6MHU

Nucleotide-free Cryo-EM Structure of E.coli LptB2FG Transporter

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0015920	biological_process	lipopolysaccharide transport
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055085	biological_process	transmembrane transport
A	1990351	cellular_component	transporter complex
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0015920	biological_process	lipopolysaccharide transport
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055085	biological_process	transmembrane transport
B	1990351	cellular_component	transporter complex
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0015920	biological_process	lipopolysaccharide transport
F	0016020	cellular_component	membrane
F	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
F	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
F	0055085	biological_process	transmembrane transport
F	1990351	cellular_component	transporter complex
G	0005515	molecular_function	protein binding
G	0005886	cellular_component	plasma membrane
G	0015920	biological_process	lipopolysaccharide transport
G	0016020	cellular_component	membrane
G	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
G	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
G	0055085	biological_process	transmembrane transport
G	1990351	cellular_component	transporter complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue JSG G 401

Chain	Residue
F	PHE26
G	ASP37
G	LYS62
G	PHE67
G	TYR141
G	TYR320
F	GLN29
F	ARG33
F	LEU66
F	MET303
F	TYR306
F	LEU307
G	SER30
G	LYS34

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Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGERRRVEIARAL

Chain	Residue	Details
A	LEU138-LEU152

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00434

Chain	Residue	Details
G	LEU300-SER314
G	ARG358-SER360
A	GLY36
B	GLY36

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site_id	SWS_FT_FI2
Number of Residues	120
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
G	ILE15-PHE35
G	VAL64-ALA84
G	LEU104-VAL124
G	ILE279-PRO299
G	PHE315-ILE335
G	PRO337-MET357

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site_id	SWS_FT_FI3
Number of Residues	181
Details	TOPO_DOM: Periplasmic => ECO:0000255

Chain	Residue	Details
G	VAL36-ASP63
G	ALA125-LYS278
G	PRO336

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