6LU8

Cryo-EM structure of a human pre-60S ribosomal subunit - state A

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0003723	molecular_function	RNA binding
1	0003924	molecular_function	GTPase activity
1	0005525	molecular_function	GTP binding
1	0005634	cellular_component	nucleus
1	0005730	cellular_component	nucleolus
1	0008150	biological_process	biological_process
1	0016020	cellular_component	membrane
1	0042254	biological_process	ribosome biogenesis
3	0000055	biological_process	ribosomal large subunit export from nucleus
3	0003723	molecular_function	RNA binding
3	0005634	cellular_component	nucleus
3	0005654	cellular_component	nucleoplasm
3	0005730	cellular_component	nucleolus
3	0005737	cellular_component	cytoplasm
3	0015031	biological_process	protein transport
3	0016020	cellular_component	membrane
3	0030674	molecular_function	protein-macromolecule adaptor activity
3	0032092	biological_process	positive regulation of protein binding
3	0043023	molecular_function	ribosomal large subunit binding
3	1902680	biological_process	positive regulation of RNA biosynthetic process
3	1904751	biological_process	positive regulation of protein localization to nucleolus
4	0000079	biological_process	regulation of cyclin-dependent protein serine/threonine kinase activity
4	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
4	0001649	biological_process	osteoblast differentiation
4	0003723	molecular_function	RNA binding
4	0003924	molecular_function	GTPase activity
4	0005515	molecular_function	protein binding
4	0005525	molecular_function	GTP binding
4	0005634	cellular_component	nucleus
4	0005654	cellular_component	nucleoplasm
4	0005730	cellular_component	nucleolus
4	0005737	cellular_component	cytoplasm
4	0005829	cellular_component	cytosol
4	0008156	biological_process	negative regulation of DNA replication
4	0008285	biological_process	negative regulation of cell population proliferation
4	0016020	cellular_component	membrane
4	0022408	biological_process	negative regulation of cell-cell adhesion
4	0030336	biological_process	negative regulation of cell migration
4	0031397	biological_process	negative regulation of protein ubiquitination
4	0031965	cellular_component	nuclear membrane
4	0033342	biological_process	negative regulation of collagen binding
4	0042254	biological_process	ribosome biogenesis
4	0042273	biological_process	ribosomal large subunit biogenesis
4	0048471	cellular_component	perinuclear region of cytoplasm
4	0050821	biological_process	protein stabilization
4	1990275	molecular_function	preribosome binding
6	0000054	biological_process	ribosomal subunit export from nucleus
6	0000460	biological_process	maturation of 5.8S rRNA
6	0000470	biological_process	maturation of LSU-rRNA
6	0003743	molecular_function	translation initiation factor activity
6	0005515	molecular_function	protein binding
6	0005634	cellular_component	nucleus
6	0005638	cellular_component	lamin filament
6	0005654	cellular_component	nucleoplasm
6	0005730	cellular_component	nucleolus
6	0005737	cellular_component	cytoplasm
6	0005829	cellular_component	cytosol
6	0005882	cellular_component	intermediate filament
6	0006110	biological_process	regulation of glycolytic process
6	0006412	biological_process	translation
6	0006413	biological_process	translational initiation
6	0030687	cellular_component	preribosome, large subunit precursor
6	0032868	biological_process	response to insulin
6	0035195	biological_process	miRNA-mediated post-transcriptional gene silencing
6	0035278	biological_process	miRNA-mediated gene silencing by inhibition of translation
6	0042254	biological_process	ribosome biogenesis
6	0042256	biological_process	cytosolic ribosome assembly
6	0042273	biological_process	ribosomal large subunit biogenesis
6	0042304	biological_process	regulation of fatty acid biosynthetic process
6	0043022	molecular_function	ribosome binding
6	0043023	molecular_function	ribosomal large subunit binding
6	0045202	cellular_component	synapse
6	0045652	biological_process	regulation of megakaryocyte differentiation
6	0045727	biological_process	positive regulation of translation
6	0070062	cellular_component	extracellular exosome
6	1902626	biological_process	assembly of large subunit precursor of preribosome
6	2000377	biological_process	regulation of reactive oxygen species metabolic process
7	0003735	molecular_function	structural constituent of ribosome
7	0005515	molecular_function	protein binding
7	0005634	cellular_component	nucleus
7	0005654	cellular_component	nucleoplasm
7	0005730	cellular_component	nucleolus
7	0005840	cellular_component	ribosome
7	0006412	biological_process	translation
7	0042254	biological_process	ribosome biogenesis
7	0042273	biological_process	ribosomal large subunit biogenesis
9	0003676	molecular_function	nucleic acid binding
9	0003677	molecular_function	DNA binding
9	0005515	molecular_function	protein binding
9	0005634	cellular_component	nucleus
9	0005654	cellular_component	nucleoplasm
9	0005730	cellular_component	nucleolus
9	0005737	cellular_component	cytoplasm
9	0008270	molecular_function	zinc ion binding
9	0042254	biological_process	ribosome biogenesis
9	0045944	biological_process	positive regulation of transcription by RNA polymerase II
9	0046872	molecular_function	metal ion binding
9	1903026	biological_process	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
9	1990275	molecular_function	preribosome binding
A	0002181	biological_process	cytoplasmic translation
A	0003723	molecular_function	RNA binding
A	0003735	molecular_function	structural constituent of ribosome
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005840	cellular_component	ribosome
A	0005925	cellular_component	focal adhesion
A	0006412	biological_process	translation
A	0014069	cellular_component	postsynaptic density
A	0015934	cellular_component	large ribosomal subunit
A	0016020	cellular_component	membrane
A	0022625	cellular_component	cytosolic large ribosomal subunit
A	0022626	cellular_component	cytosolic ribosome
A	0045471	biological_process	response to ethanol
A	0070062	cellular_component	extracellular exosome
A	1990904	cellular_component	ribonucleoprotein complex
B	0002181	biological_process	cytoplasmic translation
B	0003723	molecular_function	RNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005840	cellular_component	ribosome
B	0005925	cellular_component	focal adhesion
B	0006412	biological_process	translation
B	0022625	cellular_component	cytosolic large ribosomal subunit
B	0022626	cellular_component	cytosolic ribosome
B	0032991	cellular_component	protein-containing complex
B	0070062	cellular_component	extracellular exosome
B	0071353	biological_process	cellular response to interleukin-4
B	1990904	cellular_component	ribonucleoprotein complex
C	0002181	biological_process	cytoplasmic translation
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0007566	biological_process	embryo implantation
C	0008201	molecular_function	heparin binding
C	0016020	cellular_component	membrane
C	0022625	cellular_component	cytosolic large ribosomal subunit
C	0022626	cellular_component	cytosolic ribosome
C	0045296	molecular_function	cadherin binding
C	1990904	cellular_component	ribonucleoprotein complex
D	0002181	biological_process	cytoplasmic translation
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005730	cellular_component	nucleolus
D	0005737	cellular_component	cytoplasm
D	0005791	cellular_component	rough endoplasmic reticulum
D	0005829	cellular_component	cytosol
D	0005840	cellular_component	ribosome
D	0005925	cellular_component	focal adhesion
D	0006412	biological_process	translation
D	0016020	cellular_component	membrane
D	0022625	cellular_component	cytosolic large ribosomal subunit
D	0022626	cellular_component	cytosolic ribosome
D	0070062	cellular_component	extracellular exosome
D	1990904	cellular_component	ribonucleoprotein complex
E	0002181	biological_process	cytoplasmic translation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005840	cellular_component	ribosome
E	0005925	cellular_component	focal adhesion
E	0006412	biological_process	translation
E	0014069	cellular_component	postsynaptic density
E	0016020	cellular_component	membrane
E	0022625	cellular_component	cytosolic large ribosomal subunit
E	0022626	cellular_component	cytosolic ribosome
E	0031640	biological_process	killing of cells of another organism
E	0045202	cellular_component	synapse
E	0050829	biological_process	defense response to Gram-negative bacterium
E	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
E	0070062	cellular_component	extracellular exosome
E	1990904	cellular_component	ribonucleoprotein complex
F	0002181	biological_process	cytoplasmic translation
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005515	molecular_function	protein binding
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0005829	cellular_component	cytosol
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0022625	cellular_component	cytosolic large ribosomal subunit
F	0022626	cellular_component	cytosolic ribosome
F	0045202	cellular_component	synapse
F	0045296	molecular_function	cadherin binding
F	0070062	cellular_component	extracellular exosome
F	1990904	cellular_component	ribonucleoprotein complex
G	0000470	biological_process	maturation of LSU-rRNA
G	0002181	biological_process	cytoplasmic translation
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005730	cellular_component	nucleolus
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005840	cellular_component	ribosome
G	0005925	cellular_component	focal adhesion
G	0006412	biological_process	translation
G	0016020	cellular_component	membrane
G	0022625	cellular_component	cytosolic large ribosomal subunit
G	0022626	cellular_component	cytosolic ribosome
G	0042254	biological_process	ribosome biogenesis
G	0045202	cellular_component	synapse
G	0045296	molecular_function	cadherin binding
G	1990904	cellular_component	ribonucleoprotein complex
H	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H	0002181	biological_process	cytoplasmic translation
H	0003723	molecular_function	RNA binding
H	0003729	molecular_function	mRNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005730	cellular_component	nucleolus
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0016020	cellular_component	membrane
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	0022626	cellular_component	cytosolic ribosome
H	1990904	cellular_component	ribonucleoprotein complex
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0005925	cellular_component	focal adhesion
I	0006412	biological_process	translation
I	0016020	cellular_component	membrane
I	0019843	molecular_function	rRNA binding
I	0022625	cellular_component	cytosolic large ribosomal subunit
I	0022626	cellular_component	cytosolic ribosome
I	1990904	cellular_component	ribonucleoprotein complex
K	0002181	biological_process	cytoplasmic translation
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005730	cellular_component	nucleolus
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0016020	cellular_component	membrane
K	0022625	cellular_component	cytosolic large ribosomal subunit
K	0022626	cellular_component	cytosolic ribosome
K	0045202	cellular_component	synapse
K	1990904	cellular_component	ribonucleoprotein complex
L	0002181	biological_process	cytoplasmic translation
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005783	cellular_component	endoplasmic reticulum
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0015934	cellular_component	large ribosomal subunit
L	0016020	cellular_component	membrane
L	0022625	cellular_component	cytosolic large ribosomal subunit
L	0022626	cellular_component	cytosolic ribosome
L	1990904	cellular_component	ribonucleoprotein complex
M	0002181	biological_process	cytoplasmic translation
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0019843	molecular_function	rRNA binding
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	0022626	cellular_component	cytosolic ribosome
M	0046872	molecular_function	metal ion binding
M	0097371	molecular_function	MDM2/MDM4 family protein binding
M	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
M	1990904	cellular_component	ribonucleoprotein complex
M	1990948	molecular_function	ubiquitin ligase inhibitor activity
N	0000027	biological_process	ribosomal large subunit assembly
N	0002181	biological_process	cytoplasmic translation
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005730	cellular_component	nucleolus
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005840	cellular_component	ribosome
N	0006364	biological_process	rRNA processing
N	0006412	biological_process	translation
N	0006605	biological_process	protein targeting
N	0008097	molecular_function	5S rRNA binding
N	0010628	biological_process	positive regulation of gene expression
N	0016020	cellular_component	membrane
N	0019843	molecular_function	rRNA binding
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	0022626	cellular_component	cytosolic ribosome
N	0031625	molecular_function	ubiquitin protein ligase binding
N	0032092	biological_process	positive regulation of protein binding
N	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
N	0032991	cellular_component	protein-containing complex
N	0034504	biological_process	protein localization to nucleus
N	0042273	biological_process	ribosomal large subunit biogenesis
N	0050821	biological_process	protein stabilization
N	0070062	cellular_component	extracellular exosome
N	1901796	biological_process	regulation of signal transduction by p53 class mediator
N	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
N	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
N	1990904	cellular_component	ribonucleoprotein complex
N	1990948	molecular_function	ubiquitin ligase inhibitor activity
N	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
N	2000435	biological_process	negative regulation of protein neddylation
O	0001501	biological_process	skeletal system development
O	0001503	biological_process	ossification
O	0002181	biological_process	cytoplasmic translation
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005515	molecular_function	protein binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0005925	cellular_component	focal adhesion
O	0006412	biological_process	translation
O	0006417	biological_process	regulation of translation
O	0007605	biological_process	sensory perception of sound
O	0014069	cellular_component	postsynaptic density
O	0022618	biological_process	protein-RNA complex assembly
O	0022625	cellular_component	cytosolic large ribosomal subunit
O	0022626	cellular_component	cytosolic ribosome
O	0033291	cellular_component	eukaryotic 80S initiation complex
O	0034463	biological_process	90S preribosome assembly
O	0042474	biological_process	middle ear morphogenesis
O	0045202	cellular_component	synapse
O	0048318	biological_process	axial mesoderm development
O	1990904	cellular_component	ribonucleoprotein complex
P	0002181	biological_process	cytoplasmic translation
P	0002227	biological_process	innate immune response in mucosa
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005615	cellular_component	extracellular space
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0019731	biological_process	antibacterial humoral response
P	0022625	cellular_component	cytosolic large ribosomal subunit
P	0022626	cellular_component	cytosolic ribosome
P	0050830	biological_process	defense response to Gram-positive bacterium
P	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
P	1990904	cellular_component	ribonucleoprotein complex
Q	0001824	biological_process	blastocyst development
Q	0002181	biological_process	cytoplasmic translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005730	cellular_component	nucleolus
Q	0005737	cellular_component	cytoplasm
Q	0005783	cellular_component	endoplasmic reticulum
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0016020	cellular_component	membrane
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	0022626	cellular_component	cytosolic ribosome
Q	0045202	cellular_component	synapse
Q	0060348	biological_process	bone development
Q	1990904	cellular_component	ribonucleoprotein complex
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005730	cellular_component	nucleolus
R	0042254	biological_process	ribosome biogenesis
R	0042273	biological_process	ribosomal large subunit biogenesis
R	1990275	molecular_function	preribosome binding
S	0002181	biological_process	cytoplasmic translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006364	biological_process	rRNA processing
S	0006412	biological_process	translation
S	0014069	cellular_component	postsynaptic density
S	0016020	cellular_component	membrane
S	0022625	cellular_component	cytosolic large ribosomal subunit
S	0022626	cellular_component	cytosolic ribosome
S	0042273	biological_process	ribosomal large subunit biogenesis
S	0045202	cellular_component	synapse
S	0045296	molecular_function	cadherin binding
S	0070062	cellular_component	extracellular exosome
S	1990904	cellular_component	ribonucleoprotein complex
U	0002181	biological_process	cytoplasmic translation
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0022625	cellular_component	cytosolic large ribosomal subunit
U	0022626	cellular_component	cytosolic ribosome
U	0031672	cellular_component	A band
U	0045202	cellular_component	synapse
U	0045296	molecular_function	cadherin binding
U	0045471	biological_process	response to ethanol
U	1990904	cellular_component	ribonucleoprotein complex
V	0002181	biological_process	cytoplasmic translation
V	0003723	molecular_function	RNA binding
V	0003729	molecular_function	mRNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005634	cellular_component	nucleus
V	0005730	cellular_component	nucleolus
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0005925	cellular_component	focal adhesion
V	0006412	biological_process	translation
V	0006417	biological_process	regulation of translation
V	0015934	cellular_component	large ribosomal subunit
V	0016020	cellular_component	membrane
V	0017148	biological_process	negative regulation of translation
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	0022626	cellular_component	cytosolic ribosome
V	0032496	biological_process	response to lipopolysaccharide
V	0042592	biological_process	homeostatic process
V	0045202	cellular_component	synapse
V	0048246	biological_process	macrophage chemotaxis
V	0060425	biological_process	lung morphogenesis
V	0071346	biological_process	cellular response to type II interferon
V	0097452	cellular_component	GAIT complex
V	1901194	biological_process	negative regulation of formation of translation preinitiation complex
V	1990904	cellular_component	ribonucleoprotein complex
W	0002181	biological_process	cytoplasmic translation
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0005515	molecular_function	protein binding
W	0005737	cellular_component	cytoplasm
W	0005783	cellular_component	endoplasmic reticulum
W	0005829	cellular_component	cytosol
W	0005840	cellular_component	ribosome
W	0005886	cellular_component	plasma membrane
W	0006412	biological_process	translation
W	0022625	cellular_component	cytosolic large ribosomal subunit
W	0022626	cellular_component	cytosolic ribosome
W	1990904	cellular_component	ribonucleoprotein complex
X	0002181	biological_process	cytoplasmic translation
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0005925	cellular_component	focal adhesion
X	0006412	biological_process	translation
X	0022625	cellular_component	cytosolic large ribosomal subunit
X	0022626	cellular_component	cytosolic ribosome
X	0046872	molecular_function	metal ion binding
X	0070062	cellular_component	extracellular exosome
X	1990904	cellular_component	ribonucleoprotein complex
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0015934	cellular_component	large ribosomal subunit
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	0022626	cellular_component	cytosolic ribosome
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0002181	biological_process	cytoplasmic translation
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005730	cellular_component	nucleolus
Z	0005737	cellular_component	cytoplasm
Z	0005783	cellular_component	endoplasmic reticulum
Z	0005791	cellular_component	rough endoplasmic reticulum
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0005925	cellular_component	focal adhesion
Z	0006412	biological_process	translation
Z	0016020	cellular_component	membrane
Z	0022625	cellular_component	cytosolic large ribosomal subunit
Z	0022626	cellular_component	cytosolic ribosome
Z	0043232	cellular_component	intracellular non-membrane-bounded organelle
Z	1990904	cellular_component	ribonucleoprotein complex
a	0002181	biological_process	cytoplasmic translation
a	0003723	molecular_function	RNA binding
a	0003735	molecular_function	structural constituent of ribosome
a	0005515	molecular_function	protein binding
a	0005730	cellular_component	nucleolus
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0005840	cellular_component	ribosome
a	0005925	cellular_component	focal adhesion
a	0006412	biological_process	translation
a	0016020	cellular_component	membrane
a	0022625	cellular_component	cytosolic large ribosomal subunit
a	0022626	cellular_component	cytosolic ribosome
a	0045202	cellular_component	synapse
a	1990904	cellular_component	ribonucleoprotein complex
b	0002181	biological_process	cytoplasmic translation
b	0003723	molecular_function	RNA binding
b	0003735	molecular_function	structural constituent of ribosome
b	0005515	molecular_function	protein binding
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0016020	cellular_component	membrane
b	0022625	cellular_component	cytosolic large ribosomal subunit
b	0022626	cellular_component	cytosolic ribosome
b	1990904	cellular_component	ribonucleoprotein complex
c	0002181	biological_process	cytoplasmic translation
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0005515	molecular_function	protein binding
c	0005737	cellular_component	cytoplasm
c	0005783	cellular_component	endoplasmic reticulum
c	0005829	cellular_component	cytosol
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0016020	cellular_component	membrane
c	0022625	cellular_component	cytosolic large ribosomal subunit
c	0022626	cellular_component	cytosolic ribosome
c	0045202	cellular_component	synapse
c	1990904	cellular_component	ribonucleoprotein complex
d	0002181	biological_process	cytoplasmic translation
d	0003723	molecular_function	RNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0005925	cellular_component	focal adhesion
d	0006412	biological_process	translation
d	0008201	molecular_function	heparin binding
d	0022625	cellular_component	cytosolic large ribosomal subunit
d	0022626	cellular_component	cytosolic ribosome
d	0042802	molecular_function	identical protein binding
d	0045202	cellular_component	synapse
d	0046632	biological_process	alpha-beta T cell differentiation
d	0070062	cellular_component	extracellular exosome
d	0098793	cellular_component	presynapse
d	0098978	cellular_component	glutamatergic synapse
d	0140236	biological_process	translation at presynapse
d	1990904	cellular_component	ribonucleoprotein complex
e	0000122	biological_process	negative regulation of transcription by RNA polymerase II
e	0001223	molecular_function	transcription coactivator binding
e	0002181	biological_process	cytoplasmic translation
e	0003723	molecular_function	RNA binding
e	0003735	molecular_function	structural constituent of ribosome
e	0005515	molecular_function	protein binding
e	0005654	cellular_component	nucleoplasm
e	0005730	cellular_component	nucleolus
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0005840	cellular_component	ribosome
e	0005925	cellular_component	focal adhesion
e	0006412	biological_process	translation
e	0006610	biological_process	ribosomal protein import into nucleus
e	0008284	biological_process	positive regulation of cell population proliferation
e	0010628	biological_process	positive regulation of gene expression
e	0016020	cellular_component	membrane
e	0022625	cellular_component	cytosolic large ribosomal subunit
e	0022626	cellular_component	cytosolic ribosome
e	0031625	molecular_function	ubiquitin protein ligase binding
e	0032986	biological_process	protein-DNA complex disassembly
e	0032991	cellular_component	protein-containing complex
e	0045202	cellular_component	synapse
e	0050821	biological_process	protein stabilization
e	0070062	cellular_component	extracellular exosome
e	0070180	molecular_function	large ribosomal subunit rRNA binding
e	0070314	biological_process	G1 to G0 transition
e	0072717	biological_process	cellular response to actinomycin D
e	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
e	1903450	biological_process	regulation of G1 to G0 transition
e	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
e	1990904	cellular_component	ribonucleoprotein complex
e	1990948	molecular_function	ubiquitin ligase inhibitor activity
e	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
g	0002181	biological_process	cytoplasmic translation
g	0003723	molecular_function	RNA binding
g	0003735	molecular_function	structural constituent of ribosome
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005730	cellular_component	nucleolus
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0019843	molecular_function	rRNA binding
g	0022625	cellular_component	cytosolic large ribosomal subunit
g	0022626	cellular_component	cytosolic ribosome
g	0045296	molecular_function	cadherin binding
g	0070062	cellular_component	extracellular exosome
g	1904841	molecular_function	TORC2 complex binding
g	1990904	cellular_component	ribonucleoprotein complex
h	0002181	biological_process	cytoplasmic translation
h	0003723	molecular_function	RNA binding
h	0003735	molecular_function	structural constituent of ribosome
h	0005515	molecular_function	protein binding
h	0005654	cellular_component	nucleoplasm
h	0005730	cellular_component	nucleolus
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0005840	cellular_component	ribosome
h	0006364	biological_process	rRNA processing
h	0006412	biological_process	translation
h	0006977	biological_process	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
h	0015934	cellular_component	large ribosomal subunit
h	0016020	cellular_component	membrane
h	0022625	cellular_component	cytosolic large ribosomal subunit
h	0022626	cellular_component	cytosolic ribosome
h	0034644	biological_process	cellular response to UV
h	0042273	biological_process	ribosomal large subunit biogenesis
h	0045202	cellular_component	synapse
h	0045727	biological_process	positive regulation of translation
h	0048027	molecular_function	mRNA 5'-UTR binding
h	0070062	cellular_component	extracellular exosome
h	0071479	biological_process	cellular response to ionizing radiation
h	0071480	biological_process	cellular response to gamma radiation
h	1902164	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
h	1902167	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
h	1904803	biological_process	regulation of translation involved in cellular response to UV
h	1990904	cellular_component	ribonucleoprotein complex
i	0002181	biological_process	cytoplasmic translation
i	0003723	molecular_function	RNA binding
i	0003735	molecular_function	structural constituent of ribosome
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005730	cellular_component	nucleolus
i	0005737	cellular_component	cytoplasm
i	0005783	cellular_component	endoplasmic reticulum
i	0005791	cellular_component	rough endoplasmic reticulum
i	0005829	cellular_component	cytosol
i	0005840	cellular_component	ribosome
i	0005925	cellular_component	focal adhesion
i	0006364	biological_process	rRNA processing
i	0006412	biological_process	translation
i	0016020	cellular_component	membrane
i	0022625	cellular_component	cytosolic large ribosomal subunit
i	0022626	cellular_component	cytosolic ribosome
i	0045202	cellular_component	synapse
i	0070062	cellular_component	extracellular exosome
i	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
i	1904044	biological_process	response to aldosterone
i	1990904	cellular_component	ribonucleoprotein complex
j	0002181	biological_process	cytoplasmic translation
j	0003723	molecular_function	RNA binding
j	0003735	molecular_function	structural constituent of ribosome
j	0005515	molecular_function	protein binding
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005840	cellular_component	ribosome
j	0005925	cellular_component	focal adhesion
j	0006412	biological_process	translation
j	0016020	cellular_component	membrane
j	0022625	cellular_component	cytosolic large ribosomal subunit
j	0022626	cellular_component	cytosolic ribosome
j	0070062	cellular_component	extracellular exosome
j	1990904	cellular_component	ribonucleoprotein complex
k	0002181	biological_process	cytoplasmic translation
k	0003723	molecular_function	RNA binding
k	0003735	molecular_function	structural constituent of ribosome
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0016020	cellular_component	membrane
k	0022625	cellular_component	cytosolic large ribosomal subunit
k	0022626	cellular_component	cytosolic ribosome
k	1990904	cellular_component	ribonucleoprotein complex
l	0002181	biological_process	cytoplasmic translation
l	0003723	molecular_function	RNA binding
l	0003735	molecular_function	structural constituent of ribosome
l	0005515	molecular_function	protein binding
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0005840	cellular_component	ribosome
l	0006412	biological_process	translation
l	0016020	cellular_component	membrane
l	0022625	cellular_component	cytosolic large ribosomal subunit
l	0022626	cellular_component	cytosolic ribosome
l	0030425	cellular_component	dendrite
l	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
l	0044297	cellular_component	cell body
l	0045202	cellular_component	synapse
l	0070062	cellular_component	extracellular exosome
l	1990904	cellular_component	ribonucleoprotein complex
m	0002181	biological_process	cytoplasmic translation
m	0003723	molecular_function	RNA binding
m	0003735	molecular_function	structural constituent of ribosome
m	0005515	molecular_function	protein binding
m	0005654	cellular_component	nucleoplasm
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0005840	cellular_component	ribosome
m	0005925	cellular_component	focal adhesion
m	0006412	biological_process	translation
m	0014069	cellular_component	postsynaptic density
m	0015934	cellular_component	large ribosomal subunit
m	0016020	cellular_component	membrane
m	0019843	molecular_function	rRNA binding
m	0022625	cellular_component	cytosolic large ribosomal subunit
m	0022626	cellular_component	cytosolic ribosome
m	0045202	cellular_component	synapse
m	0098794	cellular_component	postsynapse
m	1990904	cellular_component	ribonucleoprotein complex
n	0000049	molecular_function	tRNA binding
n	0002181	biological_process	cytoplasmic translation
n	0003723	molecular_function	RNA binding
n	0003735	molecular_function	structural constituent of ribosome
n	0005515	molecular_function	protein binding
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0005840	cellular_component	ribosome
n	0006364	biological_process	rRNA processing
n	0006412	biological_process	translation
n	0016020	cellular_component	membrane
n	0022625	cellular_component	cytosolic large ribosomal subunit
n	0022626	cellular_component	cytosolic ribosome
n	0042273	biological_process	ribosomal large subunit biogenesis
n	0070062	cellular_component	extracellular exosome
n	1990904	cellular_component	ribonucleoprotein complex
o	0002181	biological_process	cytoplasmic translation
o	0003677	molecular_function	DNA binding
o	0003723	molecular_function	RNA binding
o	0003735	molecular_function	structural constituent of ribosome
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0005737	cellular_component	cytoplasm
o	0005783	cellular_component	endoplasmic reticulum
o	0005791	cellular_component	rough endoplasmic reticulum
o	0005829	cellular_component	cytosol
o	0005840	cellular_component	ribosome
o	0005925	cellular_component	focal adhesion
o	0006355	biological_process	regulation of DNA-templated transcription
o	0006412	biological_process	translation
o	0014069	cellular_component	postsynaptic density
o	0016020	cellular_component	membrane
o	0022625	cellular_component	cytosolic large ribosomal subunit
o	0022626	cellular_component	cytosolic ribosome
o	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
o	0045202	cellular_component	synapse
o	0045296	molecular_function	cadherin binding
o	1990904	cellular_component	ribonucleoprotein complex
p	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
p	0002181	biological_process	cytoplasmic translation
p	0003677	molecular_function	DNA binding
p	0003723	molecular_function	RNA binding
p	0003729	molecular_function	mRNA binding
p	0003735	molecular_function	structural constituent of ribosome
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005730	cellular_component	nucleolus
p	0005737	cellular_component	cytoplasm
p	0005829	cellular_component	cytosol
p	0005840	cellular_component	ribosome
p	0005925	cellular_component	focal adhesion
p	0006364	biological_process	rRNA processing
p	0006412	biological_process	translation
p	0014069	cellular_component	postsynaptic density
p	0016020	cellular_component	membrane
p	0022625	cellular_component	cytosolic large ribosomal subunit
p	0022626	cellular_component	cytosolic ribosome
p	0042273	biological_process	ribosomal large subunit biogenesis
p	0042802	molecular_function	identical protein binding
p	1990904	cellular_component	ribonucleoprotein complex
r	0000027	biological_process	ribosomal large subunit assembly
r	0002181	biological_process	cytoplasmic translation
r	0003723	molecular_function	RNA binding
r	0003730	molecular_function	mRNA 3'-UTR binding
r	0003735	molecular_function	structural constituent of ribosome
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0005730	cellular_component	nucleolus
r	0005737	cellular_component	cytoplasm
r	0005783	cellular_component	endoplasmic reticulum
r	0005829	cellular_component	cytosol
r	0005840	cellular_component	ribosome
r	0005925	cellular_component	focal adhesion
r	0006364	biological_process	rRNA processing
r	0006412	biological_process	translation
r	0008097	molecular_function	5S rRNA binding
r	0010628	biological_process	positive regulation of gene expression
r	0016020	cellular_component	membrane
r	0019843	molecular_function	rRNA binding
r	0022625	cellular_component	cytosolic large ribosomal subunit
r	0022626	cellular_component	cytosolic ribosome
r	0031625	molecular_function	ubiquitin protein ligase binding
r	0032991	cellular_component	protein-containing complex
r	0042273	biological_process	ribosomal large subunit biogenesis
r	0045727	biological_process	positive regulation of translation
r	0048027	molecular_function	mRNA 5'-UTR binding
r	0050821	biological_process	protein stabilization
r	0070062	cellular_component	extracellular exosome
r	1901796	biological_process	regulation of signal transduction by p53 class mediator
r	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
r	1990904	cellular_component	ribonucleoprotein complex
r	1990948	molecular_function	ubiquitin ligase inhibitor activity
r	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
r	2000435	biological_process	negative regulation of protein neddylation
z	0001099	molecular_function	basal RNA polymerase II transcription machinery binding
z	0003723	molecular_function	RNA binding
z	0005515	molecular_function	protein binding
z	0005634	cellular_component	nucleus
z	0005694	cellular_component	chromosome
z	0005730	cellular_component	nucleolus
z	0060999	biological_process	positive regulation of dendritic spine development
z	0097484	biological_process	dendrite extension

Functional Information from PROSITE/UniProt

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqtLKmiRqGkaKlVIL

Chain	Residue	Details
E	SER24-LEU48

---

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLaIiDpG

Chain	Residue	Details
E	GLU80-GLY100

---

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TaSnKtrlsRTPGN

Chain	Residue	Details
F	THR15-ASN28

---

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG

Chain	Residue	Details
U	ASP46-GLY69

---

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM

Chain	Residue	Details
Z	LYS49-MET66

---

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP

Chain	Residue	Details
a	GLN7-PRO26

---

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG

Chain	Residue	Details
V	VAL84-GLY107

---

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK

Chain	Residue	Details
K	PRO52-LYS62

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL

Chain	Residue	Details
Y	ARG126-LEU150

---

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG

Chain	Residue	Details
j	VAL62-GLY76

---

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIksvG

Chain	Residue	Details
L	LYS110-GLY141

---

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI

Chain	Residue	Details
e	ALA79-ILE105

---

site_id	PS01108
Number of Residues	19
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV

Chain	Residue	Details
h	ASP52-VAL70

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR

Chain	Residue	Details
B	PHE211-ARG234

---

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FcSgpIyPGhGmmFvRnD

Chain	Residue	Details
7	PHE8-ASP25

---

site_id	PS01199
Number of Residues	20
Details	RIBOSOMAL_L1 Ribosomal protein L1 signature. IkqIpriLGpgLNKAGkFPS

Chain	Residue	Details
A	ILE117-SER136

---

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK

Chain	Residue	Details
I	GLN163-LYS184

---

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE

Chain	Residue	Details
m	PRO197-GLU208

---

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP

Chain	Residue	Details
n	GLY72-PRO93

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciIkGKarLG

Chain	Residue	Details
G	CYS174-GLY191

---

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K

Chain	Residue	Details
o	ASN182-LYS200

---

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR

Chain	Residue	Details
P	LYS30-ARG46

---

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG

Chain	Residue	Details
M	GLY4-GLY23

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV

Chain	Residue	Details
H	LYS43-VAL57

---

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG

Chain	Residue	Details
k	PHE20-GLY40

---

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cla..CaryFidstnlktHfrskdH

Chain	Residue	Details
9	CYS63-HIS85

---

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLRleC

Chain	Residue	Details
W	LYS61-CYS72

---

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV

Chain	Residue	Details
g	LYS134-VAL149

---

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLrQifNgTfvklnkasinMLriVepYI

Chain	Residue	Details
p	VAL108-ILE140

---

site_id	PS01107
Number of Residues	12
Details	RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF

Chain	Residue	Details
i	GLY125-PHE136

---

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG

Chain	Residue	Details
Q	ARG71-GLY85

---

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT

Chain	Residue	Details
N	LEU40-THR56

---

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV

Chain	Residue	Details
D	GLY15-VAL22

---

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH

Chain	Residue	Details
D	ASN116-HIS142

---

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG

Chain	Residue	Details
c	GLY37-GLY62

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733

Chain	Residue	Details
o	LYS207
z	LYS67
a	ARG38

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:28112733

Chain	Residue	Details
r	LYS5
z	LYS74
m	LYS149
m	LYS234
m	LYS250

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
G	LYS245
r	SER185
j	LYS70
l	LYS65
G	LYS21
G	LYS48
G	LYS125

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P47962

Chain	Residue	Details
r	LYS220
O	LYS9

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
r	THR232
B	LYS366

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
b	LYS170
r	SER272
b	LYS128

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25114211

Chain	Residue	Details
B	LYS386
B	LYS393
Q	LYS177
r	LYS220
Q	LYS174

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Citrulline => ECO:0000250|UniProtKB:Q9D8E6

Chain	Residue	Details
D	ARG300
B	LYS399

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:Q9D8E6

Chain	Residue	Details
D	LYS364
B	LYS366

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:20068231

Chain	Residue	Details
4	LYS332
4	LYS534
D	SER365

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
D	LYS239
D	LYS327

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate => ECO:0007744|PubMed:25114211

Chain	Residue	Details
D	LYS364

---