	molecular_function	isomerase activity
G	0016872	molecular_function	intramolecular lyase activity
G	0045430	molecular_function	chalcone isomerase activity
H	0009813	biological_process	flavonoid biosynthetic process
H	0016853	molecular_function	isomerase activity
H	0016872	molecular_function	intramolecular lyase activity
H	0045430	molecular_function	chalcone isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue NAR A 301

Chain	Residue
A	ARG37
A	VAL111
A	ASN114
A	SER193
A	MET194
A	HOH410
A	PHE48
A	THR49
A	ILE51
A	VAL96
A	LEU102
A	GLN106
A	TYR107
A	LYS110

---

site_id	AC2
Number of Residues	10
Details	binding site for residue NAR D 301

Chain	Residue
D	ARG37
D	PHE48
D	THR49
D	ILE51
D	VAL96
D	TYR107
D	VAL111
D	SER193
D	MET194
D	VAL200

---

site_id	AC3
Number of Residues	10
Details	binding site for residue NAR E 301

Chain	Residue
E	ARG37
E	ILE39
E	THR49
E	ILE51
E	VAL96
E	GLN106
E	TYR107
E	LYS110
E	SER193
E	MET194

---

site_id	AC4
Number of Residues	8
Details	binding site for residue NAR F 301

Chain	Residue
F	ARG37
F	PHE48
F	THR49
F	ILE51
F	VAL96
F	TYR107
F	VAL111
F	SER193

---

site_id	AC5
Number of Residues	13
Details	binding site for residue NAR G 301

Chain	Residue
G	ARG37
G	ILE39
G	PHE48
G	THR49
G	ILE51
G	VAL96
G	GLN106
G	TYR107
G	LYS110
G	ASN114
G	SER193
G	MET194
G	VAL200

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